Source: GENOMICS_ENGLAND

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 351
Gene Symbol: APP
APP 		amyloid beta precursor protein 0.422 0.846 4.7E-02
CUI: C0497327
Disease: Dementia
Dementia 		disease 0.700 strong 0.964 2 0 1993 2020
Entrez Id: 54209
Gene Symbol: TREM2
TREM2 		triggering receptor expressed on myeloid cells 2 0.519 0.769 3.3E-09
CUI: C0497327
Disease: Dementia
Dementia 		disease 0.700 strong 1.000 1 0 2005 2020
Entrez Id: 5664
Gene Symbol: PSEN2
PSEN2 		presenilin 2 0.550 0.654 5.4E-04
CUI: C0497327
Disease: Dementia
Dementia 		disease 0.500 strong 1.000 2 0 1997 2018
Entrez Id: 5621
Gene Symbol: PRNP
PRNP 		prion protein 0.445 0.923 6.3E-04
CUI: C0497327
Disease: Dementia
Dementia 		disease 0.500 strong 0.958 2 0 1991 2019
Entrez Id: 4854
Gene Symbol: NOTCH3
NOTCH3 		notch receptor 3 0.435 0.808 0.41
CUI: C0497327
Disease: Dementia
Dementia 		disease 0.500 strong 1.000 1 0 1996 2017
Entrez Id: 1471
Gene Symbol: CST3
CST3 		cystatin C 0.436 0.808 3.9E-03
CUI: C0497327
Disease: Dementia
Dementia 		disease 0.460 limited 1.000 0 0 1996 2019
Entrez Id: 5654
Gene Symbol: HTRA1
HTRA1 		HtrA serine peptidase 1 0.532 0.692 4.9E-04
CUI: C0497327
Disease: Dementia
Dementia 		disease 0.400 strong 1.000 1 0 2014 2014
Entrez Id: 2521
Gene Symbol: FUS
FUS 		FUS RNA binding protein 0.470 0.846 1.00
CUI: C0497327
Disease: Dementia
Dementia 		disease 0.380 None 1.000 1 0 2009 2017
Entrez Id: 7305
Gene Symbol: TYROBP
TYROBP 		transmembrane immune signaling adaptor TYROBP 0.573 0.769 0.20
CUI: C0497327
Disease: Dementia
Dementia 		disease 0.360 strong 1.000 2 0 2000 2018
Entrez Id: 1436
Gene Symbol: CSF1R
CSF1R 		colony stimulating factor 1 receptor 0.448 0.808 0.13
CUI: C0497327
Disease: Dementia
Dementia 		disease 0.330 strong 1.000 1 0 2013 2019
Entrez Id: 1282
Gene Symbol: COL4A1
COL4A1 		collagen type IV alpha 1 chain 0.484 0.731 1.00
CUI: C0497327
Disease: Dementia
Dementia 		disease 0.310 strong 1.000 1 0 2007 2016