| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
BRCA1 DNA repair associated | 0.367 | 0.923 | 9.2E-29 |
|
disease | 0.800 | strong | 0.965 | 1346 | 23 | 1992 | 2020 | ||||||||
|
tumor protein p53 | 0.236 | 0.962 | 0.53 |
|
disease | 0.700 | None | 0.958 | 261 | 10 | 1991 | 2020 | ||||||||
|
BRCA2 DNA repair associated | 0.379 | 0.846 | 2.4E-25 |
|
disease | 0.800 | strong | 0.948 | 679 | 5 | 1994 | 2020 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 0.292 | 0.923 | 1.00 |
|
disease | 0.700 | None | 0.986 | 72 | 5 | 1999 | 2019 | ||||||||
|
checkpoint kinase 2 | 0.460 | 0.808 | 1.2E-24 |
|
disease | 0.200 | None | 0.769 | 13 | 5 | 2003 | 2019 | ||||||||
|
APC regulator of WNT signaling pathway | 0.373 | 0.962 | 1.00 |
|
disease | 0.360 | None | 1.000 | 6 | 5 | 1994 | 2019 | ||||||||
|
progesterone receptor | 0.426 | 0.885 | 5.1E-02 |
|
disease | 0.100 | None | 1.000 | 27 | 4 | 1995 | 2019 | ||||||||
|
estrogen receptor 2 | 0.400 | 0.923 | 4.5E-08 |
|
disease | 0.100 | None | 1.000 | 18 | 4 | 2004 | 2019 | ||||||||
|
vascular endothelial growth factor A | 0.266 | 0.923 | 2.4E-05 |
|
disease | 0.100 | None | 0.974 | 77 | 3 | 1995 | 2019 | ||||||||
|
epidermal growth factor receptor | 0.295 | 0.885 | 0.37 |
|
disease | 0.400 | None | 0.982 | 55 | 3 | 1990 | 2019 | ||||||||
|
ATP binding cassette subfamily B member 1 | 0.344 | 0.885 | 1.3E-05 |
|
disease | 0.100 | None | 1.000 | 46 | 3 | 1989 | 2019 | ||||||||
|
mutL homolog 1 | 0.399 | 0.808 | 3.4E-05 |
|
disease | 0.700 | strong | 0.900 | 20 | 3 | 1994 | 2019 | ||||||||
|
methylenetetrahydrofolate reductase | 0.337 | 0.885 | 3.2E-10 |
|
disease | 0.100 | None | 0.786 | 14 | 3 | 1997 | 2017 | ||||||||
|
HOX transcript antisense RNA | 0.475 | 0.769 |
|
disease | 0.100 | None | 1.000 | 13 | 3 | 2015 | 2019 | |||||||||
|
nuclear factor kappa B subunit 1 | 0.396 | 0.923 | 1.00 |
|
disease | 0.080 | None | 1.000 | 8 | 3 | 2006 | 2018 | ||||||||
|
prostate cancer associated transcript 1 | 0.575 | 0.615 |
|
disease | 0.040 | None | 1.000 | 4 | 3 | 2019 | 2020 | |||||||||
|
8-oxoguanine DNA glycosylase | 0.453 | 0.808 | 3.9E-12 |
|
disease | 0.030 | None | 1.000 | 3 | 3 | 2005 | 2016 | ||||||||
|
chorionic gonadotropin subunit beta 5 | 0.579 | 0.654 | 2.5E-02 |
|
disease | 0.030 | None | 1.000 | 3 | 3 | 1997 | 2019 | ||||||||
|
ADP ribosylation factor like GTPase 11 | 0.670 | 0.423 | 5.3E-03 |
|
disease | 0.320 | None | 1.000 | 2 | 3 | 2006 | 2009 | ||||||||
|
cancer susceptibility 8 | 0.670 | 0.462 |
|
disease | 0.010 | None | 1.000 | 1 | 3 | 2016 | 2016 | |||||||||
|
erb-b2 receptor tyrosine kinase 2 | 0.328 | 0.923 | 6.0E-03 |
|
disease | 0.700 | None | 0.970 | 130 | 2 | 1989 | 2019 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta | 0.322 | 0.885 | 1.00 |
|
disease | 0.100 | None | 1.000 | 53 | 2 | 2001 | 2019 | ||||||||
|
RAD51 paralog C | 0.533 | 0.692 | 6.2E-14 |
|
disease | 0.700 | strong | 0.947 | 38 | 2 | 2010 | 2020 | ||||||||
|
KRAS proto-oncogene, GTPase | 0.320 | 0.923 | 7.9E-04 |
|
disease | 0.700 | None | 0.909 | 21 | 2 | 1986 | 2019 | ||||||||
|
B-Raf proto-oncogene, serine/threonine kinase | 0.319 | 0.846 | 1.00 |
|
disease | 0.600 | None | 0.941 | 17 | 2 | 2003 | 2019 |