| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
renin | 0.370 | 0.923 | 2.4E-07 |
|
group | 0.100 | None | 0.973 | 149 | 0 | 1994 | 2020 | ||||||||
|
solute carrier family 5 member 2 | 0.499 | 0.769 | 4.9E-14 |
|
group | 0.100 | None | 0.942 | 52 | 0 | 2017 | 2020 | ||||||||
|
fibroblast growth factor 23 | 0.460 | 0.731 | 3.1E-02 |
|
group | 0.100 | None | 0.958 | 48 | 0 | 2013 | 2020 | ||||||||
|
dipeptidyl peptidase 4 | 0.420 | 0.808 | 7.3E-09 |
|
group | 0.100 | None | 0.976 | 41 | 0 | 2009 | 2019 | ||||||||
|
sex hormone binding globulin | 0.438 | 0.808 | 1.3E-06 |
|
group | 0.100 | None | 0.949 | 39 | 0 | 2006 | 2020 | ||||||||
|
Pulmonary disease, chronic obstructive, severe early-onset | 0.456 | 0.885 |
|
group | 0.100 | None | 0.970 | 33 | 0 | 2009 | 2020 | |||||||||
|
insulin like growth factor 1 | 0.318 | 0.885 | 0.27 |
|
group | 0.100 | None | 1.000 | 30 | 0 | 1999 | 2020 | ||||||||
|
euchromatic histone lysine methyltransferase 1 | 0.460 | 0.808 | 1.00 |
|
group | 0.100 | None | 0.931 | 29 | 0 | 2013 | 2020 | ||||||||
|
glucagon | 0.431 | 0.885 | 3.5E-02 |
|
group | 0.100 | None | 0.929 | 28 | 0 | 2013 | 2019 | ||||||||
|
glucagon like peptide 1 receptor | 0.471 | 0.846 | 0.29 |
|
group | 0.100 | None | 0.893 | 28 | 0 | 2013 | 2019 | ||||||||
|
haptoglobin | 0.412 | 0.885 | 1.7E-05 |
|
group | 0.400 | None | 0.963 | 27 | 0 | 1997 | 2019 | ||||||||
|
nuclear receptor subfamily 3 group C member 2 | 0.469 | 0.846 | 0.84 |
|
group | 0.100 | None | 1.000 | 26 | 0 | 2008 | 2020 | ||||||||
|
TNF receptor superfamily member 11b | 0.422 | 0.808 | 0.16 |
|
group | 0.100 | None | 1.000 | 26 | 0 | 2004 | 2019 | ||||||||
|
coiled-coil alpha-helical rod protein 1 | 0.505 | 0.808 | 1.0E-16 |
|
group | 0.100 | None | 1.000 | 25 | 0 | 2017 | 2020 | ||||||||
|
selenium binding protein 1 | 0.493 | 0.846 | 3.2E-16 |
|
group | 0.100 | None | 1.000 | 25 | 0 | 2017 | 2020 | ||||||||
|
interleukin 1 beta | 0.276 | 0.962 | 0.13 |
|
group | 0.100 | None | 1.000 | 24 | 0 | 1998 | 2020 | ||||||||
|
klotho | 0.448 | 0.769 | 2.2E-04 |
|
group | 0.100 | None | 1.000 | 24 | 0 | 2006 | 2020 | ||||||||
|
parathyroid hormone | 0.397 | 0.846 | 1.2E-02 |
|
group | 0.100 | None | 1.000 | 22 | 0 | 2011 | 2019 | ||||||||
|
nuclear factor, erythroid 2 like 2 | 0.357 | 0.885 | 3.6E-03 |
|
group | 0.100 | None | 1.000 | 21 | 0 | 2009 | 2020 | ||||||||
|
C-C motif chemokine ligand 2 | 0.321 | 0.962 | 0.61 |
|
group | 0.400 | None | 0.952 | 21 | 0 | 2003 | 2020 | ||||||||
|
apelin | 0.497 | 0.769 | 0.46 |
|
group | 0.100 | None | 1.000 | 21 | 0 | 2009 | 2019 | ||||||||
|
heme oxygenase 1 | 0.381 | 0.923 | 9.7E-03 |
|
group | 0.100 | None | 0.833 | 18 | 0 | 2005 | 2020 | ||||||||
|
adrenomedullin | 0.436 | 0.808 | 4.1E-02 |
|
group | 0.100 | None | 1.000 | 17 | 0 | 1999 | 2019 | ||||||||
|
galectin 3 | 0.392 | 0.846 | 2.3E-05 |
|
group | 0.100 | None | 0.941 | 17 | 0 | 2013 | 2020 | ||||||||
|
matrix metallopeptidase 2 | 0.333 | 0.923 | 0.84 |
|
group | 0.100 | None | 0.882 | 17 | 0 | 2007 | 2020 |