| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
tumor necrosis factor | 0.231 | 0.962 | 0.80 |
|
disease | 0.040 | None | 1.000 | 4 | 0 | 2000 | 2018 | ||||||||
|
interleukin 6 | 0.248 | 0.962 | 0.32 |
|
disease | 0.040 | None | 1.000 | 4 | 0 | 2000 | 2017 | ||||||||
|
interleukin 1 beta | 0.276 | 0.962 | 0.13 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 2000 | 2018 | ||||||||
|
interleukin 10 | 0.281 | 0.923 | 5.9E-03 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2001 | 2001 | ||||||||
|
transforming growth factor beta 1 | 0.287 | 0.962 | 3.7E-02 |
|
disease | 0.020 | None | 0.500 | 2 | 0 | 1995 | 2000 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 0.292 | 0.923 | 1.00 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2018 | 2019 | ||||||||
|
C-reactive protein | 0.299 | 0.962 | 3.7E-03 |
|
disease | 0.030 | None | 1.000 | 3 | 2 | 2004 | 2011 | ||||||||
|
phosphatase and tensin homolog | 0.305 | 0.923 | 0.26 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2013 | 2013 | ||||||||
|
AKT serine/threonine kinase 1 | 0.311 | 0.962 | 0.98 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2018 | 2018 | ||||||||
|
albumin | 0.317 | 0.962 | 0.64 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2013 | 2013 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta | 0.319 | 0.885 | 1.00 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2018 | 2019 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma | 0.320 | 0.885 | 1.4E-06 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2018 | 2019 | ||||||||
|
C-C motif chemokine ligand 2 | 0.321 | 0.962 | 0.61 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2000 | 2004 | ||||||||
|
toll like receptor 4 | 0.321 | 0.962 | 4.6E-09 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2012 | 2012 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta | 0.322 | 0.885 | 1.00 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2018 | 2019 | ||||||||
|
actin beta | 0.325 | 0.923 | 0.99 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 1998 | 1998 | ||||||||
|
angiotensin I converting enzyme | 0.328 | 0.923 | 1.0E-37 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2015 | 2015 | ||||||||
|
mitogen-activated protein kinase 1 | 0.330 | 0.923 | 1.00 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 2004 | 2017 | ||||||||
|
interleukin 4 | 0.332 | 0.962 | 4.7E-03 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2002 | 2002 | ||||||||
|
interleukin 1 alpha | 0.333 | 0.962 | 1.6E-04 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2000 | 2002 | ||||||||
|
interleukin 2 | 0.336 | 0.885 | 0.48 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2017 | 2017 | ||||||||
|
apolipoprotein E | 0.338 | 0.962 | 1.9E-03 |
|
disease | 0.200 | None | 0.921 | 76 | 0 | 1993 | 2019 | ||||||||
|
mechanistic target of rapamycin kinase | 0.343 | 0.885 | 1.00 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2018 | 2018 | ||||||||
|
cyclin D1 | 0.344 | 0.923 | 0.89 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2004 | 2004 | ||||||||
|
brain derived neurotrophic factor | 0.345 | 0.923 | 0.66 |
|
disease | 0.060 | None | 1.000 | 6 | 0 | 2013 | 2019 |