| Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI g | DPI g | Num. diseases |
|---|---|---|---|---|---|---|---|
| VHL | P40337 | von Hippel-Lindau tumor suppressor | Enzyme | 8.0E-02 | 0.443 | 0.846 | 22 |
| ACVRL1 | P37023 | activin A receptor like type 1 | Kinase | 9.7E-04 | 0.493 | 0.769 | 14 |
| SMAD4 | Q13485 | SMAD family member 4 | Transcription factor | 1.00 | 0.401 | 0.808 | 13 |
| BMPR2 | Q13873 | bone morphogenetic protein receptor type 2 | Kinase | 1.00 | 0.538 | 0.654 | 9 |
| EIF2AK4 | Q9P2K8 | eukaryotic translation initiation factor 2 alpha kinase 4 | 1.2E-15 | 0.603 | 0.577 | 8 | |
| SMAD9 | O15198 | SMAD family member 9 | Transcription factor | 6.4E-05 | 0.666 | 0.308 | 8 |
| TBX4 | P57082 | T-box transcription factor 4 | Transcription factor | 0.50 | 0.576 | 0.731 | 8 |
| CAV1 | Q03135 | caveolin 1 | Enzyme modulator | 8.3E-03 | 0.388 | 0.885 | 7 |
| KCNK3 | O14649 | potassium two pore domain channel subfamily K member 3 | Ion channel | 0.90 | 0.584 | 0.654 | 6 |
| EPAS1 | Q99814 | endothelial PAS domain protein 1 | Transcription factor | 0.60 | 0.454 | 0.731 | 4 |