×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
Increased frequency of K-ras mutations in lung neoplasms from female B6C3F1 mice exposed to ozone for 24 or 30 months.
7614698 1995
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
Long-term toxicity studies of ozone in F344/N rats and B6C3F1 mice.
8597069 1995
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
Lung cancer cells expressing oncogenic K-Ras have bypassed the senescence barrier.29247004 2018
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
[K-ras gene mutations of asbestos and welding-fumes related human lung cancer ].
12725029 2000
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
The Egfr and K-ras gene mutations were detected at sites also found in human lung cancers with low incidences, while the Egfr gene mutation was detected for the first time in chemical lung carcinogenesis of animals.
19336973 2009
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
Heterozygous inactivation of TGF-beta1 increases the susceptibility to chemically induced mouse lung tumorigenesis independently of mutational activation of K-ras.
11641043 2001
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
Genetic alterations in cancer knowledge system: analysis of gene mutations in mouse and human liver and lung tumors.
16410370 2006
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
Kras regulatory elements and exon 4A determine mutation specificity in lung cancer.
18758463 2008
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
Lung cancer in never smokers: a review.
17290066 2007
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
In this study, we demonstrate that K-Ras , a frequently altered oncogene in human cancers including pancreatic cancer (about 80%), colon cancer (45%) and lung cancer (45%), suppresses p53.
19424582 2009
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
A mouse model for tumor progression of lung cancer in ras and p53 transgenic mice.
16247444 2006
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
Downregulation of RECK by promoter methylation correlates with lymph node metastasis in non-small cell lung cancer.
17233834 2007
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
High frequency of codon 61 K-ras A-->T transversions in lung and Harderian gland neoplasms of B6C3F1 mice exposed to chloroprene (2-chloro-1,3-butadiene) for 2 years, and comparisons with the structurally related chemicals isoprene and 1,3-butadiene.
10223196 1999
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
K-ras mutations in lung tumors and tumors from other organs are consistent with a common mechanism of ethylene oxide tumorigenesis in the B6C3F1 mouse.
17325976 2007
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
Benzo[b]fluoranthene: tumorigenicity in strain A/J mouse lungs, DNA adducts and mutations in the Ki-ras oncogene.
8761429 1996
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
Decrease in K-ras p21 and increase in Raf1 and activated Erk 1 and 2 in murine lung tumors initiated by N-nitrosodimethylamine and promoted by 2,3,7,8-tetrachlorodibenzo-p-dioxin.
11884234 2002
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
Mutations of the Ki-ras protooncogene in 3-methylcholanthrene and urethan-induced and butylated hydroxytoluene-promoted lung tumors of strain A/J and SWR mice.
7750092 1995
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
Codon 12 region of mouse K-ras gene is the site for in vitro binding of transcription factors GATA-6 and NF-Y.
16271038 2005
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
A functional switch from lung cancer resistance to susceptibility at the Pas1 locus in Kras2LA2 mice.
16823377 2006
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
Identification and characterization of mechanism of action of P61-E7, a novel phosphine catalysis-based inhibitor of geranylgeranyltransferase-I.
22028818 2011
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
Cigarette smoking is strongly associated with mutation of the K-ras gene in patients with primary adenocarcinoma of the lung.
11745231 2001
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
The E3 ubiquitin ligase Trim7 mediates c-Jun/AP-1 activation by Ras signalling.
25851810 2015
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
CRM1-dependent p53 nuclear accumulation in lung lesions of a bitransgenic mouse lung tumor model.
21519798 2011
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
DNA adduct measurements, cell proliferation and tumor mutation induction in relation to tumor formation in B6C3F1 mice fed coal tar or benzo[a]pyrene.
10874023 2000
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
Immunomodulatory activities of Punarnavine, an alkaloid from Boerhaavia diffusa.
19555203 2009