Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
tumor protein p53 0.236 0.962 0.53
Malignant neoplasm of colon and/or rectum
disease 0.100 None 0.949 331 8 1990 2020
Entrez Id: 324
Gene Symbol: APC
APC
APC regulator of WNT signaling pathway 0.373 0.962 1.00
Malignant neoplasm of colon and/or rectum
disease 0.100 None 0.982 165 11 1990 2019
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
prostaglandin-endoperoxide synthase 2 0.314 0.962 1.00
Malignant neoplasm of colon and/or rectum
disease 0.100 None 1.000 148 2 1998 2020
Entrez Id: 4513
Gene Symbol: COX2
COX2
cytochrome c oxidase subunit II 0.352 0.962
Malignant neoplasm of colon and/or rectum
disease 0.100 None 0.987 78 0 1998 2020
Entrez Id: 107075310
Gene Symbol: MTCO2P12
MTCO2P12
MT-CO2 pseudogene 12 0.368 0.962
Malignant neoplasm of colon and/or rectum
disease 0.100 None 1.000 72 0 1998 2020
Entrez Id: 960
Gene Symbol: CD44
CD44
CD44 molecule (Indian blood group) 0.363 0.962 2.4E-07
Malignant neoplasm of colon and/or rectum
disease 0.100 None 0.962 53 1 1995 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF
tumor necrosis factor 0.231 0.962 0.80
Malignant neoplasm of colon and/or rectum
disease 0.100 None 0.979 48 0 1989 2019
Entrez Id: 207
Gene Symbol: AKT1
AKT1
AKT serine/threonine kinase 1 0.311 0.962 0.98
Malignant neoplasm of colon and/or rectum
disease 0.100 None 1.000 45 0 2005 2020
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
transforming growth factor beta 1 0.287 0.962 3.7E-02
Malignant neoplasm of colon and/or rectum
disease 0.100 None 0.976 41 1 1995 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6
interleukin 6 0.248 0.962 0.32
Malignant neoplasm of colon and/or rectum
disease 0.100 None 0.969 32 1 2003 2020
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
toll like receptor 4 0.321 0.962 4.6E-09
Malignant neoplasm of colon and/or rectum
disease 0.100 None 1.000 25 4 2006 2019
Entrez Id: 1401
Gene Symbol: CRP
CRP
C-reactive protein 0.299 0.962 3.7E-03
Malignant neoplasm of colon and/or rectum
disease 0.100 None 0.955 22 2 2009 2019
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
C-X-C motif chemokine ligand 8 0.310 0.962 2.7E-04
Malignant neoplasm of colon and/or rectum
disease 0.100 None 1.000 20 0 2009 2019
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
interferon gamma 0.288 0.962 0.47
Malignant neoplasm of colon and/or rectum
disease 0.100 None 1.000 12 0 2010 2019
Entrez Id: 213
Gene Symbol: ALB
ALB
albumin 0.317 0.962 0.64
Malignant neoplasm of colon and/or rectum
disease 0.100 None 0.900 10 0 2014 2019
Entrez Id: 3565
Gene Symbol: IL4
IL4
interleukin 4 0.332 0.962 4.7E-03
Malignant neoplasm of colon and/or rectum
disease 0.100 None 1.000 10 0 1999 2019
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
interleukin 1 alpha 0.333 0.962 1.6E-04
Malignant neoplasm of colon and/or rectum
disease 0.090 None 1.000 9 2 2010 2019
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
interleukin 1 beta 0.276 0.962 0.13
Malignant neoplasm of colon and/or rectum
disease 0.080 None 1.000 8 3 1997 2019
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3
NLR family pyrin domain containing 3 0.361 0.962 8.1E-04
Malignant neoplasm of colon and/or rectum
disease 0.070 None 1.000 7 0 2012 2020
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
estrogen receptor 1 0.324 0.962 1.00
Malignant neoplasm of colon and/or rectum
disease 0.070 None 1.000 7 0 2006 2019
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
intercellular adhesion molecule 1 0.364 0.962 3.5E-02
Malignant neoplasm of colon and/or rectum
disease 0.060 None 1.000 6 1 1998 2017
Entrez Id: 5879
Gene Symbol: RAC1
RAC1
Rac family small GTPase 1 0.429 0.962 0.76
Malignant neoplasm of colon and/or rectum
disease 0.060 None 1.000 6 0 2007 2019
Entrez Id: 2335
Gene Symbol: FN1
FN1
fibronectin 1 0.365 0.962 1.4E-03
Malignant neoplasm of colon and/or rectum
disease 0.050 None 1.000 5 0 2010 2019
Entrez Id: 348
Gene Symbol: APOE
APOE
apolipoprotein E 0.338 0.962 1.9E-03
Malignant neoplasm of colon and/or rectum
disease 0.050 None 1.000 5 0 2001 2009
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
C-C motif chemokine ligand 2 0.321 0.962 0.61
Malignant neoplasm of colon and/or rectum
disease 0.050 None 1.000 5 0 2007 2019