| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
interleukin 1 beta | 0.276 | 0.962 | 0.13 |
|
disease | 0.400 | None | 0.997 | 377 | 4 | 1992 | 2020 | ||||||||
|
matrix metallopeptidase 13 | 0.452 | 0.923 | 7.9E-18 |
|
disease | 0.200 | None | 0.983 | 172 | 0 | 1996 | 2020 | ||||||||
|
tumor necrosis factor | 0.231 | 0.962 | 0.80 |
|
disease | 0.100 | None | 0.989 | 171 | 2 | 1989 | 2020 | ||||||||
|
interleukin 6 | 0.248 | 0.962 | 0.32 |
|
disease | 0.100 | None | 1.000 | 111 | 3 | 1990 | 2020 | ||||||||
|
aggrecan | 0.528 | 0.846 | 1.00 |
|
disease | 0.200 | None | 1.000 | 105 | 0 | 1996 | 2019 | ||||||||
|
prostaglandin-endoperoxide synthase 2 | 0.314 | 0.962 | 1.00 |
|
disease | 0.100 | None | 1.000 | 65 | 1 | 1997 | 2020 | ||||||||
|
collagen type II alpha 1 chain | 0.444 | 0.846 | 1.00 |
|
disease | 0.500 | None | 0.941 | 63 | 4 | 1993 | 2020 | ||||||||
|
interleukin 1 alpha | 0.333 | 0.962 | 1.6E-04 |
|
disease | 0.100 | None | 0.967 | 60 | 2 | 1992 | 2020 | ||||||||
|
matrix metallopeptidase 3 | 0.408 | 0.885 | 5.7E-15 |
|
disease | 0.100 | None | 0.981 | 53 | 5 | 1996 | 2019 | ||||||||
|
ADAM metallopeptidase with thrombospondin type 1 motif 5 | 0.597 | 0.654 | 8.0E-07 |
|
disease | 0.100 | None | 0.962 | 51 | 2 | 2002 | 2020 | ||||||||
|
transforming growth factor beta 1 | 0.287 | 0.962 | 3.7E-02 |
|
disease | 0.500 | None | 1.000 | 49 | 2 | 2000 | 2020 | ||||||||
|
growth differentiation factor 5 | 0.511 | 0.692 | 0.67 |
|
disease | 0.400 | None | 0.960 | 47 | 2 | 2007 | 2019 | ||||||||
|
vascular endothelial growth factor A | 0.266 | 0.923 | 2.4E-05 |
|
disease | 0.100 | None | 0.977 | 44 | 0 | 1997 | 2020 | ||||||||
|
catenin beta 1 | 0.303 | 0.885 | 1.00 |
|
disease | 0.100 | None | 0.976 | 42 | 0 | 2009 | 2020 | ||||||||
|
matrix metallopeptidase 1 | 0.385 | 0.885 | 7.7E-18 |
|
disease | 0.100 | None | 0.975 | 39 | 2 | 1996 | 2019 | ||||||||
|
interleukin 1 receptor antagonist | 0.373 | 0.923 | 3.1E-02 |
|
disease | 0.100 | None | 0.973 | 36 | 1 | 1992 | 2019 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta | 0.319 | 0.885 | 1.00 |
|
disease | 0.100 | None | 1.000 | 36 | 0 | 2012 | 2020 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 0.292 | 0.923 | 1.00 |
|
disease | 0.100 | None | 1.000 | 35 | 0 | 2012 | 2020 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta | 0.322 | 0.885 | 1.00 |
|
disease | 0.100 | None | 1.000 | 35 | 0 | 2012 | 2020 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma | 0.320 | 0.885 | 1.4E-06 |
|
disease | 0.100 | None | 1.000 | 35 | 0 | 2012 | 2020 | ||||||||
|
C-X-C motif chemokine ligand 8 | 0.310 | 0.962 | 2.7E-04 |
|
disease | 0.100 | None | 0.971 | 34 | 2 | 1994 | 2019 | ||||||||
|
cytochrome c oxidase subunit II | 0.352 | 0.962 |
|
disease | 0.100 | None | 1.000 | 34 | 0 | 1998 | 2020 | |||||||||
|
cartilage oligomeric matrix protein | 0.503 | 0.808 | 1.3E-09 |
|
disease | 0.500 | None | 0.971 | 33 | 3 | 1995 | 2019 | ||||||||
|
ADAM metallopeptidase with thrombospondin type 1 motif 4 | 0.582 | 0.692 | 2.0E-06 |
|
disease | 0.100 | None | 0.971 | 33 | 2 | 2002 | 2020 | ||||||||
|
SMAD family member 3 | 0.415 | 0.923 | 0.80 |
|
disease | 0.400 | None | 0.969 | 31 | 8 | 2003 | 2019 |