Source: PSYGENET

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 361
Gene Symbol: AQP4
AQP4
CUI: C0338715
Disease: Drug-induced depressive state
Drug-induced depressive state 		0.300 Biomarker PSYGENET Aquaporin-4 knockout exacerbates corticosterone-induced depression by inhibiting astrocyte function and hippocampal neurogenesis. 24422972

2014
Entrez Id: 627
Gene Symbol: BDNF
BDNF
CUI: C0338715
Disease: Drug-induced depressive state
Drug-induced depressive state 		0.300 Biomarker PSYGENET Chronic fluoxetine treatment induces brain region-specific upregulation of genes associated with BDNF-induced long-term potentiation. 18301726

2007
Entrez Id: 1432
Gene Symbol: MAPK14
MAPK14
CUI: C0338715
Disease: Drug-induced depressive state
Drug-induced depressive state 		0.300 Biomarker PSYGENET Early activation of p38 mitogen activated protein kinase is associated with interferon-alpha-induced depression and fatigue. 21356304

2011
Entrez Id: 51083
Gene Symbol: GAL
GAL
CUI: C0338715
Disease: Drug-induced depressive state
Drug-induced depressive state 		0.300 Biomarker PSYGENET Fluoxetine reverts chronic restraint stress-induced depression-like behaviour and increases neuropeptide Y and galanin expression in mice. 20816900

2011
Entrez Id: 627
Gene Symbol: BDNF
BDNF
CUI: C0338715
Disease: Drug-induced depressive state
Drug-induced depressive state 		0.300 Biomarker PSYGENET Gender-specific impact of brain-derived neurotrophic factor signaling on stress-induced depression-like behavior. 19358977

2009
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
CUI: C0338715
Disease: Drug-induced depressive state
Drug-induced depressive state 		0.300 Biomarker PSYGENET Interferon-gamma (+874) T/A genotypes and risk of IFN-alpha-induced depression. 21161299

2011
Entrez Id: 4939
Gene Symbol: OAS2
OAS2
CUI: C0338715
Disease: Drug-induced depressive state
Drug-induced depressive state 		0.300 Biomarker PSYGENET Molecular signatures of peripheral blood mononuclear cells during chronic interferon-α treatment: relationship with depression and fatigue. 22152193

2012
Entrez Id: 5319
Gene Symbol: PLA2G1B
PLA2G1B
CUI: C0338715
Disease: Drug-induced depressive state
Drug-induced depressive state 		0.300 Biomarker PSYGENET Phospholipase A2 and cyclooxygenase 2 genes influence the risk of interferon-alpha-induced depression by regulating polyunsaturated fatty acids levels. 20034614

2010
Entrez Id: 3454
Gene Symbol: IFNAR1
IFNAR1
CUI: C0338715
Disease: Drug-induced depressive state
Drug-induced depressive state 		0.300 Biomarker PSYGENET Promoter polymorphisms of the interferon-alpha receptor gene and development of Interferon-induced depressive symptoms in patients with chronic hepatitis C: preliminary findings. 15990456

2005
Entrez Id: 361
Gene Symbol: AQP4
AQP4
CUI: C0338715
Disease: Drug-induced depressive state
Drug-induced depressive state 		0.300 Biomarker PSYGENET Requirement of AQP4 for antidepressive efficiency of fluoxetine: implication in adult hippocampal neurogenesis. 18923397

2009
Entrez Id: 875
Gene Symbol: CBS
CBS
CUI: C0338715
Disease: Drug-induced depressive state
Drug-induced depressive state 		0.300 Biomarker PSYGENET Selective detection of endogenous H₂S in living cells and the mouse hippocampus using a ratiometric fluorescent probe. 25070356

2014
Entrez Id: 3569
Gene Symbol: IL6
IL6
CUI: C0338715
Disease: Drug-induced depressive state
Drug-induced depressive state 		0.300 Biomarker PSYGENET Serotonin and interleukin-6: the role of genetic polymorphisms in IFN-induced neuropsychiatric symptoms. 23571152

2013
Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
CUI: C0338715
Disease: Drug-induced depressive state
Drug-induced depressive state 		0.300 Biomarker PSYGENET Serotonin transporter mRNA expression is decreased by lamivudine and ribavirin and increased by interferon in immune cells. 16476009

2006
Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
CUI: C0338715
Disease: Drug-induced depressive state
Drug-induced depressive state 		0.300 Biomarker PSYGENET Serotonin-1A receptor gene HTR1A variation predicts interferon-induced depression in chronic hepatitis C. 17408646

2007
Entrez Id: 3060
Gene Symbol: HCRT
HCRT
CUI: C0338715
Disease: Drug-induced depressive state
Drug-induced depressive state 		0.300 Biomarker PSYGENET The effect of clomipramine on wake/sleep and orexinergic expression in rats. 18562438

2009
Entrez Id: 627
Gene Symbol: BDNF
BDNF
CUI: C0338715
Disease: Drug-induced depressive state
Drug-induced depressive state 		0.300 Biomarker PSYGENET Upregulated mRNA levels of SERT, NET, MAOB, and BDNF in various brain regions of ovariectomized rats exposed to chronic aversive stimuli. 23208077

2013