Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4322
Gene Symbol: MMP13
MMP13
matrix metallopeptidase 13 0.452 0.923 7.9E-18
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.200 None 0.983 172 0 1996 2020
Entrez Id: 176
Gene Symbol: ACAN
ACAN
aggrecan 0.528 0.846 1.00
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.200 None 1.000 105 0 1996 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
vascular endothelial growth factor A 0.266 0.923 2.4E-05
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.100 None 0.977 44 0 1997 2020
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
catenin beta 1 0.303 0.885 1.00
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.100 None 0.976 42 0 2009 2020
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta 0.319 0.885 1.00
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.100 None 1.000 36 0 2012 2020
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha 0.292 0.923 1.00
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.100 None 1.000 35 0 2012 2020
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta 0.322 0.885 1.00
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.100 None 1.000 35 0 2012 2020
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma 0.320 0.885 1.4E-06
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.100 None 1.000 35 0 2012 2020
Entrez Id: 4513
Gene Symbol: COX2
COX2
cytochrome c oxidase subunit II 0.352 0.962
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.100 None 1.000 34 0 1998 2020
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
mitogen-activated protein kinase 1 0.330 0.923 1.00
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.100 None 0.968 31 0 2007 2020
Entrez Id: 3952
Gene Symbol: LEP
LEP
leptin 0.349 0.846 0.46
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.100 None 0.968 30 0 2003 2019
Entrez Id: 107075310
Gene Symbol: MTCO2P12
MTCO2P12
MT-CO2 pseudogene 12 0.368 0.962
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.100 None 1.000 29 0 1998 2020
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
insulin like growth factor 1 0.318 0.885 0.27
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.100 None 0.929 28 0 1995 2020
Entrez Id: 860
Gene Symbol: RUNX2
RUNX2
RUNX family transcription factor 2 0.437 0.846 0.95
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.400 None 1.000 27 0 2008 2020
Entrez Id: 4803
Gene Symbol: NGF
NGF
nerve growth factor 0.391 0.885 0.82
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.100 None 1.000 26 0 2002 2020
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
sirtuin 1 0.378 0.885 8.7E-02
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.100 None 1.000 25 0 2010 2019
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
matrix metallopeptidase 9 0.305 0.923 1.9E-17
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.100 None 1.000 25 0 1997 2019
Entrez Id: 406932
Gene Symbol: MIR140
MIR140
microRNA 140 0.522 0.769
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.100 None 1.000 24 0 2009 2020
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
nuclear factor, erythroid 2 like 2 0.357 0.885 3.6E-03
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.100 None 1.000 23 0 2017 2019
Entrez Id: 10216
Gene Symbol: PRG4
PRG4
proteoglycan 4 0.601 0.615 1.7E-08
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.100 None 0.955 22 0 2013 2019
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
secreted phosphoprotein 1 0.353 0.885 2.1E-06
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.100 None 0.955 22 0 2000 2020
Entrez Id: 6387
Gene Symbol: CXCL12
CXCL12
C-X-C motif chemokine ligand 12 0.379 0.846 0.12
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.100 None 0.955 21 0 2002 2019
Entrez Id: 2551
Gene Symbol: GABPA
GABPA
GA binding protein transcription factor subunit alpha 0.379 0.885 1.00
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.100 None 1.000 20 0 2017 2019
Entrez Id: 7076
Gene Symbol: TIMP1
TIMP1
TIMP metallopeptidase inhibitor 1 0.380 0.885 0.50
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.100 None 1.000 20 0 1993 2020
Entrez Id: 1432
Gene Symbol: MAPK14
MAPK14
mitogen-activated protein kinase 14 0.379 0.923 0.37
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.100 None 1.000 19 0 2007 2020