Source: INFERRED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923 341
TP63 Q9H3D4 tumor protein p63 Transcription factor 1.00 0.362 0.769 266
ELN P15502 elastin 2.1E-14 0.415 0.885 257
GNAS O95467 P63092 P84996 Q5JWF2 GNAS complex locus Enzyme modulator 0.68 0.420 0.885 232
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885 229
OFD1 O75665 OFD1 centriole and centriolar satellite protein 0.96 0.510 0.808 225
GJA1 P17302 gap junction protein alpha 1 Cell-cell junction 0.16 0.393 0.885 224
PEX6 Q13608 peroxisomal biogenesis factor 6 6.3E-06 0.547 0.731 212
PEX1 O43933 peroxisomal biogenesis factor 1 1.1E-14 0.538 0.769 209
TBX1 O43435 T-box transcription factor 1 Transcription factor 0.84 0.433 0.808 207
BAZ1B Q9UIG0 bromodomain adjacent to zinc finger domain 1B 1.00 0.530 0.731 202
DHCR7 Q9UBM7 7-dehydrocholesterol reductase Enzyme 3.9E-13 0.500 0.846 193
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962 191
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962 187
GTF2I P78347 general transcription factor IIi 1.00 0.500 0.808 187
TBL2 Q9Y4P3 transducin beta like 2 1.8E-04 0.538 0.731 185
GTF2IRD1 Q9UHL9 GTF2I repeat domain containing 1 0.90 0.522 0.769 180
CLIP2 Q9UDT6 CAP-Gly domain containing linker protein 2 Cellular structure 1.00 0.529 0.808 175
LIMK1 P53667 LIM domain kinase 1 Kinase 1.00 0.488 0.731 175
RFC2 P35250 replication factor C subunit 2 Enzyme 2.2E-06 0.520 0.769 175
JMJD1C Q15652 jumonji domain containing 1C 1.00 0.517 0.769 169
MBTPS2 O43462 membrane bound transcription factor peptidase, site 2 Enzyme 1.00 0.513 0.769 167
GP1BB P13224 glycoprotein Ib platelet subunit beta 0.51 0.524 0.769 164
WDR35 Q9P2L0 WD repeat domain 35 1.0E-22 0.525 0.692 160