Source: BEFREE

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5443
Gene Symbol: POMC
POMC
proopiomelanocortin 0.356 0.846 1.2E-04
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
group 0.400 None 0.989 23 0 1974 2020
Entrez Id: 5972
Gene Symbol: REN
REN
renin 0.370 0.923 2.4E-07
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
group 0.600 None 0.969 653 3 1975 2020
Entrez Id: 1621
Gene Symbol: DBH
DBH
dopamine beta-hydroxylase 0.511 0.846 3.3E-10
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
group 0.250 None 0.833 5 0 1975 2019
Entrez Id: 4015
Gene Symbol: LOX
LOX
lysyl oxidase 0.447 0.846 0.99
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
group 0.370 None 0.875 7 0 1977 2019
Entrez Id: 1075
Gene Symbol: CTSC
CTSC
cathepsin C 0.541 0.731 1.1E-07
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
group 0.210 None 1.000 1 0 1978 2019
Entrez Id: 183
Gene Symbol: AGT
AGT
angiotensinogen 0.367 0.923 5.0E-08
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
group 0.600 None 0.971 702 21 1979 2020
Entrez Id: 5617
Gene Symbol: PRL
PRL
prolactin 0.406 0.885 2.9E-07
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
group 0.020 None 1.000 2 0 1980 2017
Entrez Id: 3827
Gene Symbol: KNG1
KNG1
kininogen 1 0.481 0.885 3.2E-10
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
group 0.400 None 1.000 15 2 1981 2019
Entrez Id: 7200
Gene Symbol: TRH
TRH
thyrotropin releasing hormone 0.519 0.846 8.9E-04
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
group 0.550 None 1.000 5 0 1983 2018
Entrez Id: 26
Gene Symbol: AOC1
AOC1
amine oxidase copper containing 1 0.628 0.769 6.7E-08
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
group 0.310 None 1.000 1 0 1983 2018
Entrez Id: 551
Gene Symbol: AVP
AVP
arginine vasopressin 0.437 0.846 7.4E-02
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
group 0.600 None 1.000 13 0 1984 2020
Entrez Id: 5340
Gene Symbol: PLG
PLG
plasminogen 0.389 0.923 1.0E-02
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
group 0.350 None 1.000 5 0 1984 2019
Entrez Id: 6366
Gene Symbol: CCL21
CCL21
C-C motif chemokine ligand 21 0.502 0.769 3.6E-02
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
group 0.020 None 1.000 2 0 1984 1997
Entrez Id: 2160
Gene Symbol: F11
F11
coagulation factor XI 0.590 0.692 3.6E-26
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
group 0.310 None 1.000 1 0 1984 2017
Entrez Id: 1636
Gene Symbol: ACE
ACE
angiotensin I converting enzyme 0.328 0.923 1.0E-37
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
group 0.600 None 0.921 523 15 1986 2020
Entrez Id: 2006
Gene Symbol: ELN
ELN
elastin 0.415 0.885 2.1E-14
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
group 0.500 None 1.000 16 0 1987 2019
Entrez Id: 1628
Gene Symbol: DBP
DBP
D-box binding PAR bZIP transcription factor 0.556 0.731 0.23
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
group 0.100 None 0.944 72 0 1988 2020
Entrez Id: 57338
Gene Symbol: JPH3
JPH3
junctophilin 3 0.608 0.538 1.00
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
group 0.030 None 1.000 3 0 1988 2019
Entrez Id: 106480993
Gene Symbol: RN7SL263P
RN7SL263P
RNA, 7SL, cytoplasmic 263, pseudogene 0.496 0.808
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
group 0.020 None 1.000 2 0 1988 1991
Entrez Id: 213
Gene Symbol: ALB
ALB
albumin 0.317 0.962 0.64
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
group 0.400 None 0.947 74 1 1989 2020
Entrez Id: 154
Gene Symbol: ADRB2
ADRB2
adrenoceptor beta 2 0.442 0.923 0.53
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
group 0.300 None 0.933 37 5 1989 2017
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
natriuretic peptide A 0.505 0.769 5.5E-04
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
group 0.600 None 0.970 24 3 1989 2019
Entrez Id: 4634
Gene Symbol: MYL3
MYL3
myosin light chain 3 0.695 0.308 8.8E-02
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
group 0.010 None 1.000 1 0 1989 1989
Entrez Id: 6866
Gene Symbol: TAC3
TAC3
tachykinin precursor 3 0.604 0.731 1.2E-02
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
group 0.210 None 1.000 1 0 1989 2000
Entrez Id: 790
Gene Symbol: CAD
CAD
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase 0.482 0.846 1.00
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
group 0.100 None 0.905 21 0 1990 2020