Source: BEFREE

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta 0.319 0.885 1.00
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
disease 0.100 None 1.000 78 0 2012 2020
Entrez Id: 23291
Gene Symbol: FBXW11
FBXW11
F-box and WD repeat domain containing 11 0.626 0.462 0.98
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
disease 0.100 None 1.000 65 0 1988 2020
Entrez Id: 6910
Gene Symbol: TBX5
TBX5
T-box transcription factor 5 0.528 0.769 1.00
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
disease 0.100 None 1.000 65 0 1988 2020
Entrez Id: 596
Gene Symbol: BCL2
BCL2
BCL2 apoptosis regulator 0.291 0.885 0.56
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
disease 0.100 None 0.981 53 0 1995 2019
Entrez Id: 836
Gene Symbol: CASP3
CASP3
caspase 3 0.351 0.923 0.10
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
disease 0.100 None 1.000 45 0 2002 2020
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
signal transducer and activator of transcription 3 0.320 0.923 1.00
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
disease 0.100 None 1.000 44 0 2009 2020
Entrez Id: 207
Gene Symbol: AKT1
AKT1
AKT serine/threonine kinase 1 0.311 0.962 0.98
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
disease 0.100 None 1.000 43 0 2012 2020
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
matrix metallopeptidase 9 0.305 0.923 1.9E-17
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
disease 0.100 None 1.000 43 0 1990 2019
Entrez Id: 860
Gene Symbol: RUNX2
RUNX2
RUNX family transcription factor 2 0.437 0.846 0.95
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
disease 0.100 None 1.000 41 0 2000 2020
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
epidermal growth factor receptor 0.295 0.885 0.37
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
disease 0.100 None 0.974 39 0 1997 2019
Entrez Id: 7430
Gene Symbol: EZR
EZR
ezrin 0.476 0.808 0.18
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
disease 0.100 None 0.939 33 0 2003 2019
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
hypoxia inducible factor 1 subunit alpha 0.327 0.923 0.98
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
disease 0.100 None 1.000 32 0 2006 2019
Entrez Id: 407040
Gene Symbol: MIR34A
MIR34A
microRNA 34a 0.421 0.846
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
disease 0.100 None 1.000 31 0 2009 2019
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
mitogen-activated protein kinase 1 0.330 0.923 1.00
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
disease 0.100 None 1.000 30 0 1994 2019
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
phosphatase and tensin homolog 0.305 0.923 0.26
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
disease 0.100 None 0.931 29 0 2011 2020
Entrez Id: 632
Gene Symbol: BGLAP
BGLAP
bone gamma-carboxyglutamate protein 0.462 0.846 4.6E-08
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
disease 0.100 None 1.000 29 0 1990 2019
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
cyclin dependent kinase inhibitor 2A 0.300 0.885 0.39
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
disease 0.100 None 0.920 25 0 1995 2019
Entrez Id: 29126
Gene Symbol: CD274
CD274
CD274 molecule 0.324 0.923 1.9E-02
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
disease 0.100 None 1.000 23 0 2014 2019
Entrez Id: 55000
Gene Symbol: TUG1
TUG1
taurine up-regulated 1 0.522 0.769
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
disease 0.100 None 1.000 22 0 2013 2020
Entrez Id: 6093
Gene Symbol: ROCK1
ROCK1
Rho associated coiled-coil containing protein kinase 1 0.513 0.731 1.00
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
disease 0.100 None 1.000 22 0 2011 2019
Entrez Id: 6935
Gene Symbol: ZEB1
ZEB1
zinc finger E-box binding homeobox 1 0.442 0.808 0.97
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
disease 0.100 None 1.000 22 0 2010 2020
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
estrogen receptor 1 0.324 0.962 1.00
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
disease 0.100 None 1.000 20 0 1988 2019
Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
metastasis associated lung adenocarcinoma transcript 1 0.435 0.846
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
disease 0.100 None 1.000 20 0 2015 2019
Entrez Id: 7852
Gene Symbol: CXCR4
CXCR4
C-X-C motif chemokine receptor 4 0.362 0.923 1.8E-02
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
disease 0.100 None 0.950 20 0 2005 2020
Entrez Id: 406991
Gene Symbol: MIR21
MIR21
microRNA 21 0.363 0.846
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
disease 0.100 None 1.000 19 0 2011 2019