Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2706
Gene Symbol: GJB2
GJB2
Sensorineural hearing loss, bilateral
0.340 Biomarker MGD

Entrez Id: 81624
Gene Symbol: DIAPH3
DIAPH3
Sensorineural hearing loss, bilateral
0.200 Biomarker MGD

Entrez Id: 25861
Gene Symbol: WHRN
WHRN
Sensorineural hearing loss, bilateral
0.200 Biomarker MGD Metabolic and endocrine differences between the mutation whirler and normal female mice. 6034501

1967

Entrez Id: 25861
Gene Symbol: WHRN
WHRN
Sensorineural hearing loss, bilateral
0.200 Biomarker MGD Metabolism rate, biochemical and endocrine alterations in male whirler mice. 5538400

1970

Entrez Id: 117531
Gene Symbol: TMC1
TMC1
Sensorineural hearing loss, bilateral
0.200 Biomarker MGD The nature of inherited deafness in deafness mice. 7432512

1980

Entrez Id: 117531
Gene Symbol: TMC1
TMC1
Sensorineural hearing loss, bilateral
0.200 Biomarker MGD Preservation of central auditory function in the deafness mouse. 7093705

1982

Entrez Id: 117531
Gene Symbol: TMC1
TMC1
Sensorineural hearing loss, bilateral
0.200 Biomarker MGD Early degeneration of sensory and ganglion cells in the inner ear of mice with uncomplicated genetic deafness (dn): preliminary observations. 6662828

1983

Entrez Id: 117531
Gene Symbol: TMC1
TMC1
Sensorineural hearing loss, bilateral
0.200 Biomarker MGD Electrically-evoked responses in animals with progressive spiral ganglion degeneration. 6541219

1984

Entrez Id: 117531
Gene Symbol: TMC1
TMC1
Sensorineural hearing loss, bilateral
0.200 Biomarker MGD Distortion product otoacoustic emissions in hearing-impaired mutant mice. 4067076

1985

Entrez Id: 117531
Gene Symbol: TMC1
TMC1
Sensorineural hearing loss, bilateral
0.200 Biomarker MGD Degeneration followed by partial regeneration of the organ of Corti in deafness (dn/dn) mice. 1728569

1992

Entrez Id: 4646
Gene Symbol: MYO6
MYO6
Sensorineural hearing loss, bilateral
0.300 Biomarker MGD The mouse Snell's waltzer deafness gene encodes an unconventional myosin required for structural integrity of inner ear hair cells. 7493015

1995

Entrez Id: 117531
Gene Symbol: TMC1
TMC1
Sensorineural hearing loss, bilateral
0.200 Biomarker MGD The deafness locus (dn) maps to mouse chromosome 19. 7719036

1995

Entrez Id: 25861
Gene Symbol: WHRN
WHRN
Sensorineural hearing loss, bilateral
0.200 Biomarker MGD WHIRLER MICE: A RECESSIVE BEHAVIOR MUTATION IN LINKAGE GROUP VIII. 14098314

1996

Entrez Id: 4646
Gene Symbol: MYO6
MYO6
Sensorineural hearing loss, bilateral
0.300 Biomarker MGD Role of myosin VI in the differentiation of cochlear hair cells. 10525338

1999

Entrez Id: 1302
Gene Symbol: COL11A2
COL11A2
Sensorineural hearing loss, bilateral
0.200 Biomarker MGD Mutations in COL11A2 cause non-syndromic hearing loss (DFNA13). 10581026

1999

Entrez Id: 1302
Gene Symbol: COL11A2
COL11A2
Sensorineural hearing loss, bilateral
0.200 Biomarker MGD Targeted disruption of Col11a2 produces a mild cartilage phenotype in transgenic mice: comparison with the human disorder otospondylomegaepiphyseal dysplasia (OSMED). 11668593

2001

Entrez Id: 25861
Gene Symbol: WHRN
WHRN
Sensorineural hearing loss, bilateral
0.200 Biomarker MGD Elongation of hair cell stereocilia is defective in the mouse mutant whirler. 12124769

2002

Entrez Id: 4646
Gene Symbol: MYO6
MYO6
Sensorineural hearing loss, bilateral
0.300 Biomarker MGD Myo15 function is distinct from Myo6, Myo7a and pirouette genes in development of cochlear stereocilia. 12966030

2003

Entrez Id: 10083
Gene Symbol: USH1C
USH1C
Sensorineural hearing loss, bilateral
0.200 Biomarker MGD Mouse models of USH1C and DFNB18: phenotypic and molecular analyses of two new spontaneous mutations of the Ush1c gene. 14519688

2003

Entrez Id: 23562
Gene Symbol: CLDN14
CLDN14
Sensorineural hearing loss, bilateral
0.200 Biomarker MGD Claudin 14 knockout mice, a model for autosomal recessive deafness DFNB29, are deaf due to cochlear hair cell degeneration. 12913076

2003

Entrez Id: 59341
Gene Symbol: TRPV4
TRPV4
Sensorineural hearing loss, bilateral
0.200 Biomarker MGD Impaired pressure sensation in mice lacking TRPV4. 12692122

2003

Entrez Id: 10804
Gene Symbol: GJB6
GJB6
Sensorineural hearing loss, bilateral
0.200 Biomarker MGD Connexin30 (Gjb6)-deficiency causes severe hearing impairment and lack of endocochlear potential. 12490528

2003

Entrez Id: 9381
Gene Symbol: OTOF
OTOF
Sensorineural hearing loss, bilateral
0.500 Biomarker MGD Random mutagenesis of proximal mouse chromosome 5 uncovers predominantly embryonic lethal mutations. 16024820

2005

Entrez Id: 4646
Gene Symbol: MYO6
MYO6
Sensorineural hearing loss, bilateral
0.300 Biomarker MGD Myosin VI is required for normal retinal function. 15978262

2005

Entrez Id: 59341
Gene Symbol: TRPV4
TRPV4
Sensorineural hearing loss, bilateral
0.200 Biomarker MGD Hearing impairment in TRPV4 knockout mice. 15925108

2005