| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Pulmonary disease, chronic obstructive, severe early-onset | 0.456 | 0.885 |
|
disease | 0.100 | None | 0.978 | 179 | 0 | 1996 | 2020 | |||||||||
|
serpin family A member 1 | 0.410 | 0.923 | 6.8E-08 |
|
disease | 0.500 | None | 0.990 | 101 | 30 | 1977 | 2020 | ||||||||
|
tumor necrosis factor | 0.231 | 0.962 | 0.80 |
|
disease | 0.400 | None | 0.952 | 84 | 3 | 2000 | 2020 | ||||||||
|
interleukin 6 | 0.248 | 0.962 | 0.32 |
|
disease | 0.400 | None | 0.967 | 60 | 1 | 2006 | 2020 | ||||||||
|
C-X-C motif chemokine ligand 8 | 0.310 | 0.962 | 2.7E-04 |
|
disease | 0.400 | None | 0.965 | 57 | 0 | 2000 | 2020 | ||||||||
|
matrix metallopeptidase 9 | 0.305 | 0.923 | 1.9E-17 |
|
disease | 0.600 | None | 0.979 | 48 | 4 | 2002 | 2019 | ||||||||
|
C-reactive protein | 0.299 | 0.962 | 3.7E-03 |
|
disease | 0.100 | None | 0.911 | 45 | 1 | 2006 | 2020 | ||||||||
|
FEV transcription factor, ETS family member | 0.593 | 0.692 | 8.1E-03 |
|
disease | 0.100 | None | 0.933 | 45 | 2 | 2000 | 2018 | ||||||||
|
transforming growth factor beta 1 | 0.287 | 0.962 | 3.7E-02 |
|
disease | 0.600 | None | 0.911 | 45 | 5 | 1994 | 2020 | ||||||||
|
adrenoceptor beta 2 | 0.442 | 0.923 | 0.53 |
|
disease | 0.100 | None | 1.000 | 36 | 5 | 1993 | 2019 | ||||||||
|
nuclear factor, erythroid 2 like 2 | 0.357 | 0.885 | 3.6E-03 |
|
disease | 0.300 | None | 0.972 | 36 | 2 | 2008 | 2019 | ||||||||
|
interleukin 1 beta | 0.276 | 0.962 | 0.13 |
|
disease | 0.100 | None | 0.941 | 34 | 1 | 2000 | 2020 | ||||||||
|
cholinergic receptor nicotinic alpha 3 subunit | 0.588 | 0.692 | 1.4E-07 |
|
disease | 0.200 | None | 0.970 | 33 | 19 | 2009 | 2019 | ||||||||
|
family with sequence similarity 13 member A | 0.653 | 0.462 | 1.9E-18 |
|
disease | 0.500 | None | 1.000 | 31 | 12 | 2010 | 2019 | ||||||||
|
angiotensin I converting enzyme | 0.328 | 0.923 | 1.0E-37 |
|
disease | 0.100 | None | 0.933 | 30 | 0 | 1999 | 2019 | ||||||||
|
matrix metallopeptidase 12 | 0.484 | 0.885 |
|
disease | 0.100 | None | 1.000 | 30 | 6 | 2002 | 2020 | |||||||||
|
elastin | 0.415 | 0.885 | 2.1E-14 |
|
disease | 0.400 | None | 1.000 | 28 | 1 | 2005 | 2019 | ||||||||
|
interleukin 17A | 0.324 | 0.923 | 4.3E-02 |
|
disease | 0.300 | None | 0.963 | 27 | 2 | 2004 | 2019 | ||||||||
|
phosphodiesterase 4A | 0.523 | 0.846 | 0.98 |
|
disease | 0.100 | None | 1.000 | 27 | 0 | 2004 | 2019 | ||||||||
|
vascular endothelial growth factor A | 0.266 | 0.923 | 2.4E-05 |
|
disease | 0.300 | None | 0.963 | 27 | 0 | 2003 | 2019 | ||||||||
|
epoxide hydrolase 1 | 0.500 | 0.846 | 3.2E-09 |
|
disease | 0.400 | None | 0.923 | 26 | 3 | 1997 | 2017 | ||||||||
|
interleukin 13 | 0.386 | 0.846 | 1.4E-02 |
|
disease | 0.100 | None | 0.962 | 26 | 4 | 2000 | 2020 | ||||||||
|
hedgehog interacting protein | 0.550 | 0.654 | 0.95 |
|
disease | 0.100 | None | 1.000 | 25 | 2 | 2009 | 2019 | ||||||||
|
surfactant protein D | 0.500 | 0.846 | 7.5E-05 |
|
disease | 0.700 | None | 0.917 | 24 | 8 | 2001 | 2019 | ||||||||
|
CF transmembrane conductance regulator | 0.424 | 0.885 | 2.2E-58 |
|
disease | 0.200 | None | 1.000 | 23 | 4 | 2001 | 2019 |