Source: ALL

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962 2494 527
IL6 P05231 interleukin 6 0.32 0.248 0.962 2367 22
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923 1679 21
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885 1456 27
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962 1250 33
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923 1193 57
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923 821 17
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923 666 9
MIR155 microRNA 155 0.384 0.885 584 1
NFKB1 P19838 nuclear factor kappa B subunit 1 Transcription factor 1.00 0.396 0.923 551 52
CD40 P25942 CD40 molecule 0.85 0.396 0.846 528 21
MYD88 Q99836 MYD88 innate immune signal transduction adaptor Enzyme modulator 0.12 0.414 0.923 480 9
ABCB6 Q9NP58 ATP binding cassette subfamily B member 6 (Langereis blood group) Transporter 8.6E-19 0.431 0.885 400 19
GBA P04062 glucosylceramidase beta 1.4E-06 0.500 0.808 319 157
FOXP1 Q9H334 forkhead box P1 1.00 0.460 0.808 317 64
BCL6 P41182 BCL6 transcription repressor 0.96 0.444 0.808 309 3
BTK Q06187 Bruton tyrosine kinase Kinase 1.00 0.464 0.808 290 85
DDIT3 P35638 DNA damage inducible transcript 3 0.59 0.467 0.846 264 1
FBXW7 Q969H0 F-box and WD repeat domain containing 7 Enzyme modulator 1.00 0.465 0.808 257 16
HDAC4 P56524 histone deacetylase 4 Epigenetic regulator 1.00 0.484 0.885 256 9
JAK1 P23458 Janus kinase 1 Kinase 1.00 0.474 0.769 239 41
NFKBIA P25963 NFKB inhibitor alpha 0.99 0.487 0.885 226 19
GLS O94925 glutaminase Enzyme 0.96 0.489 0.808 217 4
ARHGEF7 Q14155 Rho guanine nucleotide exchange factor 7 1.00 0.486 0.846 215 14