Source: CURATED

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3630
Gene Symbol: INS
INS 		insulin 0.445 0.923 0.30
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.700 None 0.978 10 1 1983 2020
Entrez Id: 3667
Gene Symbol: IRS1
IRS1 		insulin receptor substrate 1 0.488 0.769 2.4E-02
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.900 None 0.939 9 2 1993 2019
Entrez Id: 5468
Gene Symbol: PPARG
PPARG 		peroxisome proliferator activated receptor gamma 0.358 0.885 2.9E-02
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.700 None 0.953 6 10 1998 2020
Entrez Id: 6517
Gene Symbol: SLC2A4
SLC2A4 		solute carrier family 2 member 4 0.528 0.769 4.7E-05
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.800 None 0.951 6 1 1990 2020
Entrez Id: 169026
Gene Symbol: SLC30A8
SLC30A8 		solute carrier family 30 member 8 0.623 0.731 7.4E-12
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.500 None 0.963 6 6 2007 2019
Entrez Id: 6928
Gene Symbol: HNF1B
HNF1B 		HNF1 homeobox B 0.473 0.808 1.00
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.800 None 0.978 5 8 1998 2019
Entrez Id: 4544
Gene Symbol: MTNR1B
MTNR1B 		melatonin receptor 1B 0.588 0.731 6.5E-04
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.500 None 0.987 5 5 2008 2020
Entrez Id: 3172
Gene Symbol: HNF4A
HNF4A 		hepatocyte nuclear factor 4 alpha 0.461 0.808 0.15
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 1.000 None 0.942 5 8 1992 2019
Entrez Id: 208
Gene Symbol: AKT2
AKT2 		AKT serine/threonine kinase 2 0.474 0.769 0.64
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.960 None 1.000 4 1 2001 2018
Entrez Id: 3953
Gene Symbol: LEPR
LEPR 		leptin receptor 0.433 0.808 0.99
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.600 None 0.975 4 0 1966 2019
Entrez Id: 3643
Gene Symbol: INSR
INSR 		insulin receptor 0.432 0.846 3.6E-05
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.700 None 0.962 3 2 1985 2020
Entrez Id: 3990
Gene Symbol: LIPC
LIPC 		lipase C, hepatic type 0.585 0.654 3.3E-07
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.680 None 1.000 3 1 2001 2018
Entrez Id: 3784
Gene Symbol: KCNQ1
KCNQ1 		potassium voltage-gated channel subfamily Q member 1 0.485 0.769 4.5E-08
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.500 None 0.972 3 21 2008 2019
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1 		heme oxygenase 1 0.381 0.923 9.7E-03
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.600 None 0.950 3 0 2002 2019
Entrez Id: 6934
Gene Symbol: TCF7L2
TCF7L2 		transcription factor 7 like 2 0.485 0.846 1.00
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.700 None 0.965 3 14 2006 2020
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ 		adiponectin, C1Q and collagen domain containing 0.376 0.885 4.6E-09
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.600 None 0.950 3 0 1999 2020
Entrez Id: 54901
Gene Symbol: CDKAL1
CDKAL1 		CDK5 regulatory subunit associated protein 1 like 1 0.617 0.615 1.6E-02
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.700 None 0.984 3 88 2007 2019
Entrez Id: 847
Gene Symbol: CAT
CAT 		catalase 0.359 0.962 1.6E-10
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.400 None 0.952 2 0 1992 2019
Entrez Id: 6833
Gene Symbol: ABCC8
ABCC8 		ATP binding cassette subfamily C member 8 0.474 0.846 8.0E-24
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.700 None 0.900 2 8 1995 2018
Entrez Id: 407007
Gene Symbol: MIR222
MIR222 		microRNA 222 0.486 0.808
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.320 None 1.000 2 0 2014 2020
Entrez Id: 3651
Gene Symbol: PDX1
PDX1 		pancreatic and duodenal homeobox 1 0.530 0.654 1.8E-02
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.700 None 0.956 2 5 1998 2019
Entrez Id: 3636
Gene Symbol: INPPL1
INPPL1 		inositol polyphosphate phosphatase like 1 0.590 0.769 2.3E-03
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.400 None 1.000 2 0 2002 2020
Entrez Id: 111
Gene Symbol: ADCY5
ADCY5 		adenylate cyclase 5 0.617 0.577 1.00
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.700 None 0.947 2 3 2002 2019
Entrez Id: 10891
Gene Symbol: PPARGC1A
PPARGC1A 		PPARG coactivator 1 alpha 0.453 0.885 1.00
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.600 None 0.925 2 0 2001 2020
Entrez Id: 4846
Gene Symbol: NOS3
NOS3 		nitric oxide synthase 3 0.378 0.885 6.7E-07
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.600 None 0.900 2 0 1999 2019