Source: BEFREE

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
transforming growth factor beta 1 0.287 0.962 3.7E-02
CUI: C0041956
Disease: Ureteral obstruction
Ureteral obstruction
phenotype 0.400 None 1.000 49 0 1999 2020
Entrez Id: 2335
Gene Symbol: FN1
FN1
fibronectin 1 0.365 0.962 1.4E-03
CUI: C0041956
Disease: Ureteral obstruction
Ureteral obstruction
phenotype 0.400 None 1.000 24 0 2012 2020
Entrez Id: 60
Gene Symbol: ACTB
ACTB
actin beta 0.325 0.923 0.99
CUI: C0041956
Disease: Ureteral obstruction
Ureteral obstruction
phenotype 0.100 None 1.000 12 0 2012 2020
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
C-C motif chemokine ligand 2 0.321 0.962 0.61
CUI: C0041956
Disease: Ureteral obstruction
Ureteral obstruction
phenotype 0.400 None 1.000 10 0 2007 2019
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
interleukin 1 beta 0.276 0.962 0.13
CUI: C0041956
Disease: Ureteral obstruction
Ureteral obstruction
phenotype 0.100 None 1.000 10 0 2010 2019
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
nuclear factor, erythroid 2 like 2 0.357 0.885 3.6E-03
CUI: C0041956
Disease: Ureteral obstruction
Ureteral obstruction
phenotype 0.100 None 1.000 10 0 2012 2019
Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3
SMAD family member 3 0.415 0.923 0.80
CUI: C0041956
Disease: Ureteral obstruction
Ureteral obstruction
phenotype 0.390 None 1.000 9 0 2012 2019
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3
NLR family pyrin domain containing 3 0.361 0.962 8.1E-04
CUI: C0041956
Disease: Ureteral obstruction
Ureteral obstruction
phenotype 0.090 None 1.000 9 0 2010 2020
Entrez Id: 6606
Gene Symbol: SMN1
SMN1
survival of motor neuron 1, telomeric 0.454 0.769 1.6E-02
CUI: C0041956
Disease: Ureteral obstruction
Ureteral obstruction
phenotype 0.080 None 1.000 8 0 2013 2019
Entrez Id: 6607
Gene Symbol: SMN2
SMN2
survival of motor neuron 2, centromeric 0.459 0.769 0.10
CUI: C0041956
Disease: Ureteral obstruction
Ureteral obstruction
phenotype 0.080 None 1.000 8 0 2013 2019
Entrez Id: 1490
Gene Symbol: CCN2
CCN2
cellular communication network factor 2 0.399 0.846 5.0E-04
CUI: C0041956
Disease: Ureteral obstruction
Ureteral obstruction
phenotype 0.080 None 1.000 8 0 2012 2019
Entrez Id: 4087
Gene Symbol: SMAD2
SMAD2
SMAD family member 2 0.456 0.808 1.00
CUI: C0041956
Disease: Ureteral obstruction
Ureteral obstruction
phenotype 0.070 None 1.000 7 0 2013 2019
Entrez Id: 5972
Gene Symbol: REN
REN
renin 0.370 0.923 2.4E-07
CUI: C0041956
Disease: Ureteral obstruction
Ureteral obstruction
phenotype 0.070 None 1.000 7 0 1996 2019
Entrez Id: 2551
Gene Symbol: GABPA
GABPA
GA binding protein transcription factor subunit alpha 0.379 0.885 1.00
CUI: C0041956
Disease: Ureteral obstruction
Ureteral obstruction
phenotype 0.070 None 1.000 7 0 2012 2019
Entrez Id: 203447
Gene Symbol: NRK
NRK
Nik related kinase 0.666 0.538 0.99
CUI: C0041956
Disease: Ureteral obstruction
Ureteral obstruction
phenotype 0.070 None 1.000 7 0 2017 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF
tumor necrosis factor 0.231 0.962 0.80
CUI: C0041956
Disease: Ureteral obstruction
Ureteral obstruction
phenotype 0.060 None 1.000 6 0 2017 2019
Entrez Id: 9365
Gene Symbol: KL
KL
klotho 0.448 0.769 2.2E-04
CUI: C0041956
Disease: Ureteral obstruction
Ureteral obstruction
phenotype 0.060 None 1.000 6 0 2011 2019
Entrez Id: 50507
Gene Symbol: NOX4
NOX4
NADPH oxidase 4 0.471 0.885 5.8E-20
CUI: C0041956
Disease: Ureteral obstruction
Ureteral obstruction
phenotype 0.060 None 1.000 6 0 2016 2019
Entrez Id: 7431
Gene Symbol: VIM
VIM
vimentin 0.372 0.846 0.71
CUI: C0041956
Disease: Ureteral obstruction
Ureteral obstruction
phenotype 0.050 None 1.000 5 0 2017 2019
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta 0.322 0.885 1.00
CUI: C0041956
Disease: Ureteral obstruction
Ureteral obstruction
phenotype 0.050 None 1.000 5 0 2015 2019
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
signal transducer and activator of transcription 3 0.320 0.923 1.00
CUI: C0041956
Disease: Ureteral obstruction
Ureteral obstruction
phenotype 0.050 None 1.000 5 0 2017 2019
Entrez Id: 3082
Gene Symbol: HGF
HGF
hepatocyte growth factor 0.374 0.885 1.00
CUI: C0041956
Disease: Ureteral obstruction
Ureteral obstruction
phenotype 0.050 None 1.000 5 0 2016 2019
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
hypoxia inducible factor 1 subunit alpha 0.327 0.923 0.98
CUI: C0041956
Disease: Ureteral obstruction
Ureteral obstruction
phenotype 0.050 None 0.800 5 0 2012 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha 0.292 0.923 1.00
CUI: C0041956
Disease: Ureteral obstruction
Ureteral obstruction
phenotype 0.050 None 1.000 5 0 2015 2019
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta 0.319 0.885 1.00
CUI: C0041956
Disease: Ureteral obstruction
Ureteral obstruction
phenotype 0.050 None 1.000 5 0 2015 2019