Source: BEFREE

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3248
Gene Symbol: HPGD
HPGD
15-hydroxyprostaglandin dehydrogenase 0.516 0.731 1.4E-05
CUI: C0041956
Disease: Ureteral obstruction
Ureteral obstruction
phenotype 0.010 None 1.000 1 0 2004 2004
Entrez Id: 1666
Gene Symbol: DECR1
DECR1
2,4-dienoyl-CoA reductase 1 0.426 0.885 4.5E-14
CUI: C0041956
Disease: Ureteral obstruction
Ureteral obstruction
phenotype 0.010 None 1.000 1 0 2017 2017
Entrez Id: 60
Gene Symbol: ACTB
ACTB
actin beta 0.325 0.923 0.99
CUI: C0041956
Disease: Ureteral obstruction
Ureteral obstruction
phenotype 0.100 None 1.000 12 0 2012 2020
Entrez Id: 10598
Gene Symbol: AHSA1
AHSA1
activator of HSP90 ATPase activity 1 0.396 0.923 1.00
CUI: C0041956
Disease: Ureteral obstruction
Ureteral obstruction
phenotype 0.010 None 1.000 1 0 2019 2019
Entrez Id: 102
Gene Symbol: ADAM10
ADAM10
ADAM metallopeptidase domain 10 0.489 0.846 1.00
CUI: C0041956
Disease: Ureteral obstruction
Ureteral obstruction
phenotype 0.010 None 1.000 1 0 2018 2018
Entrez Id: 9510
Gene Symbol: ADAMTS1
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif 1 0.555 0.654 0.72
CUI: C0041956
Disease: Ureteral obstruction
Ureteral obstruction
phenotype 0.010 None 1.000 1 0 2007 2007
Entrez Id: 135
Gene Symbol: ADORA2A
ADORA2A
adenosine A2a receptor 0.526 0.769 0.60
CUI: C0041956
Disease: Ureteral obstruction
Ureteral obstruction
phenotype 0.010 None 1.000 1 0 2013 2013
Entrez Id: 133
Gene Symbol: ADM
ADM
adrenomedullin 0.436 0.808 4.1E-02
CUI: C0041956
Disease: Ureteral obstruction
Ureteral obstruction
phenotype 0.010 None 1.000 1 0 2008 2008
Entrez Id: 79924
Gene Symbol: ADM2
ADM2
adrenomedullin 2 0.711 0.462 2.0E-02
CUI: C0041956
Disease: Ureteral obstruction
Ureteral obstruction
phenotype 0.020 None 1.000 2 0 2017 2019
Entrez Id: 207
Gene Symbol: AKT1
AKT1
AKT serine/threonine kinase 1 0.311 0.962 0.98
CUI: C0041956
Disease: Ureteral obstruction
Ureteral obstruction
phenotype 0.010 None 1.000 1 0 2019 2019
Entrez Id: 208
Gene Symbol: AKT2
AKT2
AKT serine/threonine kinase 2 0.474 0.769 0.64
CUI: C0041956
Disease: Ureteral obstruction
Ureteral obstruction
phenotype 0.010 None 1.000 1 0 2014 2014
Entrez Id: 217
Gene Symbol: ALDH2
ALDH2
aldehyde dehydrogenase 2 family member 0.457 0.885 3.4E-10
CUI: C0041956
Disease: Ureteral obstruction
Ureteral obstruction
phenotype 0.010 None 1.000 1 0 2019 2019
Entrez Id: 7965
Gene Symbol: AIMP2
AIMP2
aminoacyl tRNA synthetase complex interacting multifunctional protein 2 0.393 0.923 8.0E-03
CUI: C0041956
Disease: Ureteral obstruction
Ureteral obstruction
phenotype 0.010 None 1.000 1 0 2019 2019
Entrez Id: 374
Gene Symbol: AREG
AREG
amphiregulin 0.487 0.769 0.35
CUI: C0041956
Disease: Ureteral obstruction
Ureteral obstruction
phenotype 0.010 None 1.000 1 0 2019 2019
Entrez Id: 284
Gene Symbol: ANGPT1
ANGPT1
angiopoietin 1 0.446 0.808 0.95
CUI: C0041956
Disease: Ureteral obstruction
Ureteral obstruction
phenotype 0.010 None 1.000 1 0 2018 2018
Entrez Id: 285
Gene Symbol: ANGPT2
ANGPT2
angiopoietin 2 0.410 0.846 0.83
CUI: C0041956
Disease: Ureteral obstruction
Ureteral obstruction
phenotype 0.010 None 1.000 1 0 2015 2015
Entrez Id: 1636
Gene Symbol: ACE
ACE
angiotensin I converting enzyme 0.328 0.923 1.0E-37
CUI: C0041956
Disease: Ureteral obstruction
Ureteral obstruction
phenotype 0.010 None 1.000 1 0 2018 2018
Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
angiotensin II receptor type 1 0.423 0.846 5.3E-04
CUI: C0041956
Disease: Ureteral obstruction
Ureteral obstruction
phenotype 0.030 None 1.000 3 0 2017 2019
Entrez Id: 183
Gene Symbol: AGT
AGT
angiotensinogen 0.367 0.923 5.0E-08
CUI: C0041956
Disease: Ureteral obstruction
Ureteral obstruction
phenotype 0.340 None 1.000 4 0 2012 2018
Entrez Id: 8862
Gene Symbol: APLN
APLN
apelin 0.497 0.769 0.46
CUI: C0041956
Disease: Ureteral obstruction
Ureteral obstruction
phenotype 0.010 None 1.000 1 0 2014 2014
Entrez Id: 8542
Gene Symbol: APOL1
APOL1
apolipoprotein L1 0.547 0.615 5.1E-06
CUI: C0041956
Disease: Ureteral obstruction
Ureteral obstruction
phenotype 0.010 None 1.000 1 0 2018 2018
Entrez Id: 328
Gene Symbol: APEX1
APEX1
apurinic/apyrimidinic endodeoxyribonuclease 1 0.458 0.846 1.9E-07
CUI: C0041956
Disease: Ureteral obstruction
Ureteral obstruction
phenotype 0.010 None 1.000 1 0 2019 2019
Entrez Id: 359
Gene Symbol: AQP2
AQP2
aquaporin 2 0.581 0.769 2.5E-06
CUI: C0041956
Disease: Ureteral obstruction
Ureteral obstruction
phenotype 0.040 None 0.750 4 0 2018 2020
Entrez Id: 240
Gene Symbol: ALOX5
ALOX5
arachidonate 5-lipoxygenase 0.447 0.885 1.2E-06
CUI: C0041956
Disease: Ureteral obstruction
Ureteral obstruction
phenotype 0.010 None 1.000 1 0 2019 2019
Entrez Id: 408
Gene Symbol: ARRB1
ARRB1
arrestin beta 1 0.588 0.846 0.99
CUI: C0041956
Disease: Ureteral obstruction
Ureteral obstruction
phenotype 0.010 None 1.000 1 0 2017 2017