| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
APC regulator of WNT signaling pathway | 0.373 | 0.962 | 1.00 |
|
disease | 0.800 | strong | 0.972 | 6 | 14 | 1990 | 2020 | ||||||||
|
mutL homolog 1 | 0.399 | 0.808 | 3.4E-05 |
|
disease | 0.800 | strong | 0.973 | 3 | 2 | 1993 | 2020 | ||||||||
|
mutS homolog 2 | 0.406 | 0.808 | 0.90 |
|
disease | 0.800 | strong | 0.971 | 0 | 2 | 1993 | 2020 | ||||||||
|
NRAS proto-oncogene, GTPase | 0.390 | 0.808 | 0.49 |
|
disease | 0.800 | strong | 0.966 | 0 | 1 | 1993 | 2020 | ||||||||
|
transcription factor 7 like 2 | 0.485 | 0.846 | 1.00 |
|
disease | 0.700 | None | 0.925 | 5 | 2 | 1999 | 2019 | ||||||||
|
SMAD family member 3 | 0.415 | 0.923 | 0.80 |
|
disease | 0.700 | None | 0.941 | 1 | 1 | 1998 | 2019 | ||||||||
|
matrix metallopeptidase 2 | 0.333 | 0.923 | 0.84 |
|
disease | 0.700 | None | 1.000 | 1 | 1 | 1992 | 2019 | ||||||||
|
B-Raf proto-oncogene, serine/threonine kinase | 0.319 | 0.846 | 1.00 |
|
disease | 0.700 | None | 0.976 | 0 | 5 | 2002 | 2020 | ||||||||
|
checkpoint kinase 2 | 0.460 | 0.808 | 1.2E-24 |
|
disease | 0.700 | limited | 0.885 | 0 | 1 | 2003 | 2019 | ||||||||
|
BUB1 mitotic checkpoint serine/threonine kinase | 0.528 | 0.731 | 4.9E-09 |
|
disease | 0.700 | None | 1.000 | 0 | 1 | 2000 | 2018 | ||||||||
|
tumor protein p53 | 0.236 | 0.962 | 0.53 |
|
disease | 0.700 | None | 0.947 | 0 | 7 | 1989 | 2020 | ||||||||
|
catenin beta 1 | 0.303 | 0.885 | 1.00 |
|
disease | 0.700 | None | 0.983 | 0 | 3 | 1997 | 2020 | ||||||||
|
DCC netrin 1 receptor | 0.471 | 0.808 | 0.99 |
|
disease | 0.700 | None | 0.946 | 0 | 1 | 1990 | 2019 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 0.292 | 0.923 | 1.00 |
|
disease | 0.700 | None | 0.985 | 0 | 5 | 2002 | 2020 | ||||||||
|
fibroblast growth factor receptor 3 | 0.391 | 0.846 | 1.6E-05 |
|
disease | 0.660 | None | 1.000 | 0 | 8 | 2000 | 2018 | ||||||||
|
Kruppel like factor 5 | 0.534 | 0.769 | 0.82 |
|
disease | 0.640 | None | 1.000 | 2 | 1 | 2011 | 2019 | ||||||||
|
E1A binding protein p300 | 0.459 | 0.846 | 1.00 |
|
disease | 0.640 | None | 1.000 | 1 | 4 | 1996 | 2017 | ||||||||
|
mutY DNA glycosylase | 0.521 | 0.769 | 1.3E-18 |
|
disease | 0.500 | strong | 0.947 | 22 | 9 | 2002 | 2019 | ||||||||
|
SMAD family member 7 | 0.470 | 0.769 | 0.55 |
|
disease | 0.500 | None | 0.984 | 18 | 8 | 2001 | 2019 | ||||||||
|
gremlin 1, DAN family BMP antagonist | 0.508 | 0.808 | 0.47 |
|
disease | 0.500 | None | 0.957 | 6 | 4 | 2003 | 2019 | ||||||||
|
bone morphogenetic protein 4 | 0.422 | 0.808 | 0.96 |
|
disease | 0.500 | None | 0.952 | 2 | 1 | 2008 | 2020 | ||||||||
|
cadherin 1 | 0.401 | 0.808 | 0.15 |
|
disease | 0.500 | None | 0.939 | 2 | 2 | 1997 | 2020 | ||||||||
|
transforming growth factor beta 1 | 0.287 | 0.962 | 3.7E-02 |
|
disease | 0.500 | None | 0.971 | 1 | 2 | 1995 | 2020 | ||||||||
|
peroxisome proliferator activated receptor gamma | 0.358 | 0.885 | 2.9E-02 |
|
disease | 0.500 | None | 0.938 | 0 | 4 | 2000 | 2019 | ||||||||
|
PMS1 homolog 2, mismatch repair system component | 0.484 | 0.808 | 4.5E-27 |
|
disease | 0.500 | strong | 0.967 | 0 | 1 | 1998 | 2020 |