×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
Lung cancer cells expressing oncogenic K-Ras have bypassed the senescence barrier.29247004 2018
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
A functional switch from lung cancer resistance to susceptibility at the Pas1 locus in Kras2LA2 mice.
16823377 2006
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
A mouse model for tumor progression of lung cancer in ras and p53 transgenic mice.
16247444 2006
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
Benzo[b]fluoranthene: tumorigenicity in strain A/J mouse lungs, DNA adducts and mutations in the Ki-ras oncogene.
8761429 1996
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
Cigarette smoking is strongly associated with mutation of the K-ras gene in patients with primary adenocarcinoma of the lung.
11745231 2001
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
Codon 12 region of mouse K-ras gene is the site for in vitro binding of transcription factors GATA-6 and NF-Y.
16271038 2005
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma.
26390243 2015
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
CRM1-dependent p53 nuclear accumulation in lung lesions of a bitransgenic mouse lung tumor model.
21519798 2011
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
Decrease in K-ras p21 and increase in Raf1 and activated Erk 1 and 2 in murine lung tumors initiated by N-nitrosodimethylamine and promoted by 2,3,7,8-tetrachlorodibenzo-p-dioxin.
11884234 2002
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
DNA adduct measurements, cell proliferation and tumor mutation induction in relation to tumor formation in B6C3F1 mice fed coal tar or benzo[a]pyrene.
10874023 2000
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
Downregulation of RECK by promoter methylation correlates with lymph node metastasis in non-small cell lung cancer.
17233834 2007
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
Gene expression analysis of urethane-induced lung tumors in ras H2 mice.
16289808 2006
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
Genetic alterations in cancer knowledge system: analysis of gene mutations in mouse and human liver and lung tumors.
16410370 2006
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
Genetically engineered murine models of mutant EGFR and KRAS have been developed that more accurately recapitulate human lung cancer .
18927287 2008
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
Heterozygous inactivation of TGF-beta1 increases the susceptibility to chemically induced mouse lung tumorigenesis independently of mutational activation of K-ras.
11641043 2001
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
High frequency of codon 61 K-ras A-->T transversions in lung and Harderian gland neoplasms of B6C3F1 mice exposed to chloroprene (2-chloro-1,3-butadiene) for 2 years, and comparisons with the structurally related chemicals isoprene and 1,3-butadiene.
10223196 1999
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
Human lung cancer patients exhibit different KRAS mutations depending on smoking status.
20101149 2010
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
Identification and characterization of mechanism of action of P61-E7, a novel phosphine catalysis-based inhibitor of geranylgeranyltransferase-I.
22028818 2011
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
Immunomodulatory activities of Punarnavine, an alkaloid from Boerhaavia diffusa.
19555203 2009
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
In this study, we demonstrate that K-Ras , a frequently altered oncogene in human cancers including pancreatic cancer (about 80%), colon cancer (45%) and lung cancer (45%), suppresses p53.
19424582 2009
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
Increased frequency of K-ras mutations in lung neoplasms from female B6C3F1 mice exposed to ozone for 24 or 30 months.
7614698 1995
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
K-ras mutations in benzotrichloride-induced lung tumors of A/J mice.
8508514 1993
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
K-ras mutations in lung tumors and tumors from other organs are consistent with a common mechanism of ethylene oxide tumorigenesis in the B6C3F1 mouse.
17325976 2007
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
Kras regulatory elements and exon 4A determine mutation specificity in lung cancer.
18758463 2008
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
Long-term toxicity studies of ozone in F344/N rats and B6C3F1 mice.
8597069 1995