| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
smoothened, frizzled class receptor | 0.489 | 0.731 | 4.3E-07 |
|
disease | 0.700 | None | 0.955 | 3 | 2 | 1998 | 2019 | ||||||||
|
RAS p21 protein activator 1 | 0.481 | 0.885 | 1.00 |
|
disease | 0.610 | None | 1.000 | 0 | 0 | 2001 | 2001 | ||||||||
|
melanocortin 1 receptor | 0.524 | 0.808 | 8.1E-11 |
|
disease | 0.500 | None | 1.000 | 1 | 1 | 1999 | 2015 | ||||||||
|
tumor protein p53 | 0.236 | 0.962 | 0.53 |
|
disease | 0.500 | None | 0.938 | 1 | 1 | 1992 | 2019 | ||||||||
|
patched 1 | 0.398 | 0.885 | 1.00 |
|
disease | 0.500 | None | 0.942 | 0 | 0 | 1994 | 2020 | ||||||||
|
BRCA1 associated protein 1 | 0.454 | 0.731 | 0.99 |
|
disease | 0.460 | None | 1.000 | 1 | 1 | 2015 | 2019 | ||||||||
|
patched 2 | 0.563 | 0.692 | 3.4E-16 |
|
disease | 0.460 | None | 1.000 | 0 | 0 | 1999 | 2018 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 0.292 | 0.923 | 1.00 |
|
disease | 0.450 | None | 1.000 | 0 | 0 | 2009 | 2019 | ||||||||
|
SUFU negative regulator of hedgehog signaling | 0.493 | 0.769 | 1.00 |
|
disease | 0.440 | None | 0.750 | 0 | 0 | 2005 | 2018 | ||||||||
|
CLPTM1 like | 0.551 | 0.654 | 4.4E-05 |
|
disease | 0.430 | None | 1.000 | 2 | 1 | 2009 | 2015 | ||||||||
|
solute carrier family 45 member 2 | 0.626 | 0.538 | 1.7E-06 |
|
disease | 0.420 | None | 1.000 | 0 | 0 | 2009 | 2014 | ||||||||
|
XPA, DNA damage recognition and repair factor | 0.520 | 0.846 | 7.9E-05 |
|
disease | 0.420 | None | 1.000 | 0 | 2 | 2007 | 2018 | ||||||||
|
tyrosinase | 0.473 | 0.808 | 5.0E-32 |
|
disease | 0.420 | None | 1.000 | 0 | 0 | 2008 | 2011 | ||||||||
|
ERCC excision repair 2, TFIIH core complex helicase subunit | 0.420 | 0.846 | 7.1E-20 |
|
disease | 0.170 | None | 0.857 | 0 | 0 | 1999 | 2014 | ||||||||
|
HRas proto-oncogene, GTPase | 0.378 | 0.885 | 8.0E-02 |
|
disease | 0.150 | None | 1.000 | 0 | 0 | 1989 | 2010 | ||||||||
|
Fas cell surface death receptor | 0.372 | 0.923 | 0.81 |
|
disease | 0.140 | None | 0.750 | 0 | 0 | 1998 | 2012 | ||||||||
|
transglutaminase 3 | 0.653 | 0.385 | 3.0E-06 |
|
disease | 0.120 | None | 1.000 | 1 | 2 | 2014 | 2019 | ||||||||
|
Fas ligand | 0.430 | 0.885 | 0.18 |
|
disease | 0.120 | None | 1.000 | 0 | 0 | 1998 | 2005 | ||||||||
|
OCA2 melanosomal transmembrane protein | 0.539 | 0.808 | 2.9E-13 |
|
disease | 0.120 | None | 1.000 | 0 | 0 | 2009 | 2011 | ||||||||
|
APC regulator of WNT signaling pathway | 0.373 | 0.962 | 1.00 |
|
disease | 0.120 | None | 1.000 | 0 | 0 | 2014 | 2015 | ||||||||
|
mutL homolog 1 | 0.399 | 0.808 | 3.4E-05 |
|
disease | 0.120 | None | 1.000 | 0 | 0 | 2005 | 2018 | ||||||||
|
XPC complex subunit, DNA damage recognition and repair factor | 0.504 | 0.808 | 3.7E-11 |
|
disease | 0.120 | None | 1.000 | 0 | 0 | 2014 | 2015 | ||||||||
|
mutS homolog 2 | 0.406 | 0.808 | 0.90 |
|
disease | 0.120 | None | 1.000 | 0 | 0 | 2005 | 2018 | ||||||||
|
CYLD lysine 63 deubiquitinase | 0.498 | 0.846 | 1.00 |
|
disease | 0.120 | None | 1.000 | 0 | 0 | 2011 | 2013 | ||||||||
|
transforming growth factor beta receptor 2 | 0.413 | 0.846 | 0.13 |
|
disease | 0.120 | None | 1.000 | 0 | 0 | 1996 | 1997 |