Source: LHGDN

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
prostaglandin-endoperoxide synthase 2 0.314 0.962 1.00
CUI: C0025500
Disease: Mesothelioma
Mesothelioma
disease 0.020 None 1.000 1 0 2008 2013
Entrez Id: 7157
Gene Symbol: TP53
TP53
tumor protein p53 0.236 0.962 0.53
CUI: C0025500
Disease: Mesothelioma
Mesothelioma
disease 0.300 None 0.871 1 0 1991 2018
Entrez Id: 2247
Gene Symbol: FGF2
FGF2
fibroblast growth factor 2 0.383 0.923 1.8E-02
CUI: C0025500
Disease: Mesothelioma
Mesothelioma
disease 0.330 None 1.000 1 0 2004 2014
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
glutathione S-transferase mu 1 0.380 0.923 2.1E-03
CUI: C0025500
Disease: Mesothelioma
Mesothelioma
disease 0.310 None 1.000 1 0 2007 2007
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
hypoxia inducible factor 1 subunit alpha 0.327 0.923 0.98
CUI: C0025500
Disease: Mesothelioma
Mesothelioma
disease 0.010 None 1.000 1 0 2008 2008
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
KRAS proto-oncogene, GTPase 0.320 0.923 7.9E-04
CUI: C0025500
Disease: Mesothelioma
Mesothelioma
disease 0.020 None 1.000 1 0 2000 2007
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
matrix metallopeptidase 9 0.305 0.923 1.9E-17
CUI: C0025500
Disease: Mesothelioma
Mesothelioma
disease 0.040 None 1.000 1 0 2007 2018
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
superoxide dismutase 2 0.379 0.923 0.15
CUI: C0025500
Disease: Mesothelioma
Mesothelioma
disease 0.320 None 0.750 1 0 1998 2007
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
signal transducer and activator of transcription 3 0.320 0.923 1.00
CUI: C0025500
Disease: Mesothelioma
Mesothelioma
disease 0.040 None 1.000 1 0 2007 2018
Entrez Id: 836
Gene Symbol: CASP3
CASP3
caspase 3 0.351 0.923 0.10
CUI: C0025500
Disease: Mesothelioma
Mesothelioma
disease 0.050 None 1.000 1 0 2005 2017
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
cyclin dependent kinase inhibitor 2A 0.300 0.885 0.39
CUI: C0025500
Disease: Mesothelioma
Mesothelioma
disease 0.600 None 0.965 4 0 1995 2019
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
epidermal growth factor receptor 0.295 0.885 0.37
CUI: C0025500
Disease: Mesothelioma
Mesothelioma
disease 0.400 None 0.833 3 0 1994 2019
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
secreted phosphoprotein 1 0.353 0.885 2.1E-06
CUI: C0025500
Disease: Mesothelioma
Mesothelioma
disease 0.380 None 1.000 3 0 2005 2017
Entrez Id: 4771
Gene Symbol: NF2
NF2
neurofibromin 2 0.468 0.885 1.00
CUI: C0025500
Disease: Mesothelioma
Mesothelioma
disease 0.400 None 1.000 2 0 1995 2020
Entrez Id: 2475
Gene Symbol: MTOR
MTOR
mechanistic target of rapamycin kinase 0.343 0.885 1.00
CUI: C0025500
Disease: Mesothelioma
Mesothelioma
disease 0.320 None 1.000 1 0 2008 2011
Entrez Id: 3791
Gene Symbol: KDR
KDR
kinase insert domain receptor 0.378 0.885 1.00
CUI: C0025500
Disease: Mesothelioma
Mesothelioma
disease 0.020 None 1.000 1 0 2001 2009
Entrez Id: 4254
Gene Symbol: KITLG
KITLG
KIT ligand 0.473 0.885 0.85
CUI: C0025500
Disease: Mesothelioma
Mesothelioma
disease 0.010 None 1.000 1 0 2004 2004
Entrez Id: 4582
Gene Symbol: MUC1
MUC1
mucin 1, cell surface associated 0.384 0.885 1.9E-02
CUI: C0025500
Disease: Mesothelioma
Mesothelioma
disease 0.330 None 0.667 1 0 2008 2016
Entrez Id: 5970
Gene Symbol: RELA
RELA
RELA proto-oncogene, NF-kB subunit 0.406 0.885 1.00
CUI: C0025500
Disease: Mesothelioma
Mesothelioma
disease 0.010 None 1.000 1 0 2007 2007
Entrez Id: 6714
Gene Symbol: SRC
SRC
SRC proto-oncogene, non-receptor tyrosine kinase 0.467 0.885 1.00
CUI: C0025500
Disease: Mesothelioma
Mesothelioma
disease 0.020 None 1.000 1 0 2007 2012
Entrez Id: 1028
Gene Symbol: CDKN1C
CDKN1C
cyclin dependent kinase inhibitor 1C 0.456 0.846 0.82
CUI: C0025500
Disease: Mesothelioma
Mesothelioma
disease 0.010 None 1.000 1 0 2004 2004
Entrez Id: 2272
Gene Symbol: FHIT
FHIT
fragile histidine triad diadenosine triphosphatase 0.444 0.846 5.7E-03
CUI: C0025500
Disease: Mesothelioma
Mesothelioma
disease 0.310 None 1.000 1 0 2004 2008
Entrez Id: 673
Gene Symbol: BRAF
BRAF
B-Raf proto-oncogene, serine/threonine kinase 0.319 0.846 1.00
CUI: C0025500
Disease: Mesothelioma
Mesothelioma
disease 0.010 None 1.000 1 0 2004 2004
Entrez Id: 8837
Gene Symbol: CFLAR
CFLAR
CASP8 and FADD like apoptosis regulator 0.485 0.846 1.00
CUI: C0025500
Disease: Mesothelioma
Mesothelioma
disease 0.010 None 1.000 1 0 2004 2004
Entrez Id: 10413
Gene Symbol: YAP1
YAP1
Yes associated protein 1 0.432 0.808 1.00
CUI: C0025500
Disease: Mesothelioma
Mesothelioma
disease 0.020 None 1.000 1 0 2008 2017