Source: CTD_human

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
CUI: C0270192
Disease: Perinatal Subarachnoid Hemorrhage
Perinatal Subarachnoid Hemorrhage
0.300 Biomarker CTD_human Recombinant Netrin-1 binding UNC5B receptor attenuates neuroinflammation and brain injury via PPARγ/NFκB signaling pathway after subarachnoid hemorrhage in rats. 29162556

2018

Entrez Id: 5468
Gene Symbol: PPARG
PPARG
CUI: C0276496
Disease: Familial Alzheimer Disease (FAD)
Familial Alzheimer Disease (FAD)
0.300 Biomarker CTD_human Inhibition of miR-128 Abates Aβ-Mediated Cytotoxicity by Targeting PPAR-γ via NF-κB Inactivation in Primary Mouse Cortical Neurons and Neuro2a Cells. 30328325

2018

Entrez Id: 5468
Gene Symbol: PPARG
PPARG
Subarachnoid Hemorrhage, Spontaneous
0.300 Biomarker CTD_human Recombinant Netrin-1 binding UNC5B receptor attenuates neuroinflammation and brain injury via PPARγ/NFκB signaling pathway after subarachnoid hemorrhage in rats. 29162556

2018

Entrez Id: 5468
Gene Symbol: PPARG
PPARG
CUI: C0546126
Disease: Acute Confusional Senile Dementia
Acute Confusional Senile Dementia
0.300 Biomarker CTD_human Inhibition of miR-128 Abates Aβ-Mediated Cytotoxicity by Targeting PPAR-γ via NF-κB Inactivation in Primary Mouse Cortical Neurons and Neuro2a Cells. 30328325

2018

Entrez Id: 5468
Gene Symbol: PPARG
PPARG
CUI: C0750900
Disease: Alzheimer's Disease, Focal Onset
Alzheimer's Disease, Focal Onset
0.300 Biomarker CTD_human Inhibition of miR-128 Abates Aβ-Mediated Cytotoxicity by Targeting PPAR-γ via NF-κB Inactivation in Primary Mouse Cortical Neurons and Neuro2a Cells. 30328325

2018

Entrez Id: 5468
Gene Symbol: PPARG
PPARG
CUI: C0750901
Disease: Alzheimer Disease, Early Onset
Alzheimer Disease, Early Onset
0.300 Biomarker CTD_human Inhibition of miR-128 Abates Aβ-Mediated Cytotoxicity by Targeting PPAR-γ via NF-κB Inactivation in Primary Mouse Cortical Neurons and Neuro2a Cells. 30328325

2018

Entrez Id: 5468
Gene Symbol: PPARG
PPARG
CUI: C0751530
Disease: Subarachnoid Hemorrhage, Aneurysmal
Subarachnoid Hemorrhage, Aneurysmal
0.300 Biomarker CTD_human Recombinant Netrin-1 binding UNC5B receptor attenuates neuroinflammation and brain injury via PPARγ/NFκB signaling pathway after subarachnoid hemorrhage in rats. 29162556

2018

Entrez Id: 5468
Gene Symbol: PPARG
PPARG
Subarachnoid Hemorrhage, Intracranial
0.300 Biomarker CTD_human Recombinant Netrin-1 binding UNC5B receptor attenuates neuroinflammation and brain injury via PPARγ/NFκB signaling pathway after subarachnoid hemorrhage in rats. 29162556

2018

Entrez Id: 5468
Gene Symbol: PPARG
PPARG
CUI: C0017667
Disease: Nodular glomerulosclerosis
Nodular glomerulosclerosis
0.300 Biomarker CTD_human Nephropathy in Pparg-null mice highlights PPARγ systemic activities in metabolism and in the immune system. 28182703

2017

Entrez Id: 5468
Gene Symbol: PPARG
PPARG
CUI: C0085278
Disease: Antiphospholipid Syndrome
Antiphospholipid Syndrome
0.300 Biomarker CTD_human Nephropathy in Pparg-null mice highlights PPARγ systemic activities in metabolism and in the immune system. 28182703

2017

Entrez Id: 5468
Gene Symbol: PPARG
PPARG
CUI: C0023212
Disease: Left-Sided Heart Failure
Left-Sided Heart Failure
0.300 Biomarker CTD_human Inhibition of G-protein-coupled Receptor Kinase 2 Prevents the Dysfunctional Cardiac Substrate Metabolism in Fatty Acid Synthase Transgenic Mice. 26670611

