×
Entrez Id: 7528
Gene Symbol: YY1
YY1
Diabetes Mellitus, Insulin-Dependent
0.200
Biomarker
RGD
Genetic variation in the multifunctional transcription factor Yy1 and type 1 diabetes mellitus in the BB rat.
15234341 2004
×
Entrez Id: 7528
Gene Symbol: YY1
YY1
Diabetes Mellitus, Insulin-Dependent
0.200
Therapeutic
RGD
Diabetes per se and metabolic state influence gene expression in tissue-dependent manner of BB/OK rats.
15619288 2005
×
Entrez Id: 7450
Gene Symbol: VWF
VWF
Diabetes Mellitus, Insulin-Dependent
0.220
Biomarker
RGD
Aortic endothelial cell von Willebrand factor content, and circulating plasminogen activator inhibitor-1 are increased, but expression of endothelial leukocyte adhesion molecules is unchanged in insulin-dependent diabetic BB rats.
10729383 2000
×
Entrez Id: 7409
Gene Symbol: VAV1
VAV1
Diabetes Mellitus, Insulin-Dependent
0.200
Biomarker
RGD
Differential expression of p95vav in primary lymphoid tissue of BB rats congenic for the lymphopenia gene.
10433093 1999
×
Entrez Id: 54658
Gene Symbol: UGT1A1
UGT1A1
Diabetes Mellitus, Insulin-Dependent
0.200
Biomarker
RGD
Molecular basis of bilirubin UDP-glucuronosyltransferase induction in spontaneously diabetic rats, acetone-treated rats and starved rats.
9841869 1998
×
Entrez Id: 7292
Gene Symbol: TNFSF4
TNFSF4
Diabetes Mellitus, Insulin-Dependent
0.210
Biomarker
MGD
Paradoxical dampening of anti-islet self-reactivity but promotion of diabetes by OX40 ligand.
14662903 2003
×
Entrez Id: 6775
Gene Symbol: STAT4
STAT4
Diabetes Mellitus, Insulin-Dependent
0.300
Biomarker
MGD
Late developmental plasticity in the T helper 17 lineage.
19119024 2009
×
Entrez Id: 6775
Gene Symbol: STAT4
STAT4
Diabetes Mellitus, Insulin-Dependent
0.300
Biomarker
MGD
Contrasting roles for STAT4 and STAT6 signal transduction pathways in murine renal ischemia-reperfusion injury.
12709397 2003
×
Entrez Id: 6775
Gene Symbol: STAT4
STAT4
Diabetes Mellitus, Insulin-Dependent
0.300
Biomarker
MGD
Autoimmune diabetes is blocked in Stat4-deficient mice.
15041039 2004
×
Entrez Id: 6571
Gene Symbol: SLC18A2
SLC18A2
Diabetes Mellitus, Insulin-Dependent
0.210
Biomarker
RGD
Longitudinal noninvasive PET-based beta cell mass estimates in a spontaneous diabetes rat model.
16710474 2006
×
Entrez Id: 29843
Gene Symbol: SENP1
SENP1
Diabetes Mellitus, Insulin-Dependent
0.200
Biomarker
MGD
×
Entrez Id: 6402
Gene Symbol: SELL
SELL
Diabetes Mellitus, Insulin-Dependent
0.220
Biomarker
MGD
Changes in the expression of many Ets family transcription factors and of potential target genes in normal mammary tissue and tumors.
14662758 2004
×
Entrez Id: 5799
Gene Symbol: PTPRN2
PTPRN2
Diabetes Mellitus, Insulin-Dependent
0.300
Biomarker
MGD
×
Entrez Id: 5798
Gene Symbol: PTPRN
PTPRN
Diabetes Mellitus, Insulin-Dependent
0.300
Biomarker
RGD
The 37/40-kilodalton autoantigen in insulin-dependent diabetes mellitus is the putative tyrosine phosphatase IA-2.
7568143 1995
×
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
Diabetes Mellitus, Insulin-Dependent
0.900
SusceptibilityMutation
RGD
These findings are consistent with a role for rat Ptpn22 allelic variation within Iddm26.2 in the regulation of T cell responses, and subsequently the risk for development of T1D .
25505293 2015
×
Entrez Id: 5644
Gene Symbol: PRSS1
PRSS1
Diabetes Mellitus, Insulin-Dependent
0.310
Biomarker
RGD
Rat trypsin: purification, radioimmunoassay and age-related serum levels in normal and spontaneously diabetic BB Wistar rats.
3833185 1985
×
Entrez Id: 5551
Gene Symbol: PRF1
PRF1
Diabetes Mellitus, Insulin-Dependent
0.210
Biomarker
MGD
Islet-specific expression of IL-10 promotes diabetes in nonobese diabetic mice independent of Fas, perforin, TNF receptor-1, and TNF receptor-2 molecules.
10946317 2000
×
Entrez Id: 3651
Gene Symbol: PDX1
PDX1
Diabetes Mellitus, Insulin-Dependent
0.260
Biomarker
MGD
×
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
Diabetes Mellitus, Insulin-Dependent
0.250
Biomarker
MGD
×
Entrez Id: 4760
Gene Symbol: NEUROD1
NEUROD1
Diabetes Mellitus, Insulin-Dependent
0.300
Biomarker
MGD
Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/neuroD-deficient mice.
9308961 1997
×
Entrez Id: 3958
Gene Symbol: LGALS3
LGALS3
Diabetes Mellitus, Insulin-Dependent
0.240
Biomarker
RGD
In summary, combined proteome-transcriptome-genome and functional analyses identify gal-3 as a candidate gene/protein in T1D susceptibility that may prove valuable in future intervention/prevention strategies.
16600178 2006
×
Entrez Id: 11213
Gene Symbol: IRAK3
IRAK3
Diabetes Mellitus, Insulin-Dependent
0.200
Biomarker
MGD
IRAK-M deficiency promotes the development of type 1 diabetes in NOD mice.
24696448 2014
×
Entrez Id: 3630
Gene Symbol: INS
INS
Diabetes Mellitus, Insulin-Dependent
0.700
Biomarker
CTD_mouse
A sensitized screen of N-ethyl-N-nitrosourea-mutagenized mice identifies dominant mutants predisposed to diabetic nephropathy.
17151334 2007
×
Entrez Id: 3630
Gene Symbol: INS
INS
Diabetes Mellitus, Insulin-Dependent
0.700
Biomarker
CTD_mouse
Inhibition of SREBP With Fatostatin Does Not Attenuate Early Diabetic Nephropathy in Male Mice.
29420703 2018
×
Entrez Id: 3630
Gene Symbol: INS
INS
Diabetes Mellitus, Insulin-Dependent
0.700
Biomarker
MGD
Integrin α1/Akita double-knockout mice on a Balb/c background develop advanced features of human diabetic nephropathy.
22297672 2012