Source: ALL

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
RYR1 P21817 ryanodine receptor 1 Ion channel 1.6E-29 0.489 0.808 320 248
KCNQ1 P51787 potassium voltage-gated channel subfamily Q member 1 Ion channel 4.5E-08 0.485 0.769 281 380
CALM1 P0DP23 P0DP24 P0DP25 calmodulin 1 Calcium-binding protein 0.94 0.472 0.808 253 10
CALM2 P0DP23 P0DP24 P0DP25 calmodulin 2 Calcium-binding protein 0.92 0.472 0.808 252 12
FXN Q16595 frataxin Enzyme 0.34 0.510 0.654 220 21
SCN5A Q14524 sodium voltage-gated channel alpha subunit 5 Ion channel 0.91 0.513 0.654 216 504
AIP O00170 aryl hydrocarbon receptor interacting protein Chaperone 0.36 0.517 0.769 216 24
CALM3 P0DP23 P0DP24 P0DP25 calmodulin 3 Calcium-binding protein 0.93 0.485 0.846 215 3
KRIT1 O00522 KRIT1 ankyrin repeat containing 6.9E-04 0.500 0.808 201 43
KCNH2 Q12809 potassium voltage-gated channel subfamily H member 2 Ion channel 1.00 0.522 0.731 189 386
CAMKMT Q7Z624 calmodulin-lysine N-methyltransferase 1.4E-15 0.510 0.808 185 6
RYR2 Q92736 ryanodine receptor 2 Ion channel 1.00 0.539 0.615 160 116
CAVIN1 Q6NZI2 caveolae associated protein 1 Transcription factor 5.0E-03 0.559 0.654 151 14
SCN10A Q9Y5Y9 sodium voltage-gated channel alpha subunit 10 Ion channel 9.9E-38 0.566 0.692 147 34
CACNA1S Q13698 calcium voltage-gated channel subunit alpha1 S Ion channel 6.3E-12 0.595 0.692 118 22
KCNJ2 P63252 potassium inwardly rectifying channel subfamily J member 2 Ion channel 0.31 0.572 0.731 117 33
KCNE1 P15382 potassium voltage-gated channel subfamily E regulatory subunit 1 Ion channel 3.4E-03 0.588 0.615 95 50
PICALM Q13492 phosphatidylinositol binding clathrin assembly protein Transporter 1.00 0.592 0.538 79 22
CNTN3 Q9P232 contactin 3 2.0E-05 0.612 0.654 77 2
CTRL P40313 chymotrypsin like Enzyme 1.1E-09 0.599 0.846 76 0
ANK2 Q01484 ankyrin 2 1.00 0.626 0.538 71 37
ASPH Q12797 aspartate beta-hydroxylase 6.6E-15 0.610 0.615 69 6
KCNE2 Q9Y6J6 potassium voltage-gated channel subfamily E regulatory subunit 2 Ion channel 1.0E-04 0.628 0.423 66 14
SNAP91 O60641 synaptosome associated protein 91 Transporter 1.00 0.638 0.538 53 9