×
Entrez Id: 330
Gene Symbol: BIRC3
BIRC3
Mesothelioma
0.010
Biomarker
LHGDN
Our observations strongly suggest that IAP-1 is at least partly responsible for promoting carcinogenesis and mediating resistance to cisplatin in many MPM tumors and that further study of this apoptotic pathway is warranted.
12082024 2002
×
Entrez Id: 4771
Gene Symbol: NF2
NF2
Mesothelioma
0.400
Biomarker
LHGDN
Mutational analysis of the nf2 tumour suppressor gene in three subtypes of primary human malignant mesotheliomas.
12684666 2003
×
Entrez Id: 2272
Gene Symbol: FHIT
FHIT
Mesothelioma
0.310
AlteredExpression
LHGDN
Reduced Fhit protein expression in human malignant mesothelioma.
14569398 2004
×
Entrez Id: 673
Gene Symbol: BRAF
BRAF
Mesothelioma
0.010
GeneticVariation
LHGDN
Mutation analysis of the BRAF codon 599 in malignant pleural mesothelioma by enriched PCR-RFLP.
14719068 2004
CHRFAM7A
Mesothelioma
0.010
AlteredExpression
LHGDN
Alpha7-nicotinic acetylcholine receptors affect growth regulation of human mesothelioma cells: role of mitogen-activated protein kinase pathway.
14729617 2004
×
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
Mesothelioma
0.020
AlteredExpression
LHGDN
Abrogation of p21 expression by flavopiridol enhances depsipeptide-mediated apoptosis in malignant pleural mesothelioma cells.
15014036 2004
TNFRSF10B
Mesothelioma
0.010
AlteredExpression
LHGDN
FLIP overexpression inhibits death receptor-induced apoptosis in malignant mesothelial cells.
15334061 2004
×
Entrez Id: 8837
Gene Symbol: CFLAR
CFLAR
Mesothelioma
0.010
AlteredExpression
LHGDN
FLIP overexpression inhibits death receptor-induced apoptosis in malignant mesothelial cells.
15334061 2004
TNFRSF10A
Mesothelioma
0.010
AlteredExpression
LHGDN
FLIP overexpression inhibits death receptor-induced apoptosis in malignant mesothelial cells.
15334061 2004
×
Entrez Id: 6591
Gene Symbol: SNAI2
SNAI2
Mesothelioma
0.010
Biomarker
LHGDN
Induction of stem cell factor/c-Kit/slug signal transduction in multidrug-resistant malignant mesothelioma cells.
15337769 2004
×
Entrez Id: 3815
Gene Symbol: KIT
KIT
Mesothelioma
0.010
Biomarker
LHGDN
Induction of stem cell factor/c-Kit/slug signal transduction in multidrug-resistant malignant mesothelioma cells.
15337769 2004
×
Entrez Id: 4254
Gene Symbol: KITLG
KITLG
Mesothelioma
0.010
Biomarker
LHGDN
Induction of stem cell factor/c-Kit/slug signal transduction in multidrug-resistant malignant mesothelioma cells.
15337769 2004
×
Entrez Id: 1028
Gene Symbol: CDKN1C
CDKN1C
Mesothelioma
0.010
PosttranslationalModification
LHGDN
The promoter region of p57KIP2 was determined by methylation-specific PCR (MSP) in samples of lung and breast cancer, and of MM .
15492797 2004
×
Entrez Id: 55600
Gene Symbol: ITLN1
ITLN1
Mesothelioma
0.320
AlteredExpression
LHGDN
Identification of intelectin overexpression in malignant pleural mesothelioma by serial analysis of gene expression (SAGE).
15777968 2005
×
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
Mesothelioma
0.030
AlteredExpression
LHGDN
Quantitative evaluation of the apoptosis regulating genes Survivin, Bcl-2 and Bax in inflammatory and malignant pleural lesions.
15829320 2005
×
Entrez Id: 7472
Gene Symbol: WNT2
WNT2
Mesothelioma
0.010
Biomarker
LHGDN
Wnt2 as a new therapeutic target in malignant pleural mesothelioma .15900580 2005
×
Entrez Id: 836
Gene Symbol: CASP3
CASP3
Mesothelioma
0.050
Biomarker
LHGDN
In the histological samples, caspase 3 and 8 immunoreactivity was seen in 27/37 (73%) and 16/37 (43%) of the mesotheliomas .
15996160 2005
×
Entrez Id: 9166
Gene Symbol: EBAG9
EBAG9
Mesothelioma
0.010
AlteredExpression
LHGDN
Clinical significance of the expression of tumor-associated antigen, RCAS1, and its soluble protein in pleural fluid in malignant mesothelioma.
16012715 2005
×
Entrez Id: 10232
Gene Symbol: MSLN
MSLN
Mesothelioma
0.600
Biomarker
LHGDN
Serum mesothelin levels were increased in 80% and 75% of the cases of mesothelioma and ovarian cancer, respectively, in which the tumors expressed mesothelin by immunohistochemistry.
16428485 2006
×
Entrez Id: 11197
Gene Symbol: WIF1
WIF1
Mesothelioma
0.020
AlteredExpression
LHGDN
Taken together, our studies suggest that WIF-1 silencing due to its promoter hypermethylation is an important mechanism underlying the constitutively activated Wnt signaling in mesothelioma .
16516163 2006
×
Entrez Id: 10232
Gene Symbol: MSLN
MSLN
Mesothelioma
0.600
Biomarker
LHGDN
Megakaryocyte potentiation factor cleaved from mesothelin precursor is a useful tumor marker in the serum of patients with mesothelioma .
16857795 2006
×
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
Mesothelioma
0.600
Biomarker
LHGDN
p53-induced apoptosis occurs in the absence of p14(ARF) in malignant pleural mesothelioma.
16867217 2006
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
Mesothelioma
0.300
Biomarker
LHGDN
p53-induced apoptosis occurs in the absence of p14(ARF) in malignant pleural mesothelioma.
16867217 2006
×
Entrez Id: 6513
Gene Symbol: SLC2A1
SLC2A1
Mesothelioma
0.020
Biomarker
LHGDN
Immunohistochemical detection of GLUT-1 can discriminate between reactive mesothelium and malignant mesothelioma.
17192790 2007
×
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
Mesothelioma
0.320
GeneticVariation
LHGDN
Polymorphisms of glutathione-S-transferase M1 and manganese superoxide dismutase are associated with the risk of malignant pleural mesothelioma.
17290392 2007