Source: CTD_human

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
CUI: C0678202
Disease: Regional enteritis
Regional enteritis 		0.300 Biomarker CTD_human Probiotics modulate intestinal expression of nuclear receptor and provide counter-regulatory signals to inflammation-driven adipose tissue activation. 21829567

2011
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
CUI: C0920563
Disease: Insulin Sensitivity
Insulin Sensitivity 		0.300 Therapeutic CTD_human Stable reporter cell lines for peroxisome proliferator-activated receptor γ (PPARγ)-mediated modulation of gene expression. 21354099

2011
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
CUI: C0920563
Disease: Insulin Sensitivity
Insulin Sensitivity 		0.300 Therapeutic CTD_human Dual acting and pan-PPAR activators as potential anti-diabetic therapies. 21484566

2011
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
CUI: C0949272
Disease: IIeocolitis
IIeocolitis 		0.300 Biomarker CTD_human Probiotics modulate intestinal expression of nuclear receptor and provide counter-regulatory signals to inflammation-driven adipose tissue activation. 21829567

2011
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
CUI: C1565662
Disease: Acute Kidney Insufficiency
Acute Kidney Insufficiency 		0.300 Biomarker CTD_human Phenotypic and genotypic assessment of concomitant drug-induced toxic effects in liver, kidney and blood. 20623750

2011
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
CUI: C1565662
Disease: Acute Kidney Insufficiency
Acute Kidney Insufficiency 		0.300 Therapeutic CTD_human Phenotypic and genotypic assessment of concomitant drug-induced toxic effects in liver, kidney and blood. 20623750

2011
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
CUI: C0887850
Disease: Polycystic Kidney, Type 1 Autosomal Dominant Disease
Polycystic Kidney, Type 1 Autosomal Dominant Disease 		0.300 Biomarker CTD_human Rosiglitazone inhibits cell proliferation by inducing G1 cell cycle arrest and apoptosis in ADPKD cyst-lining epithelia cells. 20210794

2010
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
CUI: C2751306
Disease: Polycystic kidney disease, type 2
Polycystic kidney disease, type 2 		0.300 Biomarker CTD_human Rosiglitazone inhibits cell proliferation by inducing G1 cell cycle arrest and apoptosis in ADPKD cyst-lining epithelia cells. 20210794

2010
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer 		0.300 Therapeutic CTD_human Effects of ciglitazone and troglitazone on the proliferation of human stomach cancer cells. 19140230

2009
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer 		0.300 Biomarker CTD_human Effects of ciglitazone and troglitazone on the proliferation of human stomach cancer cells. 19140230

2009
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
CUI: C0027746
Disease: Nerve Degeneration
Nerve Degeneration 		0.300 Therapeutic CTD_human Activation of cerebral peroxisome proliferator-activated receptors gamma exerts neuroprotection by inhibiting oxidative stress following pilocarpine-induced status epilepticus. 18289512

2008
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
CUI: C0079772
Disease: T-Cell Lymphoma
T-Cell Lymphoma 		0.300 Biomarker CTD_human In this report, we show that PPARgamma is expressed in human primary T-cell lymphoma tissues and activation of PPARgamma with low doses of ligands protects lymphoma cells from serum starvation-induced apoptosis. 17255338

2007
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
CUI: C0086743
Disease: Osteoarthrosis Deformans
Osteoarthrosis Deformans 		0.300 Biomarker CTD_human Distinctive gene expression signatures in rheumatoid arthritis synovial tissue fibroblast cells: correlates with disease activity. 17568789

2007
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
CUI: C1563937
Disease: Atherogenesis
Atherogenesis 		0.300 Therapeutic CTD_human [Rosiglitazone enhances the anti-atherosclerotic effects of peroxisome proliferator-activated receptor gamma1 gene transfer in apolipoprotein-knock out mice]. 18269830

2007
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
CUI: C0276496
Disease: Familial Alzheimer Disease (FAD)
Familial Alzheimer Disease (FAD) 		0.300 Biomarker CTD_human Nonsteroidal anti-inflammatory drugs repress beta-secretase gene promoter activity by the activation of PPARgamma. 16407166

2006
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
CUI: C0546126
Disease: Acute Confusional Senile Dementia
Acute Confusional Senile Dementia 		0.300 Biomarker CTD_human Nonsteroidal anti-inflammatory drugs repress beta-secretase gene promoter activity by the activation of PPARgamma. 16407166

2006
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
CUI: C0750900
Disease: Alzheimer's Disease, Focal Onset
Alzheimer's Disease, Focal Onset 		0.300 Biomarker CTD_human Nonsteroidal anti-inflammatory drugs repress beta-secretase gene promoter activity by the activation of PPARgamma. 16407166

2006
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
CUI: C0750901
Disease: Alzheimer Disease, Early Onset
Alzheimer Disease, Early Onset 		0.300 Biomarker CTD_human Nonsteroidal anti-inflammatory drugs repress beta-secretase gene promoter activity by the activation of PPARgamma. 16407166

2006
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
CUI: C0751220
Disease: Inappropriate ACTH Secretion Syndrome
Inappropriate ACTH Secretion Syndrome 		0.300 Therapeutic CTD_human New aspects in the diagnosis and treatment of Cushing disease. 16809932

2006
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
CUI: C0002152
Disease: Alloxan Diabetes
Alloxan Diabetes 		0.300 Biomarker CTD_human Chronic hyperglycemia, independent of plasma lipid levels, is sufficient for the loss of beta-cell differentiation and secretory function in the db/db mouse model of diabetes. 16123366

2005
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
CUI: C0038433
Disease: Streptozotocin Diabetes
Streptozotocin Diabetes 		0.300 Biomarker CTD_human Chronic hyperglycemia, independent of plasma lipid levels, is sufficient for the loss of beta-cell differentiation and secretory function in the db/db mouse model of diabetes. 16123366

2005
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
CUI: C0276496
Disease: Familial Alzheimer Disease (FAD)
Familial Alzheimer Disease (FAD) 		0.300 Biomarker CTD_human Agonists of peroxisome proliferator-activated receptor-gamma attenuate the Abeta-mediated impairment of LTP in the hippocampus in vitro. 15993441

2005
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
CUI: C0546126
Disease: Acute Confusional Senile Dementia
Acute Confusional Senile Dementia 		0.300 Biomarker CTD_human Agonists of peroxisome proliferator-activated receptor-gamma attenuate the Abeta-mediated impairment of LTP in the hippocampus in vitro. 15993441

2005
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
CUI: C0598784
Disease: Dyslipoproteinemias
Dyslipoproteinemias 		0.300 Therapeutic CTD_human Dual and pan-peroxisome proliferator-activated receptors (PPAR) co-agonism: the bezafibrate lessons. 16168052

2005
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
CUI: C0750900
Disease: Alzheimer's Disease, Focal Onset
Alzheimer's Disease, Focal Onset 		0.300 Biomarker CTD_human Agonists of peroxisome proliferator-activated receptor-gamma attenuate the Abeta-mediated impairment of LTP in the hippocampus in vitro. 15993441

2005