| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
sodium channel epithelial 1 subunit alpha | 0.601 | 0.577 | 1.1E-11 |
|
phenotype | 0.100 | None | 0 | 0 | |||||||||||
|
dynein axonemal heavy chain 1 | 0.656 | 0.615 | 1.5E-26 |
|
phenotype | 0.100 | None | 0 | 0 | |||||||||||
|
CF transmembrane conductance regulator | 0.424 | 0.885 | 2.2E-58 |
|
phenotype | 0.100 | None | 0 | 0 | |||||||||||
|
sodium channel epithelial 1 subunit beta | 0.628 | 0.577 | 5.8E-08 |
|
phenotype | 0.100 | None | 0 | 0 | |||||||||||
|
sodium channel epithelial 1 subunit gamma | 0.633 | 0.577 | 0.48 |
|
phenotype | 0.100 | None | 0 | 0 | |||||||||||
|
toll like receptor 6 | 0.556 | 0.769 | 2.3E-05 |
|
phenotype | 0.010 | None | < 0.001 | 1 | 0 | 2013 | 2013 | ||||||||
|
transient receptor potential cation channel subfamily V member 4 | 0.457 | 0.808 | 2.2E-16 |
|
phenotype | 0.010 | None | < 0.001 | 1 | 2 | 2010 | 2010 | ||||||||
|
secretoglobin family 1A member 1 | 0.546 | 0.808 | 8.0E-04 |
|
phenotype | 0.040 | None | 0.500 | 4 | 0 | 2007 | 2020 | ||||||||
|
methylenetetrahydrofolate reductase | 0.337 | 0.885 | 3.2E-10 |
|
phenotype | 0.020 | None | 0.500 | 2 | 1 | 2012 | 2013 | ||||||||
|
ADAM metallopeptidase domain 33 | 0.636 | 0.423 | 2.1E-15 |
|
phenotype | 0.020 | None | 0.500 | 2 | 3 | 2015 | 2016 | ||||||||
|
glutathione S-transferase mu 1 | 0.380 | 0.923 | 2.1E-03 |
|
phenotype | 0.070 | None | 0.714 | 7 | 0 | 2002 | 2013 | ||||||||
|
C-reactive protein | 0.299 | 0.962 | 3.7E-03 |
|
phenotype | 0.040 | None | 0.750 | 4 | 0 | 2009 | 2020 | ||||||||
|
interleukin 4 receptor | 0.474 | 0.846 | 2.3E-04 |
|
phenotype | 0.040 | None | 0.750 | 4 | 0 | 2004 | 2013 | ||||||||
|
C-X-C motif chemokine ligand 8 | 0.310 | 0.962 | 2.7E-04 |
|
phenotype | 0.060 | None | 0.833 | 6 | 0 | 2004 | 2019 | ||||||||
|
adrenoceptor beta 2 | 0.442 | 0.923 | 0.53 |
|
phenotype | 0.060 | None | 0.833 | 6 | 1 | 2004 | 2012 | ||||||||
|
interleukin 13 | 0.386 | 0.846 | 1.4E-02 |
|
phenotype | 0.070 | None | 0.857 | 7 | 3 | 2004 | 2019 | ||||||||
|
tumor necrosis factor | 0.231 | 0.962 | 0.80 |
|
phenotype | 0.090 | None | 0.889 | 9 | 2 | 2004 | 2019 | ||||||||
|
glutathione S-transferase pi 1 | 0.383 | 0.923 | 1.4E-02 |
|
phenotype | 0.400 | None | 0.909 | 11 | 3 | 2006 | 2017 | ||||||||
|
interleukin 10 | 0.281 | 0.923 | 5.9E-03 |
|
phenotype | 0.090 | None | 1.000 | 9 | 2 | 2007 | 2018 | ||||||||
|
hematopoietic prostaglandin D synthase | 0.388 | 0.923 | 1.8E-06 |
|
phenotype | 0.050 | None | 1.000 | 5 | 0 | 2002 | 2013 | ||||||||
|
interleukin 4 | 0.332 | 0.962 | 4.7E-03 |
|
phenotype | 0.350 | None | 1.000 | 5 | 1 | 2002 | 2017 | ||||||||
|
glutathione S-transferase kappa 1 | 0.412 | 0.885 | 1.9E-06 |
|
phenotype | 0.040 | None | 1.000 | 4 | 0 | 2002 | 2013 | ||||||||
|
ORMDL sphingolipid biosynthesis regulator 3 | 0.666 | 0.423 | 0.78 |
|
phenotype | 0.040 | None | 1.000 | 4 | 1 | 2011 | 2013 | ||||||||
|
Pulmonary disease, chronic obstructive, severe early-onset | 0.456 | 0.885 |
|
phenotype | 0.040 | None | 1.000 | 4 | 0 | 2017 | 2019 | |||||||||
|
C-C motif chemokine ligand 5 | 0.403 | 0.885 | 1.8E-03 |
|
phenotype | 0.040 | None | 1.000 | 4 | 0 | 2009 | 2019 |