| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
tet methylcytosine dioxygenase 2 | 0.458 | 0.808 | 4.3E-54 |
|
group | 0.800 | limited | 0.973 | 0 | 0 | 2009 | 2020 | ||||||||
|
GATA binding protein 2 | 0.496 | 0.654 | 0.98 |
|
group | 0.800 | None | 0.976 | 0 | 0 | 2002 | 2019 | ||||||||
|
splicing factor 3b subunit 1 | 0.511 | 0.731 | 1.00 |
|
group | 0.800 | limited | 0.971 | 0 | 0 | 2011 | 2020 | ||||||||
|
ASXL transcriptional regulator 1 | 0.482 | 0.808 | 1.3E-14 |
|
group | 0.800 | None | 0.960 | 0 | 0 | 2009 | 2019 | ||||||||
|
SBDS ribosome maturation factor | 0.601 | 0.692 | 6.2E-05 |
|
group | 0.620 | strong | 1.000 | 0 | 0 | 2009 | 2017 | ||||||||
|
MPL proto-oncogene, thrombopoietin receptor | 0.510 | 0.692 | 4.1E-09 |
|
group | 0.500 | None | 1.000 | 0 | 0 | 1998 | 2020 | ||||||||
|
protein tyrosine phosphatase non-receptor type 11 | 0.385 | 0.923 | 1.00 |
|
group | 0.500 | None | 1.000 | 0 | 0 | 2001 | 2017 | ||||||||
|
FA complementation group B | 0.468 | 0.769 | 1.00 |
|
group | 0.500 | strong | 0.963 | 0 | 0 | 1984 | 2020 | ||||||||
|
tumor protein p53 | 0.236 | 0.962 | 0.53 |
|
group | 0.500 | None | 0.983 | 0 | 0 | 1991 | 2020 | ||||||||
|
serine and arginine rich splicing factor 2 | 0.561 | 0.731 | 0.48 |
|
group | 0.500 | None | 1.000 | 0 | 0 | 2012 | 2020 | ||||||||
|
RUNX family transcription factor 1 | 0.425 | 0.808 | 0.65 |
|
group | 0.500 | None | 1.000 | 0 | 0 | 1993 | 2020 | ||||||||
|
ATRX chromatin remodeler | 0.452 | 0.808 | 1.00 |
|
group | 0.470 | None | 1.000 | 0 | 0 | 2003 | 2019 | ||||||||
|
RAD51 recombinase | 0.447 | 0.846 | 2.7E-02 |
|
group | 0.460 | moderate | 1.000 | 0 | 0 | 2011 | 2017 | ||||||||
|
calreticulin | 0.413 | 0.923 | 0.89 |
|
group | 0.420 | None | 1.000 | 0 | 0 | 2015 | 2020 | ||||||||
|
X-ray repair cross complementing 2 | 0.512 | 0.731 | 4.0E-07 |
|
group | 0.420 | strong | 1.000 | 0 | 0 | 2017 | 2019 | ||||||||
|
ERCC excision repair 4, endonuclease catalytic subunit | 0.468 | 0.846 | 1.4E-12 |
|
group | 0.410 | strong | 0.500 | 0 | 0 | 2017 | 2017 | ||||||||
|
SH2B adaptor protein 3 | 0.527 | 0.692 | 1.0E-04 |
|
group | 0.410 | None | 1.000 | 0 | 0 | 2019 | 2019 | ||||||||
|
BRCA2 DNA repair associated | 0.379 | 0.846 | 2.4E-25 |
|
group | 0.410 | strong | 1.000 | 0 | 0 | 2017 | 2017 | ||||||||
|
FA complementation group D2 | 0.479 | 0.885 | 1.1E-30 |
|
group | 0.410 | strong | 1.000 | 0 | 0 | 2005 | 2017 | ||||||||
|
RAD51 paralog C | 0.533 | 0.692 | 6.2E-14 |
|
group | 0.400 | moderate | 1.000 | 0 | 0 | 2017 | 2017 | ||||||||
|
SLX4 structure-specific endonuclease subunit | 0.565 | 0.731 | 1.6E-22 |
|
group | 0.400 | strong | 1.000 | 0 | 0 | 2017 | 2017 | ||||||||
|
FA complementation group L | 0.551 | 0.731 | 5.9E-23 |
|
group | 0.400 | strong | 1.000 | 0 | 0 | 2017 | 2017 | ||||||||
|
FA complementation group G | 0.556 | 0.769 | 2.5E-14 |
|
group | 0.400 | strong | 1.000 | 0 | 0 | 2017 | 2017 | ||||||||
|
FA complementation group M | 0.543 | 0.731 | 2.4E-15 |
|
group | 0.400 | moderate | 1.000 | 0 | 0 | 2017 | 2017 | ||||||||
|
BRCA1 interacting protein C-terminal helicase 1 | 0.507 | 0.731 | 6.2E-17 |
|
group | 0.400 | strong | 1.000 | 0 | 0 | 2017 | 2017 |