Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3949
Gene Symbol: LDLR
LDLR
low density lipoprotein receptor 0.449 0.885 9.8E-24
CUI: C0745103
Disease: Hyperlipoproteinemia Type IIa
Hyperlipoproteinemia Type IIa
disease 0.800 strong 0.977 664 600 1975 2020
Entrez Id: 2053
Gene Symbol: EPHX2
EPHX2
epoxide hydrolase 2 0.568 0.654 1.8E-21
CUI: C0745103
Disease: Hyperlipoproteinemia Type IIa
Hyperlipoproteinemia Type IIa
disease 0.610 None 1.000 1 1 2004 2004
Entrez Id: 348
Gene Symbol: APOE
APOE
apolipoprotein E 0.338 0.962 1.9E-03
CUI: C0745103
Disease: Hyperlipoproteinemia Type IIa
Hyperlipoproteinemia Type IIa
disease 0.600 None 0.889 18 6 1989 2020
Entrez Id: 19
Gene Symbol: ABCA1
ABCA1
ATP binding cassette subfamily A member 1 0.467 0.846 1.5E-13
CUI: C0745103
Disease: Hyperlipoproteinemia Type IIa
Hyperlipoproteinemia Type IIa
disease 0.520 limited 1.000 3 0 2005 2019
Entrez Id: 336
Gene Symbol: APOA2
APOA2
apolipoprotein A2 0.582 0.769 4.5E-02
CUI: C0745103
Disease: Hyperlipoproteinemia Type IIa
Hyperlipoproteinemia Type IIa
disease 0.510 None 1.000 1 0 2002 2002
Entrez Id: 2690
Gene Symbol: GHR
GHR
growth hormone receptor 0.490 0.846 8.4E-05
CUI: C0745103
Disease: Hyperlipoproteinemia Type IIa
Hyperlipoproteinemia Type IIa
disease 0.510 None 1.000 1 1 2003 2003
Entrez Id: 338
Gene Symbol: APOB
APOB
apolipoprotein B 0.453 0.808 1.9E-16
CUI: C0745103
Disease: Hyperlipoproteinemia Type IIa
Hyperlipoproteinemia Type IIa
disease 0.500 None 0.992 130 8 1988 2019
Entrez Id: 5444
Gene Symbol: PON1
PON1
paraoxonase 1 0.409 0.885 9.8E-11
CUI: C0745103
Disease: Hyperlipoproteinemia Type IIa
Hyperlipoproteinemia Type IIa
disease 0.390 None 1.000 10 2 2000 2019
Entrez Id: 4023
Gene Symbol: LPL
LPL
lipoprotein lipase 0.474 0.808 1.3E-09
CUI: C0745103
Disease: Hyperlipoproteinemia Type IIa
Hyperlipoproteinemia Type IIa
disease 0.380 None 1.000 9 3 1993 2016
Entrez Id: 1071
Gene Symbol: CETP
CETP
cholesteryl ester transfer protein 0.512 0.731 1.2E-23
CUI: C0745103
Disease: Hyperlipoproteinemia Type IIa
Hyperlipoproteinemia Type IIa
disease 0.360 None 1.000 7 1 1997 2011
Entrez Id: 3156
Gene Symbol: HMGCR
HMGCR
3-hydroxy-3-methylglutaryl-CoA reductase 0.529 0.692 1.00
CUI: C0745103
Disease: Hyperlipoproteinemia Type IIa
Hyperlipoproteinemia Type IIa
disease 0.340 None 1.000 5 1 1983 2016
Entrez Id: 5445
Gene Symbol: PON2
PON2
paraoxonase 2 0.566 0.808 5.4E-05
CUI: C0745103
Disease: Hyperlipoproteinemia Type IIa
Hyperlipoproteinemia Type IIa
disease 0.320 None 1.000 3 1 2001 2006
Entrez Id: 337
Gene Symbol: APOA4
APOA4
apolipoprotein A4 0.582 0.577 5.5E-06
