| Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
|---|---|---|---|---|---|---|---|---|---|---|
|
0.030 | GeneticVariation | BEFREE | For rs20541, the results suggested an association between rs20541 and COPD risk in Caucasians under the recessive model (OR = 2.79, 95% CI: 1.13-6.92, Pz = .026), whereas this SNP was not associated with COPD in Asians.This meta-analysis suggests that the T allele of rs1800925 is associated with the increased risk of COPD in both Asians and Caucasians, whereas rs20541 is associated with the risk of COPD in Caucasians but not in Asians. | 29381928 | 2017 |
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|
0.030 | GeneticVariation | BEFREE | Association was found between IL-13 gene SNPs (rs20541 and rs1800925) and an increased risk of COPD. | 24286397 | 2013 |
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|
0.030 | GeneticVariation | BEFREE | IL13 SNPs rs2066960(intron 1), rs20541(R130Q) and rs1295685(exon 4) were associated with COPD risk and lower baseline lung function in the recessive model. | 19796199 | 2010 |
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|
0.020 | GeneticVariation | BEFREE | In subgroup analysis according to ethnicity, the T allele of rs1800925 was associated with an increased risk of COPD in Asians (OR = 1.88, 95% CI: 1.23-2.87, Pz = .004) and Caucasians (OR = 1.30, 95% CI: 1.01-1.67, Pz = .041), respectively. | 29381928 | 2017 |
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|
0.020 | GeneticVariation | BEFREE | Association was found between IL-13 gene SNPs (rs20541 and rs1800925) and an increased risk of COPD. | 24286397 | 2013 |
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|
0.010 | GeneticVariation | BEFREE | IL13 SNPs rs2066960(intron 1), rs20541(R130Q) and rs1295685(exon 4) were associated with COPD risk and lower baseline lung function in the recessive model. | 19796199 | 2010 |
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|
0.010 | GeneticVariation | BEFREE | IL13 SNPs rs2066960(intron 1), rs20541(R130Q) and rs1295685(exon 4) were associated with COPD risk and lower baseline lung function in the recessive model. | 19796199 | 2010 |