| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
proprotein convertase subtilisin/kexin type 9 | 0.482 | 0.808 | 2.7E-17 |
|
disease | 0.200 | None | 0.971 | 175 | 7 | 2003 | 2020 | ||||||||
|
apolipoprotein B | 0.453 | 0.808 | 1.9E-16 |
|
disease | 0.500 | None | 0.992 | 130 | 8 | 1988 | 2019 | ||||||||
|
lipoprotein(a) | 0.444 | 0.769 | 6.6E-89 |
|
disease | 0.100 | None | 0.973 | 37 | 1 | 1991 | 2019 | ||||||||
|
apolipoprotein E | 0.338 | 0.962 | 1.9E-03 |
|
disease | 0.600 | None | 0.889 | 18 | 6 | 1989 | 2020 | ||||||||
|
low density lipoprotein receptor adaptor protein 1 | 0.641 | 0.538 | 6.5E-06 |
|
disease | 0.100 | None | 1.000 | 12 | 1 | 2002 | 2019 | ||||||||
|
paraoxonase 1 | 0.409 | 0.885 | 9.8E-11 |
|
disease | 0.390 | None | 1.000 | 10 | 2 | 2000 | 2019 | ||||||||
|
lipoprotein lipase | 0.474 | 0.808 | 1.3E-09 |
|
disease | 0.380 | None | 1.000 | 9 | 3 | 1993 | 2016 | ||||||||
|
myosin binding protein C3 | 0.593 | 0.385 | 8.0E-11 |
|
disease | 0.080 | None | 0.875 | 8 | 1 | 1977 | 2005 | ||||||||
|
tropomyosin 1 | 0.560 | 0.615 | 1.0E-03 |
|
disease | 0.070 | None | 1.000 | 7 | 3 | 1994 | 2012 | ||||||||
|
cholesteryl ester transfer protein | 0.512 | 0.731 | 1.2E-23 |
|
disease | 0.360 | None | 1.000 | 7 | 1 | 1997 | 2011 | ||||||||
|
epidermal growth factor | 0.357 | 0.923 | 8.5E-17 |
|
disease | 0.060 | None | 1.000 | 6 | 0 | 1994 | 2015 | ||||||||
|
myosin heavy chain 7 | 0.516 | 0.692 | 4.2E-16 |
|
disease | 0.060 | None | 1.000 | 6 | 0 | 1994 | 2005 | ||||||||
|
apolipoprotein A1 | 0.429 | 0.885 | 5.5E-04 |
|
disease | 0.060 | None | 1.000 | 6 | 0 | 1998 | 2019 | ||||||||
|
signal transducing adaptor family member 1 | 0.792 | 0.231 | 1.7E-05 |
|
disease | 0.050 | None | 1.000 | 5 | 0 | 2014 | 2020 | ||||||||
|
3-hydroxy-3-methylglutaryl-CoA reductase | 0.529 | 0.692 | 1.00 |
|
disease | 0.340 | None | 1.000 | 5 | 1 | 1983 | 2016 | ||||||||
|
lipase A, lysosomal acid type | 0.564 | 0.654 | 5.5E-07 |
|
disease | 0.040 | None | 1.000 | 4 | 0 | 2016 | 2020 | ||||||||
|
troponin T2, cardiac type | 0.601 | 0.423 | 2.0E-03 |
|
disease | 0.030 | None | 1.000 | 3 | 2 | 1998 | 2006 | ||||||||
|
paraoxonase 2 | 0.566 | 0.808 | 5.4E-05 |
|
disease | 0.320 | None | 1.000 | 3 | 1 | 2001 | 2006 | ||||||||
|
hyperkeratosis lenticularis perstans | 0.691 | 0.346 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 2000 | 2017 | |||||||||
|
tumor necrosis factor | 0.231 | 0.962 | 0.80 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 2007 | 2013 | ||||||||
|
solute carrier organic anion transporter family member 1B1 | 0.538 | 0.731 | 1.1E-21 |
|
disease | 0.030 | None | 0.667 | 3 | 1 | 2012 | 2016 | ||||||||
|
troponin I3, cardiac type | 0.520 | 0.769 | 9.6E-02 |
|
disease | 0.030 | None | 1.000 | 3 | 3 | 2004 | 2008 | ||||||||
|
actin beta | 0.325 | 0.923 | 0.99 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 1993 | 2010 | ||||||||
|
angiopoietin like 3 | 0.584 | 0.577 | 1.6E-13 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 2017 | 2019 | ||||||||
|
ATP binding cassette subfamily G member 5 | 0.592 | 0.577 | 3.1E-21 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 2010 | 2018 |