Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
GCKR Q14397 glucokinase regulator 8.5E-19 0.604 0.615 79 13
CDKN2B-AS1 CDKN2B antisense RNA 1 0.491 0.769 69 53
ALDH1A2 O94788 aldehyde dehydrogenase 1 family member A2 Enzyme 0.36 0.578 0.692 45 46
TMEM258 P61165 transmembrane protein 258 1.9E-03 0.644 0.654 40 13
ZPR1 O75312 ZPR1 zinc finger 8.9E-09 0.674 0.462 36 16
COL4A2 P08572 collagen type IV alpha 2 chain 3.6E-15 0.563 0.654 23 22
LRP1B Q9NZR2 LDL receptor related protein 1B 2.5E-06 0.626 0.615 21 26
FRY Q5TBA9 FRY microtubule binding protein 1.00 0.666 0.500 21 6
SPC25 Q9HBM1 SPC25 component of NDC80 kinetochore complex 2.6E-02 0.729 0.346 20 16
SERPINA1 P01009 serpin family A member 1 Enzyme modulator 6.8E-08 0.410 0.923 20 4
ABCA1 O95477 ATP binding cassette subfamily A member 1 Transporter 1.5E-13 0.467 0.846 19 29
PTPRN2 Q92932 protein tyrosine phosphatase receptor type N2 5.4E-07 0.678 0.577 18 14
PHACTR1 Q9C0D0 phosphatase and actin regulator 1 Enzyme modulator 0.64 0.663 0.423 16 21
APOB P04114 apolipoprotein B 1.9E-16 0.453 0.808 16 16
ATXN1 P54253 ataxin 1 0.97 0.534 0.769 15 15
TXNL4B Q9NX01 thioredoxin like 4B 4.4E-03 0.931 0.077 15 9
GALNT2 Q10471 polypeptide N-acetylgalactosaminyltransferase 2 Enzyme 8.4E-03 0.678 0.538 14 41
DOCK7 Q96N67 dedicator of cytokinesis 7 Enzyme modulator 6.4E-06 0.682 0.423 11 30
LINC02245 long intergenic non-protein coding RNA 2245 0.821 0.231 11 14
GRK6 P43250 G protein-coupled receptor kinase 6 Kinase 4.9E-04 0.670 0.654 11 11
G6PC2 Q9NQR9 glucose-6-phosphatase catalytic subunit 2 3.0E-16 0.751 0.231 9 4
KLKB1 P03952 kallikrein B1 Enzyme 6.3E-13 0.604 0.692 8 21
MAGI2 Q86UL8 membrane associated guanylate kinase, WW and PDZ domain containing 2 1.00 0.579 0.654 8 10
LDLR P01130 low density lipoprotein receptor 9.8E-24 0.449 0.885 7 12