Source: INFERRED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923 341
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846 327
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923 286
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808 221
SUFU Q9UMX1 SUFU negative regulator of hedgehog signaling 1.00 0.493 0.769 209
BAZ1B Q9UIG0 bromodomain adjacent to zinc finger domain 1B 1.00 0.530 0.731 202
TTN Q8WZ42 titin Kinase 2.6E-96 0.470 0.885 192
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923 190
SKI P12755 SKI proto-oncogene 1.00 0.503 0.808 171
TCF4 P15884 transcription factor 4 Transcription factor 1.00 0.464 0.846 165
SETBP1 Q9Y6X0 SET binding protein 1 1.00 0.503 0.808 160
WT1 P19544 WT1 transcription factor Nucleic acid binding 1.00 0.422 0.808 151
RERE Q9P2R6 arginine-glutamic acid dipeptide repeats 1.00 0.526 0.846 148
CEP120 Q8N960 centrosomal protein 120 4.1E-15 0.564 0.731 142
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923 140
ARVCF O00192 ARVCF delta catenin family member Cellular structure 5.0E-11 0.540 0.769 139
SH2B3 Q9UQQ2 SH2B adaptor protein 3 1.0E-04 0.527 0.692 135
PLEC Q15149 plectin Cellular structure 8.3E-12 0.523 0.808 133
PRDM16 Q9HAZ2 PR/SET domain 16 1.00 0.522 0.808 132
KCNQ1 P51787 potassium voltage-gated channel subfamily Q member 1 Ion channel 4.5E-08 0.485 0.769 131
GATA4 P43694 GATA binding protein 4 0.49 0.458 0.846 130
INSR P06213 insulin receptor Kinase 3.6E-05 0.432 0.846 128
RTEL1 Q9NZ71 regulator of telomere elongation helicase 1 Enzyme 8.9E-10 0.459 0.808 124
ASXL3 Q9C0F0 ASXL transcriptional regulator 3 1.00 0.590 0.577 118