| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
peroxisome proliferator activated receptor gamma | 0.358 | 0.885 | 2.9E-02 |
|
disease | 1.000 | None | 0.960 | 0 | 0 | 1997 | 2020 | ||||||||
|
melanocortin 4 receptor | 0.535 | 0.692 | 9.2E-04 |
|
disease | 1.000 | None | 0.961 | 0 | 0 | 1997 | 2020 | ||||||||
|
proopiomelanocortin | 0.356 | 0.846 | 1.2E-04 |
|
disease | 0.900 | strong | 0.959 | 0 | 0 | 1996 | 2020 | ||||||||
|
agouti related neuropeptide | 0.488 | 0.769 | 7.0E-04 |
|
disease | 0.700 | None | 0.938 | 0 | 0 | 1997 | 2019 | ||||||||
|
SH2B adaptor protein 1 | 0.566 | 0.731 | 0.97 |
|
disease | 0.700 | moderate | 0.906 | 0 | 0 | 2009 | 2020 | ||||||||
|
uncoupling protein 3 | 0.619 | 0.577 | 9.6E-10 |
|
disease | 0.700 | None | 0.907 | 0 | 0 | 1998 | 2018 | ||||||||
|
leptin | 0.349 | 0.846 | 0.46 |
|
disease | 0.700 | None | 0.952 | 0 | 0 | 1973 | 2020 | ||||||||
|
leptin receptor | 0.433 | 0.808 | 0.99 |
|
disease | 0.700 | None | 0.930 | 0 | 0 | 1966 | 2019 | ||||||||
|
SIM bHLH transcription factor 1 | 0.626 | 0.654 | 1.00 |
|
disease | 0.700 | strong | 0.955 | 0 | 0 | 1998 | 2019 | ||||||||
|
ectonucleotide pyrophosphatase/phosphodiesterase 1 | 0.498 | 0.808 | 5.0E-08 |
|
disease | 0.700 | moderate | 0.786 | 0 | 0 | 2001 | 2019 | ||||||||
|
proprotein convertase subtilisin/kexin type 1 | 0.548 | 0.615 | 2.7E-09 |
|
disease | 0.700 | None | 0.857 | 0 | 0 | 1997 | 2018 | ||||||||
|
nuclear receptor subfamily 0 group B member 2 | 0.474 | 0.808 | 8.3E-06 |
|
disease | 0.690 | limited | 1.000 | 0 | 0 | 2001 | 2020 | ||||||||
|
Bardet-Biedl syndrome 4 | 0.647 | 0.615 | 1.5E-16 |
|
disease | 0.660 | strong | 1.000 | 0 | 0 | 2001 | 2019 | ||||||||
|
McKusick-Kaufman syndrome | 0.566 | 0.692 | 2.1E-09 |
|
disease | 0.660 | strong | 0.833 | 0 | 0 | 2000 | 2013 | ||||||||
|
Bardet-Biedl syndrome 1 | 0.593 | 0.692 | 3.4E-12 |
|
disease | 0.620 | strong | 1.000 | 0 | 0 | 2002 | 2013 | ||||||||
|
insulin | 0.445 | 0.923 | 0.30 |
|
disease | 0.500 | None | 0.895 | 0 | 0 | 1989 | 2019 | ||||||||
|
adrenoceptor beta 3 | 0.533 | 0.731 | 2.5E-07 |
|
disease | 0.500 | None | 0.905 | 0 | 0 | 1995 | 2019 | ||||||||
|
adrenoceptor beta 2 | 0.442 | 0.923 | 0.53 |
|
disease | 0.500 | None | 0.884 | 0 | 0 | 1997 | 2019 | ||||||||
|
ghrelin and obestatin prepropeptide | 0.517 | 0.769 | 1.4E-11 |
|
disease | 0.500 | None | 0.923 | 0 | 0 | 2001 | 2019 | ||||||||
|
CART prepropeptide | 0.576 | 0.692 | 9.4E-02 |
|
disease | 0.500 | None | 0.917 | 0 | 0 | 1999 | 2017 | ||||||||
|
FTO alpha-ketoglutarate dependent dioxygenase | 0.486 | 0.885 | 8.4E-08 |
|
disease | 0.500 | None | 0.953 | 0 | 0 | 2007 | 2020 | ||||||||
|
apolipoprotein E | 0.338 | 0.962 | 1.9E-03 |
|
disease | 0.500 | None | 0.974 | 0 | 0 | 1988 | 2019 | ||||||||
|
GNAS complex locus | 0.420 | 0.885 | 0.68 |
|
disease | 0.490 | None | 1.000 | 0 | 0 | 2003 | 2018 | ||||||||
|
adenylate cyclase 3 | 0.678 | 0.615 | 2.0E-11 |
|
disease | 0.490 | None | 1.000 | 0 | 0 | 2008 | 2018 | ||||||||
|
protein kinase cAMP-dependent type I regulatory subunit alpha | 0.401 | 0.846 | 1.00 |
|
disease | 0.460 | None | 1.000 | 0 | 0 | 2006 | 2019 |