| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
amyloid beta precursor protein | 0.422 | 0.846 | 4.7E-02 |
|
disease | 0.400 | None | 0.988 | 162 | 5 | 1988 | 2020 | ||||||||
|
apolipoprotein E | 0.338 | 0.962 | 1.9E-03 |
|
disease | 0.200 | None | 0.921 | 76 | 0 | 1993 | 2019 | ||||||||
|
microtubule associated protein tau | 0.446 | 0.923 | 6.0E-03 |
|
disease | 0.200 | None | 1.000 | 43 | 1 | 1993 | 2019 | ||||||||
|
beta-secretase 1 | 0.559 | 0.769 | 0.88 |
|
disease | 0.100 | None | 1.000 | 20 | 0 | 2004 | 2019 | ||||||||
|
presenilin 1 | 0.469 | 0.846 | 0.97 |
|
disease | 0.200 | None | 1.000 | 15 | 3 | 1996 | 2018 | ||||||||
|
succinate-CoA ligase ADP-forming subunit beta | 0.566 | 0.654 | 2.3E-03 |
|
disease | 0.100 | None | 1.000 | 10 | 0 | 2011 | 2019 | ||||||||
|
prion protein | 0.445 | 0.923 | 6.3E-04 |
|
disease | 0.200 | None | 0.900 | 10 | 1 | 1991 | 2020 | ||||||||
|
synuclein alpha | 0.427 | 0.885 | 0.88 |
|
disease | 0.080 | None | 1.000 | 8 | 0 | 1999 | 2018 | ||||||||
|
glial fibrillary acidic protein | 0.421 | 0.885 | 1.5E-06 |
|
disease | 0.070 | None | 1.000 | 7 | 0 | 1987 | 2016 | ||||||||
|
brain derived neurotrophic factor | 0.345 | 0.923 | 0.66 |
|
disease | 0.060 | None | 1.000 | 6 | 0 | 2013 | 2019 | ||||||||
|
serpin family A member 3 | 0.486 | 0.846 | 8.8E-14 |
|
disease | 0.050 | None | 1.000 | 5 | 0 | 1997 | 2004 | ||||||||
|
insulin degrading enzyme | 0.604 | 0.577 | 6.6E-03 |
|
disease | 0.050 | None | 1.000 | 5 | 0 | 2003 | 2010 | ||||||||
|
S100 calcium binding protein B | 0.383 | 0.923 | 4.4E-02 |
|
disease | 0.040 | None | 1.000 | 4 | 0 | 1995 | 2018 | ||||||||
|
interleukin 6 | 0.248 | 0.962 | 0.32 |
|
disease | 0.040 | None | 1.000 | 4 | 0 | 2000 | 2017 | ||||||||
|
tumor necrosis factor | 0.231 | 0.962 | 0.80 |
|
disease | 0.040 | None | 1.000 | 4 | 0 | 2000 | 2018 | ||||||||
|
caspase 3 | 0.351 | 0.923 | 0.10 |
|
disease | 0.040 | None | 0.750 | 4 | 0 | 1999 | 2016 | ||||||||
|
myeloperoxidase | 0.377 | 0.923 | 7.1E-15 |
|
disease | 0.040 | None | 1.000 | 4 | 0 | 1999 | 2019 | ||||||||
|
ADAM metallopeptidase domain 10 | 0.489 | 0.846 | 1.00 |
|
disease | 0.040 | None | 1.000 | 4 | 0 | 2012 | 2019 | ||||||||
|
membrane metalloendopeptidase | 0.407 | 0.808 | 1.5E-18 |
|
disease | 0.040 | None | 0.750 | 4 | 0 | 2001 | 2010 | ||||||||
|
ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.397 | 0.923 | 2.5E-02 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 2004 | 2017 | ||||||||
|
mitogen-activated protein kinase 1 | 0.330 | 0.923 | 1.00 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 2004 | 2017 | ||||||||
|
heme oxygenase 1 | 0.381 | 0.923 | 9.7E-03 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 2000 | 2016 | ||||||||
|
reticulon 3 | 0.647 | 0.615 | 6.6E-05 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 2017 | 2018 | ||||||||
|
CRK proto-oncogene, adaptor protein | 0.394 | 0.923 | 0.96 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 2004 | 2017 | ||||||||
|
C-reactive protein | 0.299 | 0.962 | 3.7E-03 |
|
disease | 0.030 | None | 1.000 | 3 | 2 | 2004 | 2011 |