| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
interleukin 6 | 0.248 | 0.962 | 0.32 |
|
phenotype | 0.010 | None | 1.000 | 1 | 0 | 2017 | 2017 | ||||||||
|
C-reactive protein | 0.299 | 0.962 | 3.7E-03 |
|
phenotype | 0.020 | None | 1.000 | 2 | 0 | 2018 | 2018 | ||||||||
|
cyclin dependent kinase inhibitor 2A | 0.300 | 0.885 | 0.39 |
|
phenotype | 0.010 | None | 1.000 | 1 | 1 | 2013 | 2013 | ||||||||
|
toll like receptor 4 | 0.321 | 0.962 | 4.6E-09 |
|
phenotype | 0.010 | None | 1.000 | 1 | 0 | 2020 | 2020 | ||||||||
|
angiotensin I converting enzyme | 0.328 | 0.923 | 1.0E-37 |
|
phenotype | 0.010 | None | < 0.001 | 1 | 0 | 2009 | 2009 | ||||||||
|
methylenetetrahydrofolate reductase | 0.337 | 0.885 | 3.2E-10 |
|
phenotype | 0.020 | None | 0.500 | 2 | 1 | 2009 | 2018 | ||||||||
|
brain derived neurotrophic factor | 0.345 | 0.923 | 0.66 |
|
phenotype | 0.020 | None | 0.500 | 2 | 2 | 2013 | 2020 | ||||||||
|
leptin | 0.349 | 0.846 | 0.46 |
|
phenotype | 0.040 | None | 1.000 | 4 | 0 | 2017 | 2020 | ||||||||
|
proopiomelanocortin | 0.356 | 0.846 | 1.2E-04 |
|
phenotype | 0.010 | None | 1.000 | 1 | 0 | 2020 | 2020 | ||||||||
|
peroxisome proliferator activated receptor gamma | 0.358 | 0.885 | 2.9E-02 |
|
phenotype | 0.010 | None | 1.000 | 1 | 0 | 2007 | 2007 | ||||||||
|
adiponectin, C1Q and collagen domain containing | 0.376 | 0.885 | 4.6E-09 |
|
phenotype | 0.040 | None | 1.000 | 4 | 0 | 2017 | 2019 | ||||||||
|
insulin like growth factor 2 | 0.390 | 0.885 | 4.4E-02 |
|
phenotype | 0.010 | None | 1.000 | 1 | 0 | 2012 | 2012 | ||||||||
|
parathyroid hormone | 0.397 | 0.846 | 1.2E-02 |
|
phenotype | 0.020 | None | 1.000 | 2 | 0 | 2019 | 2020 | ||||||||
|
glutamic--pyruvic transaminase | 0.403 | 0.923 | 3.6E-19 |
|
phenotype | 0.040 | None | 0.750 | 4 | 0 | 2018 | 2020 | ||||||||
|
paraoxonase 1 | 0.409 | 0.885 | 9.8E-11 |
|
phenotype | 0.020 | None | 1.000 | 2 | 2 | 2014 | 2019 | ||||||||
|
haptoglobin | 0.412 | 0.885 | 1.7E-05 |
|
phenotype | 0.010 | None | 1.000 | 1 | 0 | 2018 | 2018 | ||||||||
|
adrenoceptor beta 2 | 0.442 | 0.923 | 0.53 |
|
phenotype | 0.010 | None | 1.000 | 1 | 0 | 2008 | 2008 | ||||||||
|
PPARG coactivator 1 alpha | 0.453 | 0.885 | 1.00 |
|
phenotype | 0.010 | None | 1.000 | 1 | 0 | 2017 | 2017 | ||||||||
|
sclerostin | 0.474 | 0.808 | 0.87 |
|
phenotype | 0.010 | None | 1.000 | 1 | 0 | 2019 | 2019 | ||||||||
|
pancreatic and duodenal homeobox 1 | 0.530 | 0.654 | 1.8E-02 |
|
phenotype | 0.010 | None | 1.000 | 1 | 0 | 2013 | 2013 | ||||||||
|
ATP synthase F0 subunit 6 | 0.541 | 0.731 |
|
phenotype | 0.010 | None | < 0.001 | 1 | 0 | 2016 | 2016 | |||||||||
|
uncoupling protein 1 | 0.545 | 0.769 | 1.7E-11 |
|
phenotype | 0.010 | None | 1.000 | 1 | 0 | 2018 | 2018 | ||||||||
|
proprotein convertase subtilisin/kexin type 1 | 0.548 | 0.615 | 2.7E-09 |
|
phenotype | 0.010 | None | 1.000 | 1 | 1 | 2014 | 2014 | ||||||||
|
regulator of G protein signaling 2 | 0.561 | 0.769 | 5.7E-06 |
|
phenotype | 0.010 | None | 1.000 | 1 | 0 | 2008 | 2008 | ||||||||
|
phosducin | 0.581 | 0.731 | 1.0E-04 |
|
phenotype | 0.010 | None | 1.000 | 1 | 1 | 2013 | 2013 |