Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4683
Gene Symbol: NBN
NBN
nibrin 0.467 0.808 2.2E-16
Precursor Cell Lymphoblastic Leukemia Lymphoma
disease 0.630 None 1.000 1 0 2001 2011
Entrez Id: 6886
Gene Symbol: TAL1
TAL1
TAL bHLH transcription factor 1, erythroid differentiation factor 0.505 0.731 0.57
Precursor Cell Lymphoblastic Leukemia Lymphoma
disease 0.460 None 1.000 1 0 1997 2012
Entrez Id: 3981
Gene Symbol: LIG4
LIG4
DNA ligase 4 0.478 0.846 4.2E-06
Precursor Cell Lymphoblastic Leukemia Lymphoma
disease 0.410 strong 1.000 1 0 2007 2017
Entrez Id: 2078
Gene Symbol: ERG
ERG
ETS transcription factor ERG 0.453 0.808 0.96
Precursor Cell Lymphoblastic Leukemia Lymphoma
disease 0.400 None 0.909 1 0 1990 2017
Entrez Id: 7157
Gene Symbol: TP53
TP53
tumor protein p53 0.236 0.962 0.53
Precursor Cell Lymphoblastic Leukemia Lymphoma
disease 0.400 None 1.000 1 0 1991 2020
Entrez Id: 3717
Gene Symbol: JAK2
JAK2
Janus kinase 2 0.385 0.885 0.65
Precursor Cell Lymphoblastic Leukemia Lymphoma
disease 0.400 None 1.000 1 0 1997 2019
Entrez Id: 1728
Gene Symbol: NQO1
NQO1
NAD(P)H quinone dehydrogenase 1 0.434 0.885 1.2E-09
Precursor Cell Lymphoblastic Leukemia Lymphoma
disease 0.350 None 1.000 1 0 2002 2014
Entrez Id: 3716
Gene Symbol: JAK1
JAK1
Janus kinase 1 0.474 0.769 1.00
Precursor Cell Lymphoblastic Leukemia Lymphoma
disease 0.340 None 1.000 1 0 2008 2017
Entrez Id: 5925
Gene Symbol: RB1
RB1
RB transcriptional corepressor 1 0.444 0.885 1.00
Precursor Cell Lymphoblastic Leukemia Lymphoma
disease 0.320 None 1.000 1 0 1994 2013
Entrez Id: 841
Gene Symbol: CASP8
CASP8
caspase 8 0.404 0.923 3.7E-06
Precursor Cell Lymphoblastic Leukemia Lymphoma
disease 0.320 None 1.000 1 0 2006 2011
Entrez Id: 405
Gene Symbol: ARNT
ARNT
aryl hydrocarbon receptor nuclear translocator 0.575 0.692 1.00
Precursor Cell Lymphoblastic Leukemia Lymphoma
disease 0.310 None 1.000 1 0 2006 2012
Entrez Id: 22807
Gene Symbol: IKZF2
IKZF2
IKAROS family zinc finger 2 0.656 0.500 0.99
Precursor Cell Lymphoblastic Leukemia Lymphoma
disease 0.310 None 1.000 1 0 2002 2013
Entrez Id: 1571
Gene Symbol: CYP2E1
CYP2E1
cytochrome P450 family 2 subfamily E member 1 0.459 0.885 8.1E-09
Precursor Cell Lymphoblastic Leukemia Lymphoma
disease 0.310 None 1.000 1 0 2002 2007
Entrez Id: 4609
Gene Symbol: MYC
MYC
MYC proto-oncogene, bHLH transcription factor 0.344 0.923 1.00
Precursor Cell Lymphoblastic Leukemia Lymphoma
disease 0.100 None 1.000 1 0 1990 2019
Entrez Id: 3704
Gene Symbol: ITPA
ITPA
inosine triphosphatase 0.604 0.500 1.0E-07
Precursor Cell Lymphoblastic Leukemia Lymphoma
disease 0.080 None 1.000 1 0 2009 2019
Entrez Id: 4311
Gene Symbol: MME
MME
membrane metalloendopeptidase 0.407 0.808 1.5E-18
Precursor Cell Lymphoblastic Leukemia Lymphoma
disease 0.080 None 1.000 1 0 1987 2013
Entrez Id: 5781
Gene Symbol: PTPN11
PTPN11
protein tyrosine phosphatase non-receptor type 11 0.385 0.923 1.00
Precursor Cell Lymphoblastic Leukemia Lymphoma
disease 0.070 None 1.000 1 0 2004 2018
Entrez Id: 7298
Gene Symbol: TYMS
TYMS
thymidylate synthetase 0.425 0.846 0.72
Precursor Cell Lymphoblastic Leukemia Lymphoma
disease 0.050 None 0.800 1 0 2005 2018
Entrez Id: 7490
Gene Symbol: WT1
WT1
WT1 transcription factor 0.422 0.808 1.00
Precursor Cell Lymphoblastic Leukemia Lymphoma
disease 0.050 None 1.000 1 0 2004 2011
Entrez Id: 1543
Gene Symbol: CYP1A1
CYP1A1
cytochrome P450 family 1 subfamily A member 1 0.436 0.846 1.1E-17
Precursor Cell Lymphoblastic Leukemia Lymphoma
disease 0.050 None 1.000 1 0 2008 2013
Entrez Id: 8028
Gene Symbol: MLLT10
MLLT10
MLLT10 histone lysine methyltransferase DOT1L cofactor 0.551 0.462 1.00
Precursor Cell Lymphoblastic Leukemia Lymphoma
disease 0.050 None 1.000 1 0 2000 2018
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
phosphatase and tensin homolog 0.305 0.923 0.26
Precursor Cell Lymphoblastic Leukemia Lymphoma
disease 0.050 None 1.000 1 0 2003 2017
Entrez Id: 4193
Gene Symbol: MDM2
MDM2
MDM2 proto-oncogene 0.362 0.846 1.00
Precursor Cell Lymphoblastic Leukemia Lymphoma
disease 0.050 None 1.000 1 0 1999 2015
Entrez Id: 3574
Gene Symbol: IL7
IL7
interleukin 7 0.464 0.808 0.93
Precursor Cell Lymphoblastic Leukemia Lymphoma
disease 0.040 None 1.000 1 0 1990 2017
Entrez Id: 5981
Gene Symbol: RFC1
RFC1
replication factor C subunit 1 0.541 0.808 0.97
Precursor Cell Lymphoblastic Leukemia Lymphoma
disease 0.040 None 1.000 1 0 2008 2019