Source: HPO

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5663
Gene Symbol: PSEN1
PSEN1 		presenilin 1 0.469 0.846 0.97
CUI: C0333463
Disease: Senile Plaques
Senile Plaques 		disease 0.200 None 1.000 0 0 1996 2018
Entrez Id: 5621
Gene Symbol: PRNP
PRNP 		prion protein 0.445 0.923 6.3E-04
CUI: C0333463
Disease: Senile Plaques
Senile Plaques 		disease 0.200 None 0.900 0 0 1991 2020
Entrez Id: 348
Gene Symbol: APOE
APOE 		apolipoprotein E 0.338 0.962 1.9E-03
CUI: C0333463
Disease: Senile Plaques
Senile Plaques 		disease 0.200 None 0.921 0 0 1993 2019
Entrez Id: 4137
Gene Symbol: MAPT
MAPT 		microtubule associated protein tau 0.446 0.923 6.0E-03
CUI: C0333463
Disease: Senile Plaques
Senile Plaques 		disease 0.200 None 1.000 0 0 1993 2019
Entrez Id: 54209
Gene Symbol: TREM2
TREM2 		triggering receptor expressed on myeloid cells 2 0.519 0.769 3.3E-09
CUI: C0333463
Disease: Senile Plaques
Senile Plaques 		disease 0.130 None 0.667 0 0 2018 2019
Entrez Id: 5664
Gene Symbol: PSEN2
PSEN2 		presenilin 2 0.550 0.654 5.4E-04
CUI: C0333463
Disease: Senile Plaques
Senile Plaques 		disease 0.120 None 1.000 0 0 2002 2004
Entrez Id: 10347
Gene Symbol: ABCA7
ABCA7 		ATP binding cassette subfamily A member 7 0.644 0.577 2.1E-55
CUI: C0333463
Disease: Senile Plaques
Senile Plaques 		disease 0.110 None 1.000 0 0 2015 2015
Entrez Id: 2896
Gene Symbol: GRN
GRN 		granulin precursor 0.435 0.846 7.0E-02
CUI: C0333463
Disease: Senile Plaques
Senile Plaques 		disease 0.110 None 1.000 0 0 2017 2017
Entrez Id: 54664
Gene Symbol: TMEM106B
TMEM106B 		transmembrane protein 106B 0.590 0.462 0.33
CUI: C0333463
Disease: Senile Plaques
Senile Plaques 		disease 0.100 None 0 0
Entrez Id: 25978
Gene Symbol: CHMP2B
CHMP2B 		charged multivesicular body protein 2B 0.543 0.731 4.6E-06
CUI: C0333463
Disease: Senile Plaques
Senile Plaques 		disease 0.100 None 0 0
Entrez Id: 203228
Gene Symbol: C9orf72
C9orf72 		C9orf72-SMCR8 complex subunit 0.496 0.769 1.1E-06
CUI: C0333463
Disease: Senile Plaques
Senile Plaques 		disease 0.100 None 0 0
Entrez Id: 7415
Gene Symbol: VCP
VCP 		valosin containing protein 0.469 0.923 1.00
CUI: C0333463
Disease: Senile Plaques
Senile Plaques 		disease 0.100 None 0 0