| Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI g | DPI g | Num. diseases |
|---|---|---|---|---|---|---|---|
| PRKAR1A | P10644 | protein kinase cAMP-dependent type I regulatory subunit alpha | 1.00 | 0.401 | 0.846 | 205 | |
| GLI3 | P10071 | GLI family zinc finger 3 | 1.00 | 0.436 | 0.846 | 193 | |
| HESX1 | Q9UBX0 | HESX homeobox 1 | 8.0E-04 | 0.561 | 0.654 | 116 | |
| GLI2 | P10070 | GLI family zinc finger 2 | 0.97 | 0.446 | 0.846 | 94 | |
| OTX2 | P32243 | orthodenticle homeobox 2 | Transcription factor | 0.92 | 0.514 | 0.808 | 86 |
| SOX3 | P41225 | SRY-box transcription factor 3 | Transcription factor | 0.45 | 0.535 | 0.731 | 65 |
| POU1F1 | P28069 | POU class 1 homeobox 1 | 4.5E-02 | 0.548 | 0.654 | 64 | |
| LHX4 | Q969G2 | LIM homeobox 4 | Nucleic acid binding | 1.8E-02 | 0.621 | 0.462 | 61 |
| PROP1 | O75360 | PROP paired-like homeobox 1 | 8.8E-02 | 0.576 | 0.615 | 56 |