|
| Entrez Id: |
2706 |
| Gene Symbol: |
GJB2 |
GJB2
|
Sensorineural hearing loss, bilateral
|
0.340 |
Biomarker |
MGD |
|
|
|
|
| Entrez Id: |
81624 |
| Gene Symbol: |
DIAPH3 |
DIAPH3
|
Sensorineural hearing loss, bilateral
|
0.200 |
Biomarker |
MGD |
|
|
|
|
| Entrez Id: |
220074 |
| Gene Symbol: |
LRTOMT |
LRTOMT
|
Sensorineural hearing loss, bilateral
|
0.200 |
Biomarker |
MGD |
A catechol-O-methyltransferase that is essential for auditory function in mice and humans.
|
18794526 |
2008 |
|
| Entrez Id: |
7007 |
| Gene Symbol: |
TECTA |
TECTA
|
Sensorineural hearing loss, bilateral
|
0.200 |
Biomarker |
MGD |
A deafness mutation isolates a second role for the tectorial membrane in hearing.
|
15995703 |
2005 |
|
| Entrez Id: |
64072 |
| Gene Symbol: |
CDH23 |
CDH23
|
Sensorineural hearing loss, bilateral
|
0.200 |
Biomarker |
MGD |
A forward genetics screen in mice identifies recessive deafness traits and reveals that pejvakin is essential for outer hair cell function.
|
17329413 |
2007 |
|
| Entrez Id: |
9381 |
| Gene Symbol: |
OTOF |
OTOF
|
Sensorineural hearing loss, bilateral
|
0.500 |
Biomarker |
MGD |
A missense mutation in the conserved C2B domain of otoferlin causes deafness in a new mouse model of DFNB9.
|
17967520 |
2007 |
|
| Entrez Id: |
146183 |
| Gene Symbol: |
OTOA |
OTOA
|
Sensorineural hearing loss, bilateral
|
0.200 |
Biomarker |
MGD |
A mouse model for human deafness DFNB22 reveals that hearing impairment is due to a loss of inner hair cell stimulation.
|
23129639 |
2012 |
|
| Entrez Id: |
53904 |
| Gene Symbol: |
MYO3A |
MYO3A
|
Sensorineural hearing loss, bilateral
|
0.200 |
Biomarker |
MGD |
A mouse model for human hearing loss DFNB30 due to loss of function of myosin IIIA.
|
21165622 |
2011 |
|
| Entrez Id: |
64072 |
| Gene Symbol: |
CDH23 |
CDH23
|
Sensorineural hearing loss, bilateral
|
0.200 |
Biomarker |
MGD |
A mouse model for nonsyndromic deafness (DFNB12) links hearing loss to defects in tip links of mechanosensory hair cells.
|
19270079 |
2009 |
|
| Entrez Id: |
64072 |
| Gene Symbol: |
CDH23 |
CDH23
|
Sensorineural hearing loss, bilateral
|
0.200 |
Biomarker |
MGD |
A new mouse mutant of the Cdh23 gene with early-onset hearing loss facilitates evaluation of otoprotection drugs.
|
20644563 |
2012 |
|
| Entrez Id: |
340990 |
| Gene Symbol: |
OTOG |
OTOG
|
Sensorineural hearing loss, bilateral
|
0.200 |
Biomarker |
MGD |
A new Otogelin ENU mouse model for autosomal-recessive nonsyndromic moderate hearing impairment.
|
26636018 |
2015 |
|
| Entrez Id: |
1690 |
| Gene Symbol: |
COCH |
COCH
|
Sensorineural hearing loss, bilateral
|
0.220 |
Biomarker |
MGD |
A targeted Coch missense mutation: a knock-in mouse model for DFNA9 late-onset hearing loss and vestibular dysfunction.
|
18697796 |
2008 |
|
| Entrez Id: |
64072 |
| Gene Symbol: |
CDH23 |
CDH23
|
Sensorineural hearing loss, bilateral
|
0.200 |
Biomarker |
MGD |
An ENU-induced mutation of Cdh23 causes congenital hearing loss, but no vestibular dysfunction, in mice.
