Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
WT1 P19544 WT1 transcription factor Nucleic acid binding 1.00 0.422 0.808 446 61
ABO P16442 ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase Enzyme 0.427 0.885 443 160
CHRM3 P20309 cholinergic receptor muscarinic 3 G-protein coupled receptor 0.99 0.464 0.885 284 17
IL6R P08887 interleukin 6 receptor Signaling 3.2E-05 0.471 0.846 261 36
ITPR1 Q14643 inositol 1,4,5-trisphosphate receptor type 1 Ion channel 1.00 0.534 0.846 185 34
SERPINE2 P07093 serpin family E member 2 Enzyme modulator 0.73 0.592 0.692 87 12
ICA1 Q05084 islet cell autoantigen 1 9.9E-04 0.686 0.500 34 3
VPS13D Q5THJ4 vacuolar protein sorting 13 homolog D 1.1E-06 0.769 0.346 33 14
PLCL2 Q9UPR0 phospholipase C like 2 Enzyme 1.00 0.743 0.308 30 30
KSR2 Q6VAB6 kinase suppressor of ras 2 Kinase 1.00 0.743 0.231 27 13
SORBS2 O94875 sorbin and SH3 domain containing 2 3.6E-02 0.736 0.423 25 10
MDGA2 Q7Z553 MAM domain containing glycosylphosphatidylinositol anchor 2 0.66 0.760 0.308 24 13
TC2N Q8N9U0 tandem C2 domains, nuclear 1.2E-09 0.805 0.154 17 17
MIR99AHG mir-99a-let-7c cluster host gene 0.780 0.192 17 11
EFCAB13 Q8IY85 EF-hand calcium binding domain 13 6.5E-32 0.890 0.115 11 5
RNF220 Q5VTB9 ring finger protein 220 1.00 1.000 0.038 4 3
SH2D7 A6NKC9 SH2 domain containing 7 2.4E-08 1 1