Source: CTD_human

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2
Gene Symbol: A2M
A2M
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.300 Biomarker CTD_human Notably, we demonstrate significant regulation of alpha-1-antitrypsin, alpha-2-macroglobulin, hemoglobin subunit alpha, vitamin D-binding protein, major urinary proteins, and transthyretin (up to eight-fold) in serum of lung tumor bearing mice. 17902193

2007

Entrez Id: 2
Gene Symbol: A2M
A2M
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.300 Biomarker CTD_human Notably, expression of alpha-2-macroglobulin, transthyretin, alpha-1-antitrypsin, and properdin was in common in different lung tumor models, but regulation of orosomucoid-8, apolipoprotein-A1, apolipoprotein-C3, apolipoprotein-E, glutathione peroxidase-3, plasma retinol-binding protein, and serum amyloid P component was unique when the serum proteomes of c-myc and c-raf tumor bearing mice were compared. 19180532

2009

Entrez Id: 1636
Gene Symbol: ACE
ACE
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.310 Biomarker CTD_human Varied pathways of stage IA lung adenocarcinomas discovered by integrated gene expression analysis. 21552421

2011

Entrez Id: 116285
Gene Symbol: ACSM1
ACSM1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.300 Biomarker CTD_human A comparison of transcriptomic and metabonomic technologies for identifying biomarkers predictive of two-year rodent cancer bioassays. 17114358

2007

Entrez Id: 60
Gene Symbol: ACTB
ACTB
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.310 Biomarker CTD_human Proteomic analysis of differentially expressed proteins in lung cancer in Wistar rats using NNK as an inducer. 23692979

2013

Entrez Id: 100
Gene Symbol: ADA
ADA
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.300 Biomarker CTD_human [Increase of the functional activity of natural killers under the effects of the pharmacological correction of the sympathoadrenal system state in patients with lung cancer]. 2305558

1990

Entrez Id: 10863
Gene Symbol: ADAM28
ADAM28
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.300 Biomarker CTD_human ADAM28: a potential oncogene involved in asbestos-related lung adenocarcinomas. 20544843

2010

Entrez Id: 207
Gene Symbol: AKT1
AKT1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.500 Therapeutic CTD_human Rapid Akt activation by nicotine and a tobacco carcinogen modulates the phenotype of normal human airway epithelial cells. 12511591

2003

Entrez Id: 207
Gene Symbol: AKT1
AKT1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.500 Biomarker CTD_human Suppression of lung cancer progression by biocompatible glycerol triacrylate-spermine-mediated delivery of shAkt1. 22619562

2012

Entrez Id: 207
Gene Symbol: AKT1
AKT1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.500 Therapeutic CTD_human Suppression of lung cancer progression by biocompatible glycerol triacrylate-spermine-mediated delivery of shAkt1. 22619562

2012

Entrez Id: 207
Gene Symbol: AKT1
AKT1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.500 Biomarker CTD_human Aerosol delivery of spermine-based poly(amino ester)/Akt1 shRNA complexes for lung cancer gene therapy. 21911043

2011

Entrez Id: 207
Gene Symbol: AKT1
AKT1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.500 Therapeutic CTD_human Aerosol delivery of spermine-based poly(amino ester)/Akt1 shRNA complexes for lung cancer gene therapy. 21911043

2011

Entrez Id: 207
Gene Symbol: AKT1
AKT1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.500 Biomarker CTD_human Rapid Akt activation by nicotine and a tobacco carcinogen modulates the phenotype of normal human airway epithelial cells. 12511591

2003

Entrez Id: 60529
Gene Symbol: ALX4
ALX4
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.300 Biomarker CTD_human Epigenetic silencing of Aristaless-like homeobox-4, a potential tumor suppressor gene associated with lung cancer. 24037716

2014

Entrez Id: 288
Gene Symbol: ANK3
ANK3
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.300 Biomarker CTD_human Bronchial airway gene expression signatures in mouse lung squamous cell carcinoma and their modulation by cancer chemopreventive agents. 27935865

2017

Entrez Id: 253650
Gene Symbol: ANKRD18A
ANKRD18A
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.300 Biomarker CTD_human ANKRD18A as a novel epigenetic regulation gene in lung cancer. 23131552

2012

Entrez Id: 302
Gene Symbol: ANXA2
ANXA2
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.310 Biomarker CTD_human Identification of a tumour associated antigen in lung cancer patients with asbestos exposure. 20682992

2010

Entrez Id: 324
Gene Symbol: APC
APC
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.320 Biomarker CTD_human DNA methylation markers and early recurrence in stage I lung cancer. 18337602

2008

Entrez Id: 335
Gene Symbol: APOA1
APOA1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.310 Biomarker CTD_human Notably, expression of alpha-2-macroglobulin, transthyretin, alpha-1-antitrypsin, and properdin was in common in different lung tumor models, but regulation of orosomucoid-8, apolipoprotein-A1, apolipoprotein-C3, apolipoprotein-E, glutathione peroxidase-3, plasma retinol-binding protein, and serum amyloid P component was unique when the serum proteomes of c-myc and c-raf tumor bearing mice were compared. 19180532

2009

Entrez Id: 345
Gene Symbol: APOC3
APOC3
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.300 Biomarker CTD_human Notably, expression of alpha-2-macroglobulin, transthyretin, alpha-1-antitrypsin, and properdin was in common in different lung tumor models, but regulation of orosomucoid-8, apolipoprotein-A1, apolipoprotein-C3, apolipoprotein-E, glutathione peroxidase-3, plasma retinol-binding protein, and serum amyloid P component was unique when the serum proteomes of c-myc and c-raf tumor bearing mice were compared. 19180532

2009

Entrez Id: 348
Gene Symbol: APOE
APOE
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.320 Biomarker CTD_human Notably, expression of alpha-2-macroglobulin, transthyretin, alpha-1-antitrypsin, and properdin was in common in different lung tumor models, but regulation of orosomucoid-8, apolipoprotein-A1, apolipoprotein-C3, apolipoprotein-E, glutathione peroxidase-3, plasma retinol-binding protein, and serum amyloid P component was unique when the serum proteomes of c-myc and c-raf tumor bearing mice were compared. 19180532

2009

Entrez Id: 348
Gene Symbol: APOE
APOE
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.320 Biomarker CTD_human Apolipoprotein E expression promotes lung adenocarcinoma proliferation and migration and as a potential survival marker in lung cancer. 20430468

2011

Entrez Id: 60673
Gene Symbol: ATG101
ATG101
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.300 Biomarker CTD_human Bronchial airway gene expression signatures in mouse lung squamous cell carcinoma and their modulation by cancer chemopreventive agents. 27935865

2017

Entrez Id: 475
Gene Symbol: ATOX1
ATOX1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.300 Biomarker CTD_human Knockdown of copper chaperone antioxidant-1 by RNA interference inhibits copper-stimulated proliferation of non-small cell lung carcinoma cells. 23624903

2013

Entrez Id: 60370
Gene Symbol: AVPI1
AVPI1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.300 Biomarker CTD_human Bronchial airway gene expression signatures in mouse lung squamous cell carcinoma and their modulation by cancer chemopreventive agents. 27935865

2017