| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
BRCA1 associated RING domain 1 | 0.597 | 0.538 | 1.4E-24 |
|
disease | 0.200 | None | 0.875 | 3 | 0 | 1998 | 2019 | ||||||||
|
X-ray repair cross complementing 2 | 0.512 | 0.731 | 4.0E-07 |
|
disease | 0.200 | None | 0.800 | 1 | 0 | 2005 | 2016 | ||||||||
|
checkpoint kinase 2 | 0.460 | 0.808 | 1.2E-24 |
|
disease | 0.200 | None | 0.769 | 1 | 0 | 2002 | 2019 | ||||||||
|
HNF1 homeobox B | 0.473 | 0.808 | 1.00 |
|
disease | 0.190 | None | 1.000 | 3 | 0 | 2005 | 2017 | ||||||||
|
ATM serine/threonine kinase | 0.374 | 0.885 | 5.6E-47 |
|
disease | 0.170 | None | 0.857 | 1 | 0 | 1999 | 2019 | ||||||||
|
fibroblast growth factor receptor 2 | 0.380 | 0.808 | 1.00 |
|
disease | 0.160 | None | 1.000 | 1 | 0 | 2007 | 2017 | ||||||||
|
nibrin | 0.467 | 0.808 | 2.2E-16 |
|
disease | 0.140 | None | 0.500 | 2 | 0 | 2007 | 2019 | ||||||||
|
RELA proto-oncogene, NF-kB subunit | 0.406 | 0.885 | 1.00 |
|
disease | 0.130 | None | 1.000 | 2 | 0 | 2007 | 2017 | ||||||||
|
WT1 transcription factor | 0.422 | 0.808 | 1.00 |
|
disease | 0.130 | None | 1.000 | 1 | 0 | 1994 | 2015 | ||||||||
|
dicer 1, ribonuclease III | 0.446 | 0.846 | 1.00 |
|
disease | 0.130 | None | 1.000 | 1 | 0 | 2004 | 2013 | ||||||||
|
abraxas 1, BRCA1 A complex subunit | 0.760 | 0.269 | 5.1E-07 |
|
disease | 0.110 | None | 1.000 | 1 | 0 | 2009 | 2009 | ||||||||
|
mitogen-activated protein kinase kinase kinase 1 | 0.538 | 0.731 | 1.00 |
|
disease | 0.110 | None | 1.000 | 1 | 0 | 2004 | 2004 | ||||||||
|
vascular endothelial growth factor A | 0.266 | 0.923 | 2.4E-05 |
|
disease | 0.100 | None | 0.973 | 10 | 0 | 1996 | 2019 | ||||||||
|
prostaglandin-endoperoxide synthase 2 | 0.314 | 0.962 | 1.00 |
|
disease | 0.100 | None | 1.000 | 6 | 0 | 2001 | 2019 | ||||||||
|
ERCC excision repair 1, endonuclease non-catalytic subunit | 0.445 | 0.846 | 1.6E-07 |
|
disease | 0.100 | None | 0.944 | 4 | 0 | 1997 | 2019 | ||||||||
|
cyclin dependent kinase inhibitor 1A | 0.403 | 0.769 | 1.9E-03 |
|
disease | 0.100 | None | 1.000 | 4 | 0 | 1999 | 2015 | ||||||||
|
cyclin dependent kinase inhibitor 2A | 0.300 | 0.885 | 0.39 |
|
disease | 0.100 | None | 0.967 | 4 | 0 | 1995 | 2019 | ||||||||
|
transforming growth factor beta 1 | 0.287 | 0.962 | 3.7E-02 |
|
disease | 0.100 | None | 1.000 | 4 | 0 | 1992 | 2019 | ||||||||
|
androgen receptor | 0.351 | 0.846 | 0.99 |
|
disease | 0.100 | None | 0.895 | 4 | 0 | 1999 | 2019 | ||||||||
|
matrix metallopeptidase 9 | 0.305 | 0.923 | 1.9E-17 |
|
disease | 0.100 | None | 1.000 | 4 | 0 | 1998 | 2018 | ||||||||
|
estrogen receptor 2 | 0.400 | 0.923 | 4.5E-08 |
|
disease | 0.100 | None | 1.000 | 3 | 0 | 2003 | 2019 | ||||||||
|
matrix metallopeptidase 2 | 0.333 | 0.923 | 0.84 |
|
disease | 0.100 | None | 1.000 | 3 | 0 | 2002 | 2019 | ||||||||
|
hypoxia inducible factor 1 subunit alpha | 0.327 | 0.923 | 0.98 |
|
disease | 0.100 | None | 0.964 | 3 | 0 | 2001 | 2020 | ||||||||
|
protein tyrosine kinase 2 | 0.497 | 0.808 | 1.00 |
|
disease | 0.100 | None | 1.000 | 3 | 0 | 2004 | 2019 | ||||||||
|
secreted phosphoprotein 1 | 0.353 | 0.885 | 2.1E-06 |
|
disease | 0.100 | None | 1.000 | 3 | 0 | 2002 | 2019 |