CUI: C0745103
Disease: Hyperlipoproteinemia Type IIa
Hyperlipoproteinemia Type IIa
disease 0.310 None 1.000 2 0 1998 2005
Entrez Id: 3990
Gene Symbol: LIPC
LIPC
lipase C, hepatic type 0.585 0.654 3.3E-07
CUI: C0745103
Disease: Hyperlipoproteinemia Type IIa
Hyperlipoproteinemia Type IIa
disease 0.310 None 1.000 2 0 2005 2014
Entrez Id: 345
Gene Symbol: APOC3
APOC3
apolipoprotein C3 0.531 0.731 1.0E-02
CUI: C0745103
Disease: Hyperlipoproteinemia Type IIa
Hyperlipoproteinemia Type IIa
disease 0.300 None 1.000 1 0 2005 2005
Entrez Id: 10842
Gene Symbol: PPP1R17
PPP1R17
protein phosphatase 1 regulatory subunit 17 0.805 0.192 1.0E-03
CUI: C0745103
Disease: Hyperlipoproteinemia Type IIa
Hyperlipoproteinemia Type IIa
disease 0.300 None 0 0
Entrez Id: 255738
Gene Symbol: PCSK9
PCSK9
proprotein convertase subtilisin/kexin type 9 0.482 0.808 2.7E-17
CUI: C0745103
Disease: Hyperlipoproteinemia Type IIa
Hyperlipoproteinemia Type IIa
disease 0.200 None 0.971 175 7 2003 2020
Entrez Id: 4018
Gene Symbol: LPA
LPA
lipoprotein(a) 0.444 0.769 6.6E-89
CUI: C0745103
Disease: Hyperlipoproteinemia Type IIa
Hyperlipoproteinemia Type IIa
disease 0.100 None 0.973 37 1 1991 2019
Entrez Id: 26119
Gene Symbol: LDLRAP1
LDLRAP1
low density lipoprotein receptor adaptor protein 1 0.641 0.538 6.5E-06
CUI: C0745103
Disease: Hyperlipoproteinemia Type IIa
Hyperlipoproteinemia Type IIa
disease 0.100 None 1.000 12 1 2002 2019
Entrez Id: 102465534
Gene Symbol: MIR6886
MIR6886
microRNA 6886 0.861 0.077
CUI: C0745103
Disease: Hyperlipoproteinemia Type IIa
Hyperlipoproteinemia Type IIa
disease 0.100 None 0 132
Entrez Id: 4607
Gene Symbol: MYBPC3
MYBPC3
myosin binding protein C3 0.593 0.385 8.0E-11
CUI: C0745103
Disease: Hyperlipoproteinemia Type IIa
Hyperlipoproteinemia Type IIa
disease 0.080 None 0.875 8 1 1977 2005
Entrez Id: 7168
Gene Symbol: TPM1
TPM1
tropomyosin 1 0.560 0.615 1.0E-03
CUI: C0745103
Disease: Hyperlipoproteinemia Type IIa
Hyperlipoproteinemia Type IIa
disease 0.070 None 1.000 7 3 1994 2012
Entrez Id: 4625
Gene Symbol: MYH7
MYH7
myosin heavy chain 7 0.516 0.692 4.2E-16
CUI: C0745103
Disease: Hyperlipoproteinemia Type IIa
Hyperlipoproteinemia Type IIa
disease 0.060 None 1.000 6 0 1994 2005
Entrez Id: 335
Gene Symbol: APOA1
APOA1
apolipoprotein A1 0.429 0.885 5.5E-04
CUI: C0745103
Disease: Hyperlipoproteinemia Type IIa
Hyperlipoproteinemia Type IIa
disease 0.060 None 1.000 6 0 1998 2019
Entrez Id: 1950
Gene Symbol: EGF
EGF
epidermal growth factor 0.357 0.923 8.5E-17
CUI: C0745103
Disease: Hyperlipoproteinemia Type IIa
Hyperlipoproteinemia Type IIa
disease 0.060 None 1.000 6 0 1994 2015