| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
transient receptor potential cation channel subfamily V member 1 | 0.446 | 0.885 | 1.0E-16 |
|
phenotype | 0.400 | None | 1.000 | 4 | 0 | 2002 | 2019 | ||||||||
|
tumor necrosis factor | 0.231 | 0.962 | 0.80 |
|
phenotype | 0.330 | None | 1.000 | 11 | 0 | 1995 | 2019 | ||||||||
|
interleukin 1 beta | 0.276 | 0.962 | 0.13 |
|
phenotype | 0.320 | None | 1.000 | 6 | 0 | 1995 | 2017 | ||||||||
|
tachykinin precursor 1 | 0.424 | 0.923 | 0.75 |
|
phenotype | 0.310 | None | 1.000 | 9 | 0 | 1996 | 2017 | ||||||||
|
interleukin 1 receptor antagonist | 0.373 | 0.923 | 3.1E-02 |
|
phenotype | 0.310 | None | 1.000 | 4 | 0 | 1996 | 2017 | ||||||||
|
protein kinase C epsilon | 0.597 | 0.692 | 1.00 |
|
phenotype | 0.310 | None | 1.000 | 3 | 0 | 2001 | 2019 | ||||||||
|
prepronociceptin | 0.603 | 0.577 | 1.5E-02 |
|
phenotype | 0.310 | None | 1.000 | 2 | 0 | 2003 | 2015 | ||||||||
|
interleukin 10 | 0.281 | 0.923 | 5.9E-03 |
|
phenotype | 0.310 | None | 1.000 | 2 | 0 | 1995 | 2007 | ||||||||
|
high mobility group box 1 | 0.368 | 0.923 | 0.82 |
|
phenotype | 0.310 | None | 1.000 | 1 | 0 | 2016 | 2018 | ||||||||
|
glial cell derived neurotrophic factor | 0.434 | 0.885 | 0.20 |
|
phenotype | 0.310 | None | 1.000 | 1 | 0 | 2010 | 2014 | ||||||||
|
C-C motif chemokine ligand 2 | 0.321 | 0.962 | 0.61 |
|
phenotype | 0.310 | None | 1.000 | 1 | 0 | 2007 | 2017 | ||||||||
|
opioid receptor mu 1 | 0.457 | 0.808 | 7.9E-11 |
|
phenotype | 0.310 | None | 1.000 | 1 | 0 | 2008 | 2017 | ||||||||
|
purinergic receptor P2X 2 | 0.585 | 0.769 | 9.7E-13 |
|
phenotype | 0.310 | None | 1.000 | 1 | 0 | 2009 | 2018 | ||||||||
|
mitogen-activated protein kinase 8 | 0.397 | 0.885 | 1.00 |
|
phenotype | 0.310 | None | 1.000 | 1 | 0 | 2016 | 2017 | ||||||||
|
purinergic receptor P2X 3 | 0.565 | 0.769 | 1.0E-06 |
|
phenotype | 0.310 | None | 1.000 | 1 | 0 | 2009 | 2018 | ||||||||
|
kininogen 1 | 0.481 | 0.885 | 3.2E-10 |
|
phenotype | 0.300 | None | 1.000 | 17 | 0 | 1988 | 2011 | ||||||||
|
calcitonin related polypeptide alpha | 0.416 | 0.923 | 1.6E-02 |
|
phenotype | 0.300 | None | 1.000 | 4 | 0 | 2003 | 2016 | ||||||||
|
bradykinin receptor B2 | 0.585 | 0.808 | 0.12 |
|
phenotype | 0.300 | None | 1.000 | 3 | 0 | 2008 | 2010 | ||||||||
|
interleukin 6 | 0.248 | 0.962 | 0.32 |
|
phenotype | 0.300 | None | 1.000 | 3 | 0 | 1995 | 2008 | ||||||||
|
transient receptor potential cation channel subfamily A member 1 | 0.546 | 0.846 | 7.2E-35 |
|
phenotype | 0.300 | None | 1.000 | 3 | 0 | 2008 | 2013 | ||||||||
|
bradykinin receptor B1 | 0.619 | 0.731 | 4.7E-03 |
|
phenotype | 0.300 | None | 1.000 | 3 | 0 | 2008 | 2010 | ||||||||
|
calcium voltage-gated channel auxiliary subunit alpha2delta 1 | 0.641 | 0.500 | 1.00 |
|
phenotype | 0.300 | None | 1.000 | 3 | 0 | 2001 | 2013 | ||||||||
|
C-X-C motif chemokine ligand 8 | 0.310 | 0.962 | 2.7E-04 |
|
phenotype | 0.300 | None | 1.000 | 2 | 0 | 1995 | 1999 | ||||||||
|
protein kinase C gamma | 0.617 | 0.500 | 1.00 |
|
phenotype | 0.300 | None | 1.000 | 2 | 0 | 2009 | 2016 | ||||||||
|
nitric oxide synthase 2 | 0.364 | 0.923 | 4.0E-15 |
|
phenotype | 0.300 | None | 1.000 | 2 | 0 | 2008 | 2009 |