Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 80332
Gene Symbol: ADAM33
ADAM33
CUI: C0043144
Disease: Wheezing
Wheezing 		0.020 GeneticVariation BEFREE Multiple associations were observed for ADAM33: rs2280090 was associated with reduced MEF240% (i.e., the ratio of Mean Expiratory Flow after 240s of hypertonic saline inhalation with respect to the age- and ancestry-matched reference value) and with an increased risk of allergic bronchitis (p = 1.77*10(-4) and p = 7.94*10(-4), respectively); rs3918396 was associated with wheezing and eczema comorbidity (p = 3.41*10(-4)). 27624002

2016
Entrez Id: 80332
Gene Symbol: ADAM33
ADAM33
CUI: C0043144
Disease: Wheezing
Wheezing 		0.020 GeneticVariation BEFREE When replicated in the KOALA study, ADAM33 rs528557 showed a negative association of the CG/GG-genotype with progression of recurrent wheeze into childhood asthma (0.50 (0.26-0.97) p = 0.04) and no association with preschool wheeze. 25768087

2015