Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5919
Gene Symbol: RARRES2
RARRES2
FATTY LIVER DISEASE, NONALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Biomarker RGD Identification of chemerin as a novel FXR target gene down-regulated in the progression of nonalcoholic steatohepatitis. 23507574

2013

Entrez Id: 7099
Gene Symbol: TLR4
TLR4
FATTY LIVER DISEASE, NONALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Therapeutic RGD [Effect of electro-acupuncture on hepatic Toll-like receptor 4 and nuclear factor κB expressions in rats with non-alcoholic fatty liver disease]. 25413054

2014

Entrez Id: 3156
Gene Symbol: HMGCR
HMGCR
FATTY LIVER DISEASE, NONALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 ModifyingMutation RGD An atherogenic diet decreases liver FXR gene expression and causes severe hepatic steatosis and hepatic cholesterol accumulation: effect of endurance training. 23117815

2013

Entrez Id: 10891
Gene Symbol: PPARGC1A
PPARGC1A
FATTY LIVER DISEASE, NONALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Biomarker RGD Activation of peroxisome proliferator-activated receptor gamma by rosiglitazone increases sirt6 expression and ameliorates hepatic steatosis in rats. 21373642

2011

Entrez Id: 7099
Gene Symbol: TLR4
TLR4
FATTY LIVER DISEASE, NONALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Biomarker RGD Cross talk between toll-like receptor-4 signaling and angiotensin-II in liver fibrosis development in the rat model of non-alcoholic steatohepatitis. 23301938

2013

Entrez Id: 9971
Gene Symbol: NR1H4
NR1H4
FATTY LIVER DISEASE, NONALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Biomarker RGD Impaired VLDL assembly: a novel mechanism contributing to hepatic lipid accumulation following ovariectomy and high-fat/high-cholesterol diets? 25263431

2014

Entrez Id: 10062
Gene Symbol: NR1H3
NR1H3
FATTY LIVER DISEASE, NONALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Biomarker RGD Impaired VLDL assembly: a novel mechanism contributing to hepatic lipid accumulation following ovariectomy and high-fat/high-cholesterol diets? 25263431

2014

Entrez Id: 7351
Gene Symbol: UCP2
UCP2
FATTY LIVER DISEASE, NONALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Biomarker RGD Increased hepatic UCP2 expression in rats with nonalcoholic steatohepatitis is associated with upregulation of Sp1 binding to its motif within the proximal promoter region. 18543254

2008

Entrez Id: 23409
Gene Symbol: SIRT4
SIRT4
FATTY LIVER DISEASE, NONALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Biomarker RGD Calorie restriction on insulin resistance and expression of SIRT1 and SIRT4 in rats. 20651844

2010

Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
FATTY LIVER DISEASE, NONALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Biomarker RGD Molecular mechanism of altered ezetimibe disposition in nonalcoholic steatohepatitis. 22112382

2012

Entrez Id: 2936
Gene Symbol: GSR
GSR
FATTY LIVER DISEASE, NONALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Therapeutic RGD Comparative effect of pioglitazone, quercetin and hydroxy citric acid on the status of lipid peroxidation and antioxidants in experimental non-alcoholic steatohepatitis. 24622831

2014

Entrez Id: 7124
Gene Symbol: TNF
TNF
FATTY LIVER DISEASE, NONALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Biomarker RGD Innate immune reactivity of the liver in rats fed a choline-deficient L-amino-acid-defined diet. 19034968

2008

Entrez Id: 1571
Gene Symbol: CYP2E1
CYP2E1
FATTY LIVER DISEASE, NONALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Therapeutic RGD Pioglitazone, quercetin and hydroxy citric acid effect on cytochrome P450 2E1 (CYP2E1) enzyme levels in experimentally induced non alcoholic steatohepatitis (NASH). 25317811

2014

Entrez Id: 3643
Gene Symbol: INSR
INSR
FATTY LIVER DISEASE, NONALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 SusceptibilityMutation RGD Insulin resistance promotes Lysyl Oxidase Like 2 induction and fibrosis accumulation in non-alcoholic fatty liver disease. 28468951

2017

Entrez Id: 1728
Gene Symbol: NQO1
NQO1
FATTY LIVER DISEASE, NONALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Therapeutic RGD Yinchen Linggui Zhugan Decoction Ameliorates Nonalcoholic Fatty Liver Disease in Rats by Regulating the Nrf2/ARE Signaling Pathway. 28932253

2017

Entrez Id: 3156
Gene Symbol: HMGCR
HMGCR
FATTY LIVER DISEASE, NONALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Biomarker RGD Impaired VLDL assembly: a novel mechanism contributing to hepatic lipid accumulation following ovariectomy and high-fat/high-cholesterol diets? 25263431

2014

Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
FATTY LIVER DISEASE, NONALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Therapeutic RGD Nrf2 activators attenuate the progression of nonalcoholic steatohepatitis-related fibrosis in a dietary rat model. 23592516

2013

Entrez Id: 9971
Gene Symbol: NR1H4
NR1H4
FATTY LIVER DISEASE, NONALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Therapeutic RGD Curative effect of arjunolic acid from Terminalia arjuna in non-alcoholic fatty liver disease models. 30257410

2018

Entrez Id: 6352
Gene Symbol: CCL5
CCL5
FATTY LIVER DISEASE, NONALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Therapeutic RGD Steatosis induced CCL5 contributes to early-stage liver fibrosis in nonalcoholic fatty liver disease progress. 27639593

2017

Entrez Id: 27141
Gene Symbol: CIDEB
CIDEB
FATTY LIVER DISEASE, NONALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Biomarker RGD Impaired VLDL assembly: a novel mechanism contributing to hepatic lipid accumulation following ovariectomy and high-fat/high-cholesterol diets? 25263431

2014

Entrez Id: 4023
Gene Symbol: LPL
LPL
FATTY LIVER DISEASE, NONALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Therapeutic RGD Thiazolidinedione induces a therapeutic effect on hepatosteatosis by regulating stearoyl-CoA desaturase-1, lipase activity, leptin and resistin. 30214514

2018

Entrez Id: 64240
Gene Symbol: ABCG5
ABCG5
FATTY LIVER DISEASE, NONALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Biomarker RGD Impaired VLDL assembly: a novel mechanism contributing to hepatic lipid accumulation following ovariectomy and high-fat/high-cholesterol diets? 25263431

2014

Entrez Id: 3240
Gene Symbol: HP
HP
FATTY LIVER DISEASE, NONALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Biomarker RGD Discovery of serum biomarkers of alcoholic fatty liver in a rodent model: C-reactive protein. 21806828

2011

Entrez Id: 5445
Gene Symbol: PON2
PON2
FATTY LIVER DISEASE, NONALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Therapeutic RGD Paraoxonase activity and expression is modulated by therapeutics in experimental rat nonalcoholic Fatty liver disease. 22536512

2012

Entrez Id: 60
Gene Symbol: ACTB
ACTB
FATTY LIVER DISEASE, NONALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Biomarker RGD Protein carbonylation associated to high-fat, high-sucrose diet and its metabolic effects. 25282656

2014