Source: ALL

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962 2724 31
IL6 P05231 interleukin 6 0.32 0.248 0.962 2367 22
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923 1899 59
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 1801 22
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923 1679 21
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962 1558 50
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923 1337 31
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962 1254 10
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962 1174 54
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962 1157 8
IL17A Q16552 interleukin 17A 4.3E-02 0.324 0.923 1074 19
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923 1044 15
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923 1021 43
IL1A P01583 interleukin 1 alpha 1.6E-04 0.333 0.962 1002 19
IL4 P05112 interleukin 4 4.7E-03 0.332 0.962 996 23
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885 824 13
TLR2 O60603 toll like receptor 2 1.0E-06 0.361 0.923 749 15
FN1 P02751 fibronectin 1 Signaling 1.4E-03 0.365 0.962 724 33
CD44 P16070 CD44 molecule (Indian blood group) 2.4E-07 0.363 0.962 711 47
TERT O14746 telomerase reverse transcriptase Enzyme 0.99 0.374 0.846 703 97
IL1RN P18510 interleukin 1 receptor antagonist 3.1E-02 0.373 0.923 701 52
MPO P05164 myeloperoxidase Enzyme 7.1E-15 0.377 0.923 653 25
FGF2 P09038 fibroblast growth factor 2 Signaling 1.8E-02 0.383 0.923 635 7
IL22 Q9GZX6 interleukin 22 1.9E-04 0.393 0.885 551 9