Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 359
Gene Symbol: AQP2
AQP2
CUI: C0041956
Disease: Ureteral obstruction
Ureteral obstruction 		0.040 AlteredExpression BEFREE Bilateral ureteral obstruction is rapidly accompanied by ER stress and activation of autophagic degradation of IMCD proteins including AQP2. 31736351

2020
Entrez Id: 359
Gene Symbol: AQP2
AQP2
CUI: C0041956
Disease: Ureteral obstruction
Ureteral obstruction 		0.040 Biomarker BEFREE Inhibition of IL-1β by Aliskiren Improved Renal AQP2 Expression and Urinary Concentration Defect in Ureteral Obstruction and Release. 31572210

2019
Entrez Id: 359
Gene Symbol: AQP2
AQP2
CUI: C0041956
Disease: Ureteral obstruction
Ureteral obstruction 		0.040 AlteredExpression BEFREE TAM attenuated the downregulation of AQP2 in TGF-β treated IMCD cells and IMCD suspensions prepared from UUO rats. 31447686

2019
Entrez Id: 359
Gene Symbol: AQP2
AQP2
CUI: C0041956
Disease: Ureteral obstruction
Ureteral obstruction 		0.040 AlteredExpression BEFREE However, whether EPO could promote the recovery of renal function and AQP2 expression after releasing of ureteral obstruction has not been reported yet. 29959186

2018