2016

Entrez Id: 5468
Gene Symbol: PPARG
PPARG
CUI: C1959583
Disease: Myocardial Failure
Myocardial Failure
0.300 Biomarker CTD_human Inhibition of G-protein-coupled Receptor Kinase 2 Prevents the Dysfunctional Cardiac Substrate Metabolism in Fatty Acid Synthase Transgenic Mice. 26670611

2016

Entrez Id: 5468
Gene Symbol: PPARG
PPARG
CUI: C1961112
Disease: Heart Decompensation
Heart Decompensation
0.300 Biomarker CTD_human Inhibition of G-protein-coupled Receptor Kinase 2 Prevents the Dysfunctional Cardiac Substrate Metabolism in Fatty Acid Synthase Transgenic Mice. 26670611

2016

Entrez Id: 5468
Gene Symbol: PPARG
PPARG
CUI: C1565662
Disease: Acute Kidney Insufficiency
Acute Kidney Insufficiency
0.300 Therapeutic CTD_human Explicit role of peroxisome proliferator-activated receptor gamma in gallic acid-mediated protection against ischemia-reperfusion-induced acute kidney injury in rats. 24433871

2014

Entrez Id: 5468
Gene Symbol: PPARG
PPARG
CUI: C1565662
Disease: Acute Kidney Insufficiency
Acute Kidney Insufficiency
0.300 Biomarker CTD_human Explicit role of peroxisome proliferator-activated receptor gamma in gallic acid-mediated protection against ischemia-reperfusion-induced acute kidney injury in rats. 24433871

2014

Entrez Id: 5468
Gene Symbol: PPARG
PPARG
CUI: C1565662
Disease: Acute Kidney Insufficiency
Acute Kidney Insufficiency
0.300 Biomarker CTD_human Involvement of peroxisome proliferator-activated receptor gamma in vitamin D-mediated protection against acute kidney injury in rats. 24011919

2013

Entrez Id: 5468
Gene Symbol: PPARG
PPARG
CUI: C1565662
Disease: Acute Kidney Insufficiency
Acute Kidney Insufficiency
0.300 Therapeutic CTD_human Involvement of peroxisome proliferator-activated receptor gamma in vitamin D-mediated protection against acute kidney injury in rats. 24011919

2013

Entrez Id: 5468
Gene Symbol: PPARG
PPARG
CUI: C0236811
Disease: Chronobiology Disorders
Chronobiology Disorders
0.300 Biomarker CTD_human Systemic PPARγ deletion impairs circadian rhythms of behavior and metabolism. 22899986

2012

Entrez Id: 5468
Gene Symbol: PPARG
PPARG
CUI: C0813142
Disease: Circadian Rhythm Disorders
Circadian Rhythm Disorders
0.300 Biomarker CTD_human Systemic PPARγ deletion impairs circadian rhythms of behavior and metabolism. 22899986

2012

Entrez Id: 5468
Gene Symbol: PPARG
PPARG
Psychogenic Inversion of Circadian Rhythm
0.300 Biomarker CTD_human Systemic PPARγ deletion impairs circadian rhythms of behavior and metabolism. 22899986

2012

Entrez Id: 5468
Gene Symbol: PPARG
PPARG
CUI: C0002152
Disease: Alloxan Diabetes
Alloxan Diabetes
0.300 Biomarker CTD_human PPARγ activation induces acute PAI-1 gene expression in the liver but not in adipose tissues of diabetic model mice. 21757225

2011

Entrez Id: 5468
Gene Symbol: PPARG
PPARG
CUI: C0023794
Disease: Lipoidosis
Lipoidosis
0.300 Biomarker CTD_human Phospholipidosis induced by PPARγ signaling in human bronchial epithelial (BEAS-2B) cells exposed to amiodarone. 21123845

2011

Entrez Id: 5468
Gene Symbol: PPARG
PPARG
CUI: C0038433
Disease: Streptozotocin Diabetes
Streptozotocin Diabetes
0.300 Biomarker CTD_human PPARγ activation induces acute PAI-1 gene expression in the liver but not in adipose tissues of diabetic model mice. 21757225

2011

Entrez Id: 5468
Gene Symbol: PPARG
PPARG
CUI: C0156147
Disease: Crohn's disease of large bowel
Crohn's disease of large bowel
0.300 Biomarker CTD_human Probiotics modulate intestinal expression of nuclear receptor and provide counter-regulatory signals to inflammation-driven adipose tissue activation. 21829567

2011

Entrez Id: 5468
Gene Symbol: PPARG
PPARG
CUI: C0267380
Disease: Crohn's disease of the ileum
Crohn's disease of the ileum
0.300 Biomarker CTD_human Probiotics modulate intestinal expression of nuclear receptor and provide counter-regulatory signals to inflammation-driven adipose tissue activation. 21829567

2011