|
21689626 |
2011 |
|
| Entrez Id: |
10804 |
| Gene Symbol: |
GJB6 |
GJB6
|
Sensorineural hearing loss, bilateral
|
0.200 |
Biomarker |
MGD |
ATP release through connexin hemichannels and gap junction transfer of second messengers propagate Ca2+ signals across the inner ear.
|
19047635 |
2008 |
|
| Entrez Id: |
9294 |
| Gene Symbol: |
S1PR2 |
S1PR2
|
Sensorineural hearing loss, bilateral
|
0.200 |
Biomarker |
MGD |
Autosomal-Recessive Hearing Impairment Due to Rare Missense Variants within S1PR2.
|
26805784 |
2016 |
|
| Entrez Id: |
51475 |
| Gene Symbol: |
CABP2 |
CABP2
|
Sensorineural hearing loss, bilateral
|
0.200 |
Biomarker |
MGD |
Ca2+-binding protein 2 inhibits Ca2+-channel inactivation in mouse inner hair cells.
|
28183797 |
2017 |
|
| Entrez Id: |
10518 |
| Gene Symbol: |
CIB2 |
CIB2
|
Sensorineural hearing loss, bilateral
|
0.200 |
Biomarker |
MGD |
CIB2, defective in isolated deafness, is key for auditory hair cell mechanotransduction and survival.
|
29084757 |
2017 |
|
| Entrez Id: |
23562 |
| Gene Symbol: |
CLDN14 |
CLDN14
|
Sensorineural hearing loss, bilateral
|
0.200 |
Biomarker |
MGD |
Claudin 14 knockout mice, a model for autosomal recessive deafness DFNB29, are deaf due to cochlear hair cell degeneration.
|
12913076 |
2003 |
|
| Entrez Id: |
25861 |
| Gene Symbol: |
WHRN |
WHRN
|
Sensorineural hearing loss, bilateral
|
0.200 |
Biomarker |
MGD |
Cochlear outer hair cells undergo an apical circumference remodeling constrained by the hair bundle shape.
|
20332152 |
2010 |
|
| Entrez Id: |
10804 |
| Gene Symbol: |
GJB6 |
GJB6
|
Sensorineural hearing loss, bilateral
|
0.200 |
Biomarker |
MGD |
Connexin30 (Gjb6)-deficiency causes severe hearing impairment and lack of endocochlear potential.
|
12490528 |
2003 |
|
| Entrez Id: |
10804 |
| Gene Symbol: |
GJB6 |
GJB6
|
Sensorineural hearing loss, bilateral
|
0.200 |
Biomarker |
MGD |
Connexin30 deficiency causes instrastrial fluid-blood barrier disruption within the cochlear stria vascularis.
|
17400755 |
2007 |
|
| Entrez Id: |
286676 |
| Gene Symbol: |
ILDR1 |
ILDR1
|
Sensorineural hearing loss, bilateral
|
0.200 |
Biomarker |
MGD |
Deficiency of angulin-2/ILDR1, a tricellular tight junction-associated membrane protein, causes deafness with cochlear hair cell degeneration in mice.
|
25822906 |
2015 |
|
| Entrez Id: |
117531 |
| Gene Symbol: |
TMC1 |
TMC1
|
Sensorineural hearing loss, bilateral
|
0.200 |
Biomarker |
MGD |
Degeneration followed by partial regeneration of the organ of Corti in deafness (dn/dn) mice.
|
1728569 |
1992 |
|
MARVELD2
|
Sensorineural hearing loss, bilateral
|
0.200 |
Biomarker |
MGD |
Deletion of Tricellulin Causes Progressive Hearing Loss Associated with Degeneration of Cochlear Hair Cells.
|
26677943 |
2015 |
|
| Entrez Id: |
117531 |
| Gene Symbol: |
TMC1 |
TMC1
|
Sensorineural hearing loss, bilateral
|
0.200 |
Biomarker |
MGD |
Distortion product otoacoustic emissions in hearing-impaired mutant mice.
|
4067076 |
1